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Atsushi Mizoguchi

Atsushi Mizoguchi

D-Index & Metrics

Immunology

D-Index
54
Citations
14124
World Ranking
3856
National Ranking
1769

Overview

Atsushi Mizoguchi is affiliated with Harvard University in the United States, focusing on research within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Immunology, Molecular Biology, Nephrology, Genetics, and Oncology.

Their research includes multiple aspects of immune system function and inflammation, particularly related to inflammatory bowel disease and studies on chitinases and chitosanases. Mizoguchi's main topics of study cover:

  • Studies on Chitinases and Chitosanases
  • Inflammatory Bowel Disease
  • Immune Cell Function and Interaction
  • Invertebrate Immune Response Mechanisms
  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Microscopic Colitis

Frequently publishing in journals such as Cells, Cytokine, Preprints.org, Diagnostics, and Oncology Letters, Mizoguchi has contributed to the academic discourse with several recent papers. Notable publications include:

  • "A Review of Selected IBD Biomarkers: From Animal Models to Bedside", 2021, Diagnostics
  • "Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation", 2024, Cells
  • "Altered serum profile of the interleukin-22 system in inflammatory bowel disease", 2020, Cytokine
  • "Recently updated role of Chitinase 3-like 1 on various cell types as a major infuencer of chronic inflammation", 2024, Preprints.org
  • "Diversity and shared T-cell receptor repertoire analysis in esophageal squamous cell carcinoma", 2021, Oncology Letters

Mizoguchi collaborates regularly with several co-authors, including Emiko Mizoguchi, Takayuki Sadanaga, Linda Nanni, Siyuan Wang, and Kei Fukami, reflecting a multi-disciplinary approach to their research themes.

Best Publications

  • IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

    Ken Sugimoto;Atsuhiro Ogawa;Atsuhiro Ogawa;Emiko Mizoguchi;Yasuyo Shimomura

  • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation.

    Atsushi Mizoguchi;Emiko Mizoguchi;Hidetoshi Takedatsu;Richard S Blumberg;Richard S Blumberg

  • Current Understanding of Dysbiosis in Disease in Human and Animal Models.

    Arianna K. DeGruttola;Daren Low;Atsushi Mizoguchi;Emiko Mizoguchi;Emiko Mizoguchi

  • A Case for Regulatory B Cells

    Atsushi Mizoguchi;Atul K. Bhan

  • The Transcription Factor T-bet Regulates Mucosal T Cell Activation in Experimental Colitis and Crohn's Disease

    M.F. Neurath;B. Weigmann;S. Finotto;J. Glickman

  • Human Neonatal Fc Receptor Mediates Transport of IgG into Luminal Secretions for Delivery of Antigens to Mucosal Dendritic Cells

    Masaru Yoshida;Steven M Claypool;Jessica S Wagner;Emiko Mizoguchi

  • Suppressive Role of B Cells in Chronic Colitis of T Cell Receptor α Mutant Mice

    Atsushi Mizoguchi;Emiko Mizoguchi;R. Neal Smith;Frederic I. Preffer

  • The Herbal Medicine Sho-saiko-to Inhibits Proliferation of Cancer Cell Lines by Inducing Apoptosis and Arrest at the G0/G1 Phase

    Hirohisa Yano;Atsushi Mizoguchi;Kazunori Fukuda;Makoto Haramaki

  • Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine

    Pietro G. Andres;Paul L. Beck;Emiko Mizoguchi;Atsushi Mizoguchi

  • Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice.

    Atsushi Mizoguchi;Emiko Mizoguchi;Chie Chiba;Atul K. Bhan

  • Animal Models of Inflammatory Bowel Disease

    Atsushi Mizoguchi

  • Regulatory role of mature B cells in A murine model of inflammatory bowel disease

    Emiko Mizoguchi;Atsushi Mizoguchi;Frederic I. Preffer;Atul K. Bhan

  • Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria

    Masaru Yoshida;Kanna Kobayashi;Timothy T. Kuo;Lynn Bry

  • Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice.

    Emiko Mizoguchi;Atsushi Mizoguchi;Hidetoshi Takedatsu;Elke Cario

  • Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease.

    A Mizoguchi;E Mizoguchi;C Chiba;G M Spiekermann

  • Clinical importance of IL-22 cascade in IBD.

    Atsushi Mizoguchi;Arisa Yano;Hidetomo Himuro;Yui Ezaki

  • Colitis in transgenic and knockout animals as models of human inflammatory bowel disease.

    Atul K. Bhan;Emiko Mizoguthi;R. Neal Smith;Atsushi Mizoguchi

  • Inflammatory bowel disease, past, present and future: lessons from animal models

    Atsushi Mizoguchi;Emiko Mizoguchi

  • Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

    Amlan Biswas;Yuen Joyce Liu;Liming Hao;Atsushi Mizoguchi

  • Induced Reactivity of Intestinal CD4+ T Cells with an Epithelial Cell Lectin, Galectin-4, Contributes to Exacerbation of Intestinal Inflammation

    Akira Hokama;Emiko Mizoguchi;Ken Sugimoto;Yasuyo Shimomura

  • The critical role of interleukin 4 but not interferon gamma in the pathogenesis of colitis in T-cell receptor α mutant mice

    Atsushi Mizoguchi;Emiko Mizoguchi;Atul K. Bhan

Frequent Co-Authors

Emiko Mizoguchi
Emiko Mizoguchi Kurume University
Atul K. Bhan
Atul K. Bhan Harvard University
Richard S. Blumberg
Richard S. Blumberg Brigham and Women's Hospital
Daniel K. Podolsky
Daniel K. Podolsky The University of Texas at Dallas
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Cox Terhorst
Cox Terhorst Beth Israel Deaconess Medical Center
Hans-Christian Reinecker
Hans-Christian Reinecker Harvard University
Wayne I. Lencer
Wayne I. Lencer Harvard University
Frederic I. Preffer
Frederic I. Preffer Harvard University

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