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Genetics

D-Index
54
Citations
24800
World Ranking
3608
National Ranking
16

Overview

Gerard Cagney is affiliated with University College Dublin in Ireland and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans multiple subfields including molecular biology, psychiatry and mental health, biological psychiatry, immunology, and pulmonary and respiratory medicine.

The scientist's research topics include tryptophan and brain disorders, bipolar disorder and treatment, genomics and chromatin dynamics, schizophrenia research and treatment, histone deacetylase inhibitors research, epigenetics and DNA methylation, and immune cells in cancer.

Recent significant publications by Gerard Cagney include:

  • Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence (2020, JAMA Psychiatry)
  • Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer (2021, Science Advances)
  • Dysregulation of complement and coagulation pathways: emerging mechanisms in the development of psychosis (2021, Molecular Psychiatry)
  • Butyrate limits human natural killer cell effector function (2023, Scientific Reports)
  • A Quantitative Genetic Interaction Map of HIV Infection (2020, Molecular Cell)

Gerard Cagney collaborates frequently with a number of other researchers including:

  • Kieran Wynne
  • Melanie Föcking
  • David Cotter
  • David Mongan
  • Colm Healy

Their work has been published in several recurring venues such as:

  • Brain Behavior and Immunity
  • Schizophrenia Bulletin
  • Zenodo (CERN European Organization for Nuclear Research)
  • UNC Libraries
  • JAMA Psychiatry

Best Publications

  • A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

    Peter Uetz;Loic Giot;Gerard Cagney;Traci A. Mansfield

  • Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

    Nevan J. Krogan;Gerard Cagney;Gerard Cagney;Haiyuan Yu;Gouqing Zhong

  • Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

    Judith A. Coppinger;Gerard Cagney;Gerard Cagney;Sinead Toomey;Sinead Toomey;Thomas Kislinger;Thomas Kislinger

  • Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone

    Rongmin Zhao;Mike Davey;Ya-Chieh Hsu;Pia Kaplanek

  • Detailed identification of plasma proteins adsorbed on copolymer nanoparticles.

    Tommy Cedervall;Iseult Lynch;Martina Foy;Tord Berggård

  • Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II.

    Nevan J. Krogan;Minkyu Kim;Amy Tong;Ashkan Golshani

  • Global landscape of HIV-human protein complexes

    Stefanie Jäger;Peter Cimermancic;Peter Cimermancic;Natali Gulbahce;Natali Gulbahce;Jeffrey R. Johnson;Jeffrey R. Johnson;Jeffrey R. Johnson

  • RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.

    Nevan J. Krogan;Minkyu Kim;Seong Hoon Ahn;Guoqing Zhong

  • HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.

    Metka Lenassi;Gerard Cagney;Gerard Cagney;Maofu Liao;Tomaž Vaupotič

  • Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

    Frederic D. Bushman;Nirav Malani;Jason Fernandes;Jason Fernandes;Iván D'Orso;Iván D'Orso

  • High-Definition Macromolecular Composition of Yeast RNA-Processing Complexes

    Nevan J. Krogan;Wen-Tao Peng;Gerard Cagney;Mark D. Robinson

  • Large-scale functional analysis using peptide or protein arrays

    Alia Qureshi Emili;Gerard Cagney

  • Annexin-1 and Peptide Derivatives Are Released by Apoptotic Cells and Stimulate Phagocytosis of Apoptotic Neutrophils by Macrophages

    Michael Scannell;Michelle B. Flanagan;Andreas deStefani;Andreas deStefani;Kieran J. Wynne

  • A Panoramic View of Yeast Noncoding RNA Processing

    Wen Tao Peng;Mark D. Robinson;Sanie Mnaimneh;Nevan J. Krogan

  • Functional Organization of the S. cerevisiae Phosphorylation Network

    Dorothea Fiedler;Dorothea Fiedler;Hannes Braberg;Monika Mehta;Gal Chechik

  • De novo peptide sequencing and quantitative profiling of complex protein mixtures using mass-coded abundance tagging.

    Gerard Cagney;Andrew Emili

  • A Genetic Interaction Map of RNA Processing Factors Reveals Links Between Sem1/Dss1-Containing Complexes and mRNA Export and Splicing

    Gwendolyn M. Wilmes;Megan Bergkessel;Sourav Bandyopadhyay;Michael Shales

  • Proteasome Involvement in the Repair of DNA Double-Strand Breaks

    Nevan J. Krogan;Mandy H.Y. Lam;Jeffrey Fillingham;Michael-Christopher Keogh

  • Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

    Colm J. Ryan;Colm J. Ryan;Colm J. Ryan;Assen Roguev;Assen Roguev;Kristin Patrick;Kristin Patrick;Jiewei Xu;Jiewei Xu

  • Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation

    Gerard L Brien;Guillermo Gambero;David J O'Connell;Emilia Jerman

Frequent Co-Authors

Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Andrew Emili
Andrew Emili Boston University
Mary Cannon
Mary Cannon Royal College of Surgeons in Ireland
Jack Greenblatt
Jack Greenblatt University of Toronto
Lorna M. Lopez
Lorna M. Lopez University of California, Los Angeles
Peter Uetz
Peter Uetz Virginia Commonwealth University
Stanley Fields
Stanley Fields University of Washington
Stanley Zammit
Stanley Zammit University of Bristol
Denis C. Shields
Denis C. Shields University College Dublin
Bart P. F. Rutten
Bart P. F. Rutten Maastricht University Medical Centre

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