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Biology and Biochemistry

D-Index
52
Citations
9187
World Ranking
16733
National Ranking
6909

Overview

John R. Subjeck is affiliated with Roswell Park Cancer Institute in the United States and contributes to the fields of Medicine, Immunology, and Microbiology. Their research spans several subfields, including Oncology, Immunology, Psychiatry and Mental Health, Radiology, Nuclear Medicine and Imaging, and Biotechnology.

Their main research topics cover various aspects of cancer treatment and immune system interactions. These topics include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Cancer, Stress, Anesthesia, and Immune Response
  • Immune Cell Function and Interaction
  • Effects of Radiation Exposure
  • Cancer Research and Treatments
  • Heat shock proteins research

John R. Subjeck has published a number of papers in distinguished journals. Recent publications include:

  • Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation, 2020, Nature Communications
  • Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity, 2021, Journal for ImmunoTherapy of Cancer
  • Adrenergic Stress Constrains Development of Anti-tumor Immunity and Abscopal Responses Following Local Radiation, 2020, International Journal of Radiation Oncology*Biology*Physics
  • Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells, 2020, UNC Libraries
  • Reprogramming the tumor microenvironment with next-generation chaperone-based immunolytic agent for cancer immunotherapy, 2020, The Journal of Immunology

The primary publication venues for this scientist are diverse and include:

  • Nature Communications
  • Journal for ImmunoTherapy of Cancer
  • International Journal of Radiation Oncology*Biology*Physics
  • UNC Libraries
  • The Journal of Immunology

Frequent collaborators in their research work include:

  • Elizabeth A. Repasky
  • Wenjie Liu
  • Chunqing Guo
  • Guanxi Qiao
  • Bonnie L. Hylander

Best Publications

  • Stress protein systems of mammalian cells.

    J. R. Subjeck;Thung-Tai Shyy

  • Therapeutic cancer vaccines: past, present, and future.

    Chunqing Guo;Masoud H. Manjili;John R. Subjeck;Devanand Sarkar

  • The Hsp110 and Grp170 stress proteins: newly recognized relatives of the Hsp70s

    Douglas P. Easton;Yoshiyuki Kaneko;John R. Subjeck

  • Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation

    James J. Sciandra;John R. Subjeck;Christine S. Hughes

  • HSP110 PROTECTS HEAT-DENATURED PROTEINS AND CONFERS CELLULAR THERMORESISTANCE

    Hyun Ju Oh;Xing Chen;John R. Subjeck

  • Characterization of Heat Shock Protein 110 and Glucose-Regulated Protein 170 as Cancer Vaccines and the Effect of Fever-Range Hyperthermia on Vaccine Activity

    Xiang-Yang Wang;Latif Kazim;Elizabeth A. Repasky;John R. Subjeck

  • Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia

    Randy Burd;Thomas S. Dziedzic;Yan Xu;Michael A. Caligiuri

  • The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin.

    Hung Yun Lin;Patricia Masso-Welch;Yuan Pu Di;Jei Wei Cai

  • The chaperoning activity of hsp110. Identification of functional domains by use of targeted deletions.

    Hyun Ju Oh;Douglas Easton;Melanie Murawski;Yoshiyuki Kaneko

  • Identification of a Major Subfamily of Large hsp70-like Proteins through the Cloning of the Mammalian 110-kDa Heat Shock Protein

    Dongsin Lee-Yoon;Douglas Easton;Melanie Murawski;Randy Burd

  • Mammalian Hsp70 and Hsp110 proteins bind to RNA motifs involved in mRNA stability.

    Tamás Henics;Eszter Nagy;Hyun Ju Oh;Péter Csermely

  • Heat shock proteins as vaccine adjuvants in infections and cancer

    Brahm H. Segal;Xiang-Yang Wang;Carly G. Dennis;Richard Youn

  • Fever-Range Hyperthermia Enhances L-Selectin-Dependent Adhesion of Lymphocytes to Vascular Endothelium

    Wan-Chao Wang;Lorin M. Goldman;David M. Schleider;Michelle M. Appenheimer

  • Development of a recombinant HSP110-HER-2/neu vaccine using the chaperoning properties of HSP110.

    Masoud H. Manjili;Robert Henderson;Xiang-Yang Wang;Xing Chen

  • Scavenger Receptors: Emerging Roles in Cancer Biology and Immunology.

    Xiaofei Yu;Chunqing Guo;Paul B. Fisher;John R. Subjeck

  • HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice.

    Masoud H. Manjili;Xiang-Yang Wang;Xing Chen;Thomas Martin

  • Unfolding the Role of Large Heat Shock Proteins: New Insights and Therapeutic Implications

    Daming Zuo;John Subjeck;Xiang-Yang Wang

  • Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines

    Y. Wang;X.-Y. Wang;J. R. Subjeck;P. A. Shrikant

  • Resistance to Etoposide Induced by Three Glucose-regulated Stresses in Chinese Hamster Ovary Cells

    Christine S. Hughes;Jun Wen Shen;John R. Subjeck

  • Pattern Recognition Scavenger Receptor CD204 Attenuates Toll-like Receptor 4-induced NF-κB Activation by Directly Inhibiting Ubiquitination of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6

    Xiaofei Yu;Huanfa Yi;Chunqing Guo;Daming Zuo

Frequent Co-Authors

Elizabeth A. Repasky
Elizabeth A. Repasky Roswell Park Cancer Institute
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University
Hongxia Wang
Hongxia Wang Queensland University of Technology
Brahm H. Segal
Brahm H. Segal Roswell Park Cancer Institute
Richard S. Blumberg
Richard S. Blumberg Brigham and Women's Hospital
R. Balfour Sartor
R. Balfour Sartor University of North Carolina at Chapel Hill
Sean P. Colgan
Sean P. Colgan University of Colorado Anschutz Medical Campus
Stuart K. Calderwood
Stuart K. Calderwood Beth Israel Deaconess Medical Center
Lloyd Mayer
Lloyd Mayer Icahn School of Medicine at Mount Sinai
Atsushi Mizoguchi
Atsushi Mizoguchi Harvard University

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