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Biology and Biochemistry

D-Index
50
Citations
9936
World Ranking
17566
National Ranking
7208

Overview

Lesley G. Ellies is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on various subfields including Molecular Biology, Physiology, Cancer Research, Oncology, and Endocrine and Autonomic Systems.

The scientist's research topics cover areas such as:

  • Diet and metabolism studies
  • Dietary Effects on Health
  • Circadian rhythm and melatonin
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Cancer, Hypoxia, and Metabolism
  • Cancer Immunotherapy and Biomarkers

Notable recent publications by Lesley G. Ellies include:

  • "Time-restricted feeding normalizes hyperinsulinemia to inhibit breast cancer in obese postmenopausal mouse models" (2021), Nature Communications
  • "Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma" (2022), Advanced Science
  • "Elevated BCAA Suppresses the Development and Metastasis of Breast Cancer" (2022), Frontiers in Oncology
  • "Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy" (2022), Science Advances
  • "A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer" (2022), Oncogenesis

Frequent collaborators of Ellies include:

  • Manasi Das
  • Consuelo Sauceda
  • Alexis Oberg
  • Nicholas J. G. Webster
  • Lily Jih

Ellies has publications across multiple research venues with repeated contributions to:

  • Nature Communications
  • Advanced Science
  • Frontiers in Oncology
  • Science Advances
  • Oncogenesis

Best Publications

  • The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny.

    Raheel Shafi;Sai Prasad N Iyer;Lesley G. Ellies;Niall O'Donnell

  • Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

    Emilia S. Olson;Tao Jiang;Todd A. Aguilera;Quyen T. Nguyen

  • Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

    Quyen T. Nguyen;Emilia S. Olson;Todd Anthony Aguilera;Tao Jiang

  • Receptor Tyrosine Kinases and TLR/IL1Rs Unexpectedly Activate Myeloid Cell PI3Kγ, A Single Convergent Point Promoting Tumor Inflammation and Progression

    Michael C. Schmid;Christie J. Avraamides;Holly C. Dippold;Irene Franco

  • Core 2 Oligosaccharide Biosynthesis Distinguishes between Selectin Ligands Essential for Leukocyte Homing and Inflammation

    Lesley G Ellies;Shigeru Tsuboi;Bronislawa Petryniak;John B Lowe

  • Novel Sulfated Lymphocyte Homing Receptors and Their Control by a Core1 Extension β1,3-N-Acetylglucosaminyltransferase

    Jiunn-Chern Yeh;Nobuyoshi Hiraoka;Bronislawa Petryniak;Jun Nakayama

  • In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

    Emilia S. Olson;Todd A. Aguilera;Tao Jiang;Lesley G. Ellies

  • Transgenic Polyoma Middle-T Mice Model Premalignant Mammary Disease

    Jeannie E. Maglione;Drew Moghanaki;Lawrence J. T. Young;Cathyryne K. Manner

  • Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands

    Lesley G. Ellies;David Ditto;Gallia G. Levy;Mark Wahrenbrock

  • Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.

    Ryan Kolb;Liem Phan;Liem Phan;Nicholas Borcherding;Yinghong Liu

  • Epidermal sensing of oxygen is essential for systemic hypoxic response.

    Adam T. Boutin;Alexander Weidemann;Zhenxing Fu;Lernik Mesropian

  • Real-time In Vivo Molecular Detection of Primary Tumors and Metastases with Ratiometric Activatable Cell-Penetrating Peptides

    Elamprakash N. Savariar;Csilla N. Felsen;Nadia Nashi;Tao Jiang

  • Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

    Cristina Branco-Price;Na Zhang;Moritz Schnelle;Colin Evans

  • Effects of FVB/NJ and C57Bl/6J strain backgrounds on mammary tumor phenotype in inducible nitric oxide synthase deficient mice

    Sarah A. Davie;Jeannie E. Maglione;Cathyryne K. Manner;Dmitri Young

  • Crystallographic changes in calcium phosphates during plasma-spraying.

    L.G. Ellies;D.G.A. Nelson;J.D.B. Featherstone

  • Reprogramming the immunological microenvironment through radiation and targeting Axl

    Todd A. Aguilera;Marjan Rafat;Laura Castellini;Hussein Shehade

  • Sialyltransferase specificity in selectin ligand formation.

    Lesley G. Ellies;Markus Sperandio;Markus Sperandio;Markus Sperandio;Gregory H. Underhill;Gregory H. Underhill;Gregory H. Underhill;James Yousif;James Yousif;James Yousif

  • Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice

    Henri H. Versteeg;Florence Schaffner;Marjolein Kerver;Lesley G. Ellies

  • Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase–deficient mice

    Markus Sperandio;Aravinda Thatte;Dan Foy;Lesley G. Ellies

  • Integrin α4β1 Signaling Is Required for Lymphangiogenesis and Tumor Metastasis

    Barbara Garmy-Susini;Christie J. Avraamides;Michael C. Schmid;Philippe Foubert

Frequent Co-Authors

Roger Y. Tsien
Roger Y. Tsien University of California, San Diego
Nicholas J. G. Webster
Nicholas J. G. Webster University of California, San Diego
Robert D. Cardiff
Robert D. Cardiff University of California, Davis
Jamey D. Marth
Jamey D. Marth University of California, Santa Barbara
Klaus Ley
Klaus Ley Augusta University
Geoffrey S. Kansas
Geoffrey S. Kansas Northwestern University
Markus Sperandio
Markus Sperandio Ludwig-Maximilians-Universität München
Albert C. Koong
Albert C. Koong The University of Texas MD Anderson Cancer Center
David A. Cheresh
David A. Cheresh University of California, San Diego
Amato J. Giaccia
Amato J. Giaccia Stanford University

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