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D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
36978
World Ranking
4926
National Ranking
365

Overview

Lars Zender is affiliated with the German Cancer Research Center in Germany. Their research spans diverse areas within medicine and biochemistry, genetics, and molecular biology, with a significant focus on oncology, molecular biology, and immunology, among other subfields.

Their work covers several topics, including:

  • Neuroendocrine Tumor Research Advances
  • Neuroblastoma Research and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Medical Imaging Techniques and Applications
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Cancer Mechanisms and Therapy

Lars Zender's research has been published in a variety of scientific venues, notably including:

  • Journal of Hepatology
  • Cancer Research
  • Cancers
  • Journal of Medicinal Chemistry
  • European Journal of Medicinal Chemistry

Frequent collaborators in their research include:

  • Christian la Fougère
  • Martina Hinterleitner
  • Stefan Laufer
  • Clemens Hinterleitner
  • Ulrich M. Lauer

Some recent notable papers authored or co-authored by Lars Zender are:

  • "NASH limits anti-tumour surveillance in immunotherapy-treated HCC," 2021, Nature
  • "The immunological and metabolic landscape in primary and metastatic liver cancer," 2021, Nature Reviews. Cancer
  • "Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations," 2021, Cancer Cell
  • "Advances in PET imaging of cancer," 2023, Nature Reviews. Cancer
  • "Platelet PD-L1 reflects collective intratumoral PD-L1 expression and predicts immunotherapy response in non-small cell lung cancer," 2021, Nature Communications

Best Publications

  • A microRNA component of the p53 tumour suppressor network

    Lin He;Xingyue He;Xingyue He;Lee P. Lim;Elisa de Stanchina;Elisa de Stanchina

  • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

    Wen Xue;Lars Zender;Cornelius Miething;Ross A. Dickins;Ross A. Dickins

  • Senescence of activated stellate cells limits liver fibrosis

    Valery Krizhanovsky;Monica Yon;Monica Yon;Ross A. Dickins;Stephen Hearn

  • A complex secretory program orchestrated by the inflammasome controls paracrine senescence

    Juan Carlos Acosta;Ana Banito;Torsten Wuestefeld;Athena Georgilis

  • Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

    Tae-Won Kang;Tetyana Yevsa;Norman Woller;Lisa Hoenicke

  • Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

    Lars. Zender;Mona S. Spector;Wen. Xue;Peer. Flemming

  • NASH limits anti-tumour surveillance in immunotherapy-treated HCC

    Dominik Pfister;Dominik Pfister;Nicolás Gonzalo Núñez;Roser Pinyol;Olivier Govaere

  • Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

    Selene Glück;Baptiste Guey;Muhammet Fatih Gulen;Katharina Wolter

  • T-helper-1-cell cytokines drive cancer into senescence

    Heidi Braumüller;Thomas Wieder;Ellen Brenner;Sonja Aßmann

  • mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

    Nicolás Herranz;Suchira Gallage;Massimiliano Mellone;Torsten Wuestefeld

  • Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis

    Stefanie U. Wiemann;Ande Satyanarayana;Martina Tsahuridu;Hans L. Tillmann

  • Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

    Tobias Eggert;Katharina Wolter;Juling Ji;Chi Ma

  • Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma.

    Michelle Z. Xu;Tzy-Jyun Yao;Nikki P. Y. Lee;Irene O. L. Ng

  • The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration

    Birgit Ritschka;Mekayla Storer;Alba Mas;Florian Heinzmann

  • Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

    Susanne Walz;Francesca Lorenzin;Jennifer Morton;Katrin E. Wiese

  • Caspase 8 small interfering RNA prevents acute liver failure in mice.

    Lars Zender;Sebastian Hütker;Christian Liedtke;Hans Ludger Tillmann

  • An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer

    Lars Zender;Wen Xue;Johannes Zuber;Camile P. Semighini

  • Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

    Eric T. Sawey;Maia Chanrion;Chunlin Cai;Guanming Wu

  • NOTCH1 mediates a switch between two distinct secretomes during senescence

    Matthew William Hoare;Yoko Ito;Tae-Won Kang;Michael Paul Weekes

  • Topoisomerase levels determine chemotherapy response in vitro and in vivo

    Darren J. Burgess;Jason Doles;Lars Zender;Wen Xue

Frequent Co-Authors

Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center
Mathias Heikenwalder
Mathias Heikenwalder German Cancer Research Center
Wen Xue
Wen Xue University of Massachusetts Chan Medical School
Josep M. Llovet
Josep M. Llovet University of Barcelona
Michael P. Manns
Michael P. Manns Hannover Medical School
Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Peter Schirmacher
Peter Schirmacher University Hospital Heidelberg
Thomas Wirth
Thomas Wirth University of Ulm
Scott Powers
Scott Powers Stony Brook University
Johannes Zuber
Johannes Zuber Research Institute of Molecular Pathology

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