Roger Y. Tsien

Research.com Recognitions

• 2025 - Research.com Best Scientists Award
• 2023 - Research.com Biology and Biochemistry in United States Leader Award
• 2012 - Fellow, National Academy of Inventors
• 2009 - Distinguished Scientist Award, American Heart Association
• 2008 - Nobel Prize for the discovery and development of the green fluorescent protein, GFP
• 2008 - E.B. Wilson Medal, American Society for Cell Biology
• 2005 - J. Allyn Taylor International Prize in Medicine, Robarts Research Institute
• 2004 - Keio Medical Science Prize, Keio University, Tokyo, Japan
• 2004 - Perl-UNC Prize, University of North Carolina at Chapel Hill Development of Tools for Monitoring Signaling in Living Nerve Cells.
• 1998 - Member of the National Academy of Sciences
• 1995 - Member of the National Academy of Medicine (NAM)
• 1995 - Canada Gairdner International Award
• 1991 - W. Alden Spencer Award, College of Physicians and Surgeons

Overview

Best Publications

• A new generation of Ca2+ indicators with greatly improved fluorescence properties.

  G. Grynkiewicz;Martin Poenie;R. Y. Tsien

  25731
  Citations

• THE GREEN FLUORESCENT PROTEIN

  Roger Y. Tsien

  9732
  Citations

• Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein.

  Nathan C Shaner;Robert E Campbell;Robert E Campbell;Paul A Steinbach;Ben N G Giepmans

  5514
  Citations

• Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

  Atsushi Miyawaki;Juan Llopis;Roger Heim;J. Michael McCaffery

  4157
  Citations

• A guide to choosing fluorescent proteins.

  Nathan C Shaner;Paul A Steinbach;Roger Y Tsien

  3626
  Citations

• The fluorescent toolbox for assessing protein location and function

  Ben N. G. Giepmans;Stephen R. Adams;Mark H. Ellisman;Roger Y. Tsien

  3346
  Citations

• New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures.

  Roger Y. Tsien

  3301
  Citations

• Crystal structure of the Aequorea victoria green fluorescent protein.

  M Ormö;A B Cubitt;K Kallio;L A Gross

  3272
  Citations

• A monomeric red fluorescent protein

  Robert E. Campbell;Oded Tour;Amy E. Palmer;Paul A. Steinbach

  3037
  Citations

• Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

  R Y Tsien;T Pozzan;T J Rink

  2766
  Citations

• Wavelength mutations and posttranslational autoxidation of green fluorescent protein

  Roger Heim;Douglas C. Prasher;Roger Y. Tsien

  2702
  Citations

• Improved green fluorescence

  Roger Heim;Andrew B. Cubitt;Roger Y. Tsien

  2692
  Citations

• Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells.

  David A. Zacharias;Jonathan D. Violin;Alexandra C. Newton;Roger Y. Tsien

  2671
  Citations

• Creating new fluorescent probes for cell biology.

  Jin Zhang;Robert E. Campbell;Alice Y. Ting;Alice Y. Ting;Roger Y. Tsien

  2488
  Citations

• Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

  Roger Heim;Roger Y Tsien

  2327
  Citations

• Understanding, improving and using green fluorescent proteins.

  Andrew B. Cubitt;Roger Heim;Stephen R. Adams;Aileen E. Boyd

  2106
  Citations

• Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores.

  A Minta;J P Y Kao;R Y Tsien

  2048
  Citations

• Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells

  B. Albert Griffin;Stephen R. Adams;Roger Y. Tsien

  2040
  Citations

• On/off blinking and switching behaviour of single molecules of green fluorescent protein

  Robert M. Dickson;Andrew B. Cubitt;Roger Y. Tsien;W. E. Moerner

  1785
  Citations

• Identification of a signal for rapid export of proteins from the nucleus

  Wei Wen;Judy L. Meinkoth;Roger Y. Tsien;Roger Y. Tsien;Susan S. Taylor

  1766
  Citations