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D-Index & Metrics

Molecular Biology

D-Index
73
Citations
40550
World Ranking
1255
National Ranking
644

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors
  • 2004 - Member of the National Academy of Sciences

Overview

Erin K. O'Shea is affiliated with the Howard Hughes Medical Institute in the United States. Their research is situated primarily in the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology, with a focus on several interconnected subfields including Cellular and Molecular Neuroscience, Molecular Biology, Neurology, Physiology, and Materials Chemistry.

Their recent publications cover topics central to neuronal communication, synaptic plasticity, and cellular mechanisms underlying neurodegeneration and neuroinflammation. Selected recent papers include:

  • The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking, 2024, eLife
  • Plasticity-induced actin polymerization in the dendritic shaft regulates intracellular AMPA receptor trafficking, 2022, bioRxiv (Cold Spring Harbor Laboratory)
  • Correction: Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway, 2022, eLife
  • Activity-dependent synapse elimination requires caspase-3 activation, 2024, bioRxiv (Cold Spring Harbor Laboratory)

The main topics of Erin K. O'Shea's research include:

  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Photoreceptor and optogenetics research
  • Lipid Membrane Structure and Behavior
  • Extracellular vesicles in disease
  • RNA regulation and disease
  • Photochromic and Fluorescence Chemistry

Frequent co-authors collaborating with Erin K. O'Shea are:

  • Michael C. DeSantis
  • Victor C. Wong
  • Deepika Walpita
  • Zhe Liu
  • Zhou Yu

The scientist's work has been published predominantly in eLife and bioRxiv (Cold Spring Harbor Laboratory), with a smaller number of publications in BIO-PROTOCOL.

Erin K. O'Shea has received recognition in their field, including being named a Fellow of the National Academy of Inventors in 2016 and elected as a Member of the National Academy of Sciences in 2004.

Best Publications

  • Global analysis of protein localization in budding yeast

    Won-Ki Huh;James V. Falvo;Luke C. Gerke;Adam S. Carroll

  • Global analysis of protein expression in yeast

    Sina Ghaemmaghami;Won-Ki Huh;Kiowa Bower;Russell W. Howson

  • Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

    Nevan J. Krogan;Gerard Cagney;Gerard Cagney;Haiyuan Yu;Gouqing Zhong

  • Noise in Gene Expression: Origins, Consequences, and Control

    Jonathan M. Raser;Erin K. O'Shea

  • Control of Stochasticity in Eukaryotic Gene Expression

    Jonathan M. Raser;Erin K. O'Shea

  • X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.

    Erin K. O'Shea;Juli D. Klemm;Peter S. Kim;Tom Alber

  • Evidence that the leucine zipper is a coiled coil

    Erin K. O'Shea;Rheba Rutkowski;Peter S. Kim

  • Noise in protein expression scales with natural protein abundance.

    Arren Bar-Even;Johan Paulsson;Johan Paulsson;Narendra Maheshri;Miri Carmi

  • Quantification of protein half-lives in the budding yeast proteome

    Archana Belle;Amos Tanay;Ledion Bitincka;Ron Shamir

  • Peptide 'Velcro': design of a heterodimeric coiled coil.

    Erin K. O'Shea;Kevin J. Lumb;Peter S. Kim

  • Mechanism of specificity in the Fos-Jun oncoprotein heterodimer

    Erin K. O'Shea;Rheba Rutkowski;Peter S. Kim

  • Preferential heterodimer formation by isolated leucine zippers from fos and jun.

    Erin K. O'Shea;Rheba Rutkowski;Walter F. Stafford;Walter F. Stafford;Peter S. Kim

  • Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions.

    James C. Hu;Erin K. O'Shea;Peter S. Kim;Robert T. Sauer

  • Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85

    Arie Kaffman;Ira Herskowitz;Robert Tjian;Robert Tjian;Erin K. O'Shea;Erin K. O'Shea

  • Living with noisy genes: how cells function reliably with inherent variability in gene expression.

    Narendra Maheshri;Erin K. O'Shea

  • Ordered Phosphorylation Governs Oscillation of a Three-Protein Circadian Clock

    Michael J. Rust;Joseph S. Markson;William S. Lane;Daniel S. Fisher

  • Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression

    Rosa M. Marion;Aviv Regev;Eran Segal;Yoseph Barash

  • Regulation of Chromatin Remodeling by Inositol Polyphosphates

    David J. Steger;Elizabeth S. Haswell;Aimee L. Miller;Susan R. Wente

  • The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

    Arie Kaffman;Nicole Miller Rank;Elizabeth M. O'Neill;Linda S. Huang

  • Signaling phosphate starvation

    Marc E. Lenburg;Erin K. O'Shea

Frequent Co-Authors

David J. Steger
David J. Steger University of Pennsylvania
Edoardo M. Airoldi
Edoardo M. Airoldi Temple University
Ira Herskowitz
Ira Herskowitz University of California, San Francisco
Noah Dephoure
Noah Dephoure Cornell University
Aviv Regev
Aviv Regev Genentech
Gerard Cagney
Gerard Cagney University College Dublin
Richard Losick
Richard Losick Harvard University
Joan A. Steitz
Joan A. Steitz Yale University

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