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Miguel A. R. B. Castanho

Miguel A. R. B. Castanho

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
13022
World Ranking
13103
National Ranking
52

Overview

Miguel A. R. B. Castanho is affiliated with the University of Lisbon in Portugal and has a research focus primarily in the fields of Biochemistry, Genetics and Molecular Biology, with a significant number of publications also related to Medicine.

The scientist's work spans several subfields, including Molecular Biology, Microbiology, Radiology, Nuclear Medicine and Imaging, Immunology, and Epidemiology. Their main research topics cover areas such as Antimicrobial Peptides and Activities, Chemical Synthesis and Analysis, RNA Interference and Gene Delivery, Monoclonal and Polyclonal Antibodies Research, HIV Research and Treatment, Biochemical and Structural Characterization, and Protein Hydrolysis and Bioactive Peptides.

Among their frequently published venues are:

  • Pharmaceutics
  • Biophysical Journal
  • Angewandte Chemie International Edition
  • FEBS Journal
  • International Journal of Molecular Sciences

Their recent papers include:

  • "Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System", 2020, Frontiers in Cell and Developmental Biology
  • "The Use of Antibody-Antibiotic Conjugates to Fight Bacterial Infections", 2022, Frontiers in Microbiology
  • "Antibodies for the Treatment of Brain Metastases, a Dream or a Reality?", 2020, Pharmaceutics
  • "Resazurin Reduction-Based Assays Revisited: Guidelines for Accurate Reporting of Relative Differences on Metabolic Status", 2023, Molecules
  • "The Challenge of Peptide Proteolytic Stability Studies: Scarce Data, Difficult Readability, and the Need for Harmonization", 2020, Angewandte Chemie International Edition

Frequent collaborators in the scientist's body of work include:

  • Vera Neves
  • Marco Cavaco
  • David Andreu
  • Javier Valle
  • Ana Salomé Veiga

Best Publications

  • Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

    Manuel N. Melo;Rafael Ferre;Miguel A. R. B. Castanho

  • From antimicrobial to anticancer peptides. a review

    Diana Gaspar;A. Salomé Veiga;Miguel A. R. B. Castanho

  • Cell-penetrating peptides and antimicrobial peptides: how different are they?

    Sónia Troeira Henriques;Manuel Nuno Melo;Miguel A. R. B. Castanho

  • An overview of the biophysical applications of atomic force microscopy.

    Nuno C. Santos;Miguel A.R.B. Castanho;Miguel A.R.B. Castanho

  • Receptors and routes of dengue virus entry into the host cells

    Christine Cruz-Oliveira;João Miguel Freire;Thaís M. Conceição;Luiza M. Higa

  • Quantifying molecular partition into model systems of biomembranes: an emphasis on optical spectroscopic methods.

    Nuno C. Santos;Manuel Prieto;Miguel A.R.B. Castanho

  • Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation

    Maria José Diógenes;Raquel B. Dias;Diogo M. Rombo;Hugo Vicente Miranda

  • Escherichia coli cell surface perturbation and disruption induced by antimicrobial peptides BP100 and pepR.

    Carla S. Alves;Manuel N. Melo;Henri G. Franquelim;Rafael Ferre

  • Amidated and Ibuprofen-Conjugated Kyotorphins Promote Neuronal Rescue and Memory Recovery in Cerebral Hypoperfusion Dementia Model.

    Sónia Sá Santos;Sara M. Santos;Antónia R. T. Pinto;Vasanthakumar G. Ramu

  • Arginine-rich self-assembling peptides as potent antibacterial gels

    Ana Salomé Veiga;Chomdao Sinthuvanich;Diana Gaspar;Henri G. Franquelim

  • Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

    Sónia Troeira Henriques;Sónia Troeira Henriques;Yen-Hua Huang;K. Johan Rosengren;Henri G. Franquelim

  • Teaching light scattering spectroscopy: the dimension and shape of tobacco mosaic virus.

    N. C. Santos;M. A. R. B. Castanho

  • Evaluation of Lipopolysaccharide aggregation by light scattering spectroscopy

    Nuno C. Santos;Ana C. Silva;Miguel A. R. B. Castanho;Miguel A. R. B. Castanho;João Martins-Silva

  • Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

    Inês M. Torcato;Yen-Hua Huang;Henri G. Franquelim;Diana Gaspar

  • Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins

    Filomena A. Carvalho;Fabiana A. Carneiro;Ivo C. Martins;Iranaia Assunção-Miranda

  • Biophysical characterization of polymyxin b interaction with LPS aggregates and membrane model systems

    Marco M. Domingues;Rita G. Inácio;José M. Raimundo;Miguel Martins

  • Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions

    Sónia Troeira Henriques;Yen-Hua Huang;Miguel A. R.B. Castanho;Luis A. Bagatolli

  • Fluorescence quenching data interpretation in biological systems. The use of microscopic models for data analysis and interpretation of complex systems.

    Miguel A.R.B Castanho;Manuel J.E Prieto

  • Translocation of beta-galactosidase mediated by the cell-penetrating peptide pep-1 into lipid vesicles and human HeLa cells is driven by membrane electrostatic potential.

    Sónia Troeira Henriques;Júlia Costa;Miguel A R B Castanho

  • Synergistic effects of the membrane actions of cecropin-melittin antimicrobial hybrid peptide BP100.

    Rafael Ferre;Manuel N. Melo;Ana D. Correia;Lidia Feliu

Frequent Co-Authors

David Andreu
David Andreu Pompeu Fabra University
Manuel Prieto
Manuel Prieto Instituto Superior Técnico
Isaura Tavares
Isaura Tavares University of Porto
Nuno C. Santos
Nuno C. Santos University of Porto
David J. Craik
David J. Craik University of Queensland
Gilda Tachedjian
Gilda Tachedjian Burnet Institute
Anne Moscona
Anne Moscona Columbia University
Benhur Lee
Benhur Lee Icahn School of Medicine at Mount Sinai
Marie-Isabel Aguilar
Marie-Isabel Aguilar Monash University
Norelle L. Daly
Norelle L. Daly James Cook University

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