His primary areas of study are Virology, Virus, Immunology, Antibody and Viral replication. His study in Virology is interdisciplinary in nature, drawing from both Immunization and Immunogenicity. His studies deal with areas such as Vaccinia, Recombinant virus and Mutant as well as Virus.
As a member of one scientific family, he mostly works in the field of Immunology, focusing on Respiratory tract and, on occasion, Pneumonitis and African Green Monkey. In his work, Pulmonary pathology is strongly intertwined with Antigen, which is a subfield of Antibody. Brian R. Murphy works mostly in the field of Viral replication, limiting it down to concerns involving Gene and, occasionally, Molecular biology.
His scientific interests lie mostly in Virology, Virus, Immunology, Influenza A virus and Viral replication. The Virology study combines topics in areas such as Antibody, Immunogenicity, Mutant and Recombinant DNA. Brian R. Murphy has included themes like Antigen, Immune system and Glycoprotein in his Antibody study.
His research investigates the connection between Virus and topics such as Recombinant virus that intersect with problems in Orthopoxvirus. His Influenza A virus research focuses on subjects like Hemagglutinin, which are linked to Neuraminidase. The Viral replication study which covers Flavivirus that intersects with Dengue fever.
His primary scientific interests are in Virology, Virus, Immunology, Dengue virus and Viral replication. His biological study spans a wide range of topics, including Attenuated vaccine and Immunogenicity. His study in Paramyxoviridae, Mononegavirales, Human Parainfluenza Virus, Orthomyxoviridae and Ebola virus is carried out as part of his studies in Virus.
His Dengue virus research is multidisciplinary, incorporating elements of Vero cell, Viremia and Untranslated region. His Viral replication research integrates issues from Mutation, Encephalitis and Mutant. His Neutralizing antibody research incorporates elements of Titer and Seroconversion.
Brian R. Murphy spends much of his time researching Virology, Virus, Immunology, Neutralizing antibody and Dengue virus. His work deals with themes such as Antibody and Immunogenicity, which intersect with Virology. His work investigates the relationship between Antibody and topics such as Glycoprotein that intersect with problems in Recombinant DNA, Neutralization, Antigen, Fc receptor and VP40.
His study looks at the relationship between Virus and fields such as Immunity, as well as how they intersect with chemical problems. His Viral replication research focuses on Encephalitis and how it relates to Attenuated vaccine and Infectivity. His Orthomyxoviridae study which covers Influenza A virus subtype H5N1 that intersects with DNA vaccination, Hemagglutinin and Viral Vaccine.
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A single amino acid in the PB2 gene of influenza A virus is a determinant of host range.
E K Subbarao;W London;B R Murphy.
Journal of Virology (1993)
A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice
Zhi Yong Yang;Wing Pui Kong;Yue Huang;Anjeanette Roberts.
An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus
Elisabetta Traggiai;Stephan Becker;Kanta Subbarao;Larissa Kolesnikova.
Nature Medicine (2004)
Safety and Immunogenicity Trial in Adult Volunteers of a Human Papillomavirus 16 L1 Virus-Like Particle Vaccine
Clayton D. Harro;Yuk Ying Susana Pang;Richard B.S. Roden;Allan Hildesheim.
Journal of the National Cancer Institute (2001)
Prospects for a dengue virus vaccine.
Stephen S. Whitehead;Joseph E. Blaney;Anna P. Durbin;Brian R. Murphy.
Nature Reviews Microbiology (2007)
EPIDEMIOLOGY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION IN WASHINGTON, D.C.II. INFECTION AND DISEASE WITH RESPECT TO AGE, IMMUNOLOGIC STATUS, RACE AND SEX
Robert H. Parrott;Hyun Wha Kim;Julita O. Arrobio;David S. Hodes.
American Journal of Epidemiology (1973)
Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant.
Ruth A. Karron;Deborah A. Buonagurio;Alice F. Georgiu;Stephen S. Whitehead.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Severe acute respiratory syndrome coronavirus spike protein expressed by attenuated vaccinia virus protectively immunizes mice
Himani Bisht;Anjeanette Roberts;Leatrice Vogel;Alexander Bukreyev.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization.
Brian R. Murphy;Alex V. Sotnikov;Lisa A. Lawrence;Steven M. Banks.
Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region.
Anna P. Durbin;Ruth A. Karron;Wellington Sun;David W. Vaughn.
American Journal of Tropical Medicine and Hygiene (2001)
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