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Christopher V. Nicchitta

Christopher V. Nicchitta

Duke University
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
11521
World Ranking
8890
National Ranking
3950

Christopher V. Nicchitta publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christopher V. Nicchitta sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 154 publications — 29th percentile

29% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christopher V. Nicchitta D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christopher V. Nicchitta sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 66 D-Index — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christopher V. Nicchitta is affiliated with Duke University in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research primarily spans molecular biology, cell biology, oncology, genetics, and cancer research with particular focus on the mechanisms underlying RNA and protein synthesis and their regulation in disease contexts.

Their work addresses key topics including:

  • RNA and protein synthesis mechanisms
  • RNA research and splicing
  • RNA modifications and cancer
  • Endoplasmic reticulum stress and disease
  • RNA regulation and disease
  • Cancer-related molecular pathways
  • Chronic lymphocytic leukemia research

Christopher V. Nicchitta has published in a range of scientific journals, with frequent contributions appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • RNA
  • UNC Libraries
  • Seminars in Cell and Developmental Biology
  • Proceedings of the National Academy of Sciences

Selected recent publications include:

  • Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules, 2021, RNA
  • Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane, 2020, Molecular & Cellular Proteomics
  • An emerging role for the endoplasmic reticulum in stress granule biogenesis, 2022, Seminars in Cell and Developmental Biology
  • Cooperative regulation of coupled oncoprotein synthesis and stability in triple-negative breast cancer by EGFR and CDK12/13, 2023, Proceedings of the National Academy of Sciences
  • Signal-noise metrics for RNA binding protein identification reveal broad spectrum protein-RNA interaction frequencies and dynamics, 2023, Nature Communications

The scientist collaborates frequently with several peers, including:

  • Qiang Chen
  • David W. Reid
  • JohnCarlo Kristofich
  • Molly M. Hannigan
  • Jessica R. Child

Christopher V. Nicchitta's research investigates molecular mechanisms associated with RNA interactions at the endoplasmic reticulum and their implications for cellular stress responses and cancer biology. Their work on stress granule biogenesis and proteomic profiling of translation mechanisms contributes to understanding how RNA and protein synthesis is regulated under physiological and pathological conditions.

Best Publications

  • HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

    Jeffrey J. Kovacs;Patrick J.M. Murphy;Stéphanie Gaillard;Xuan Zhao

  • Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90.

    Wanping Xu;Edward Mimnaugh;Meredith F.N. Rosser;Christopher Nicchitta

  • Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance

    Gregory LaMonte;Nisha Philip;Joseph Reardon;Joshua R. Lacsina

  • Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells.

    Brent Berwin;Justin P. Hart;Stuart Rice;Cecilia Gass

  • The DRiP hypothesis decennial: support, controversy, refinement and extension.

    Jonathan W. Yewdell;Christopher V. Nicchitta

  • Diversity and selectivity in mRNA translation on the endoplasmic reticulum

    David W. Reid;Christopher V. Nicchitta

  • Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation

    Christopher V. Nicchitta;Günter Blobel

  • Spermine. A regulator of mitochondrial calcium cycling.

    C V Nicchitta;J R Williamson

  • Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling.

    David W. Reid;Christopher V. Nicchitta

  • Rare codons regulate KRas oncogenesis.

    Benjamin L. Lampson;Nicole L.K. Pershing;Joseph A. Prinz;Joshua R. Lacsina

  • Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling

    Qi Quan Huang;Rudina Sobkoviak;Angela R. Jockheck-Clark;Bo Shi

  • Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes

    Rachel S. Lerner;Robert M. Seiser;Tianli Zheng;Patrick J. Lager

  • Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation

    Karen L. Soldano;Arif Jivan;Christopher V. Nicchitta;Daniel T. Gewirth

  • Interaction of endoplasmic reticulum chaperone GRP94 with peptide substrates is adenine nucleotide-independent

    Pamela A. Wearsch;Christopher V. Nicchitta

  • Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96.

    Christopher V Nicchitta

  • Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulum.

    Brook Pyhtila;Tianli Zheng;Patrick J. Lager;Jack D. Keene

  • Calreticulin Displays In Vivo Peptide-Binding Activity and Can Elicit CTL Responses Against Bound Peptides

    Smita Nair;Pamela A. Wearsch;Duane A. Mitchell;James J. Wassenberg

  • Membrane Topology Mapping of Vitamin K Epoxide Reductase by in Vitro Translation/Cotranslocation

    Jian-Ke Tie;Christopher V. Nicchitta;Gunnar von Heijne;Darrel W. Stafford

  • Interaction of TLR2 and TLR4 Ligands with the N-terminal Domain of Gp96 Amplifies Innate and Adaptive Immune Responses

    Tobias Warger;Norbert Hilf;Gerd Rechtsteiner;Philipp Haselmayer

  • Short Article HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

    Jeffrey J. Kovacs;Stéphanie Gaillard;Xuan Zhao;June-Tai Wu

Frequent Co-Authors

Günter Blobel
Günter Blobel Rockefeller University
Jonathan W. Yewdell
Jonathan W. Yewdell National Institute of Allergy and Infectious Diseases
John R. Williamson
John R. Williamson University of Pennsylvania
Jack D. Keene
Jack D. Keene Duke University
Salvatore V. Pizzo
Salvatore V. Pizzo Duke University
M. Zachary Rosenthal
M. Zachary Rosenthal Duke University
Shirish Shenolikar
Shirish Shenolikar Duke University
Jen-Tsan Chi
Jen-Tsan Chi Duke University
Jack R. Bennink
Jack R. Bennink National Institute of Allergy and Infectious Diseases
Subhash G. Vasudevan
Subhash G. Vasudevan Australian National University

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Best Scientists Citing Christopher V. Nicchitta

Richard Zimmermann

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Pramod K. Srivastava

Pramod K. Srivastava

University of Connecticut

Publications: 38

Leonard M. Neckers

Leonard M. Neckers

National Institutes of Health

Publications: 35

John R. Subjeck

John R. Subjeck

Roswell Park Cancer Institute

Publications: 34

Stuart K. Calderwood

Stuart K. Calderwood

Beth Israel Deaconess Medical Center

Publications: 31

Jonathan W. Yewdell

Jonathan W. Yewdell

National Institute of Allergy and Infectious Diseases

Publications: 31

Zihai Li

Zihai Li

The Ohio State University

Publications: 26

Gabriela Chiosis

Gabriela Chiosis

Memorial Sloan Kettering Cancer Center

Publications: 24

Tom A. Rapoport

Tom A. Rapoport

Harvard University

Publications: 24

Yair Argon

Yair Argon

Children's Hospital of Philadelphia

Publications: 22

Darrel W. Stafford

Darrel W. Stafford

University of North Carolina at Chapel Hill

Publications: 21

Tso-Pang Yao

Tso-Pang Yao

Duke University

Publications: 20

Paul Workman

Paul Workman

Institute of Cancer Research

Publications: 18

Johannes Buchner

Johannes Buchner

Technical University of Munich

Publications: 17

Ramanujan S. Hegde

Ramanujan S. Hegde

MRC Laboratory of Molecular Biology

Publications: 17

Patrick Matthias

Patrick Matthias

Friedrich Miescher Institute

Publications: 17

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