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Takashi Tsuruo
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Genetics and Molecular Biology
Japan
2024
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Medicine
Japan
2023

D-Index & Metrics

Discipline name D-Index World Ranking National Ranking Publications Citations
Medicine 136 1988 37 711 64995
Molecular Biology 134 164 14 588 57749

Takashi Tsuruo publications per year

The chart shows the history of publications by Takashi Tsuruo between 1968 and 2023, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Takashi Tsuruo published across 56 years, from 1968 to 2023, averaging 14.5 papers a year. Output peaked at 68 publications in 2023. 92 of the 814 publications appeared in the last two years.

No. of publications
20 40 60
Bar chart. Horizontal axis: year, 1968 to 2023. Vertical axis: number of publications, 0 to 68. Peak 68 publications in 2023. 1968: 2 publications 1969: 0 publications 1970: 2 publications 1971: 1 publication 1972: 2 publications 1973: 0 publications 1974: 3 publications 1975: 4 publications 1976: 0 publications 1977: 2 publications 1978: 2 publications 1979: 1 publication 1980: 8 publications 1981: 5 publications 1982: 4 publications 1983: 10 publications 1984: 9 publications 1985: 6 publications 1986: 13 publications 1987: 17 publications 1988: 23 publications 1989: 23 publications 1990: 29 publications 1991: 31 publications 1992: 26 publications 1993: 25 publications 1994: 28 publications 1995: 43 publications 1996: 30 publications 1997: 40 publications 1998: 47 publications 1999: 39 publications 2000: 30 publications 2001: 17 publications 2002: 35 publications 2003: 19 publications 2004: 29 publications 2005: 23 publications 2006: 11 publications 2007: 35 publications 2008: 20 publications 2009: 18 publications 2010: 9 publications 2011: 1 publication 2012: 0 publications 2013: 0 publications 2014: 0 publications 2015: 0 publications 2016: 0 publications 2017: 0 publications 2018: 0 publications 2019: 0 publications 2020: 0 publications 2021: 0 publications 2022: 24 publications 2023: 68 publications
1968 2023

814 publications in total across all disciplines

View publications per year as a table
Takashi Tsuruo: publications per year, 1968 to 2023
Year Publications
1968 2
1969 0
1970 2
1971 1
1972 2
1973 0
1974 3
1975 4
1976 0
1977 2
1978 2
1979 1
1980 8
1981 5
1982 4
1983 10
1984 9
1985 6
1986 13
1987 17
1988 23
1989 23
1990 29
1991 31
1992 26
1993 25
1994 28
1995 43
1996 30
1997 40
1998 47
1999 39
2000 30
2001 17
2002 35
2003 19
2004 29
2005 23
2006 11
2007 35
2008 20
2009 18
2010 9
2011 1
2012 0
2013 0
2014 0
2015 0
2016 0
2017 0
2018 0
2019 0
2020 0
2021 0
2022 24
2023 68
Total 814
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Takashi Tsuruo publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Takashi Tsuruo sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 53 bars. Horizontal axis: publications, 47–56 to 564+. Vertical axis: number of scientists, 0 to 177. Most scientists, 177, have 117–126 publications. The last bar groups every scientist with 564 publications or more. The highlighted bar, 564+ publications, is where this scientist sits. 47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47–56 publications 564+

This scientist: 588 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

View publications distribution as a table
Number of Molecular Biology scientists by publication count, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
Publications Scientists This scientist
47–56 7
57–66 17
67–76 65
77–86 90
87–96 125
97–106 131
107–116 162
117–126 177
127–136 158
137–146 158
147–156 146
157–166 159
167–176 131
177–186 110
187–196 112
197–206 100
207–216 89
217–226 98
227–236 74
237–246 72
247–256 63
257–266 53
267–276 54
277–286 49
287–296 52
297–306 43
307–316 46
317–326 41
327–336 42
337–346 31
347–356 28
357–366 29
367–376 26
377–386 24
387–396 24
397–406 14
407–416 13
417–426 20
427–436 12
437–446 20
447–456 11
457–466 10
467–476 14
477–486 14
487–496 10
497–506 13
507–516 13
517–526 2
527–536 4
537–546 6
547–556 8
557–563 6
564+ 100 588
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Takashi Tsuruo D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Takashi Tsuruo sits on this spectrum.

No. of scientists
25 50 75 100 125
Bar chart with 54 bars. Horizontal axis: D-Index, 40–41 to 145+. Vertical axis: number of scientists, 0 to 131. Most scientists, 131, have 64–65 D-Index. The last bar groups every scientist with 145 D-Index or more. The highlighted bar, 134–135 D-Index, is where this scientist sits. 40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40–41 D-Index 145+

This scientist: 134 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

View D-Index distribution as a table
Number of Molecular Biology scientists by D-index, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
D-Index Scientists This scientist
40–41 36
42–43 101
44–45 115
46–47 121
48–49 118
50–51 130
52–53 106
54–55 116
56–57 113
58–59 129
60–61 120
62–63 105
64–65 131
66–67 95
68–69 97
70–71 106
72–73 83
74–75 89
76–77 77
78–79 70
80–81 73
82–83 60
84–85 48
86–87 45
88–89 50
90–91 31
92–93 51
94–95 43
96–97 38
98–99 39
100–101 41
102–103 29
104–105 33
106–107 35
108–109 20
110–111 38
112–113 19
114–115 28
116–117 13
118–119 23
120–121 16
122–123 15
124–125 11
126–127 21
128–129 7
130–131 13
132–133 14
134–135 17 134
136–137 9
138–139 8
140–141 16
142–143 7
144 7
145+ 100
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Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Molecular biology, Apoptosis, Cell culture, Cancer research and Cell biology are his primary areas of study. His Molecular biology research is multidisciplinary, incorporating elements of Cell, Camptothecin, Telomere, Monoclonal antibody and Telomerase reverse transcriptase. Takashi Tsuruo has researched Apoptosis in several fields, including Proteases and Enzyme.

His Cell culture research integrates issues from In vitro, Gene expression, Cancer cell, Immunology and Telomerase. His work deals with themes such as ASK1, Mitogen-activated protein kinase kinase, Cytotoxicity, Kinase and MAP kinase kinase kinase, which intersect with Cancer research. In his work, Serine/threonine-specific protein kinase and Phosphorylation cascade is strongly intertwined with Cyclin-dependent kinase 1, which is a subfield of Cell biology.

His most cited work include:

  • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues (2446 citations)
  • Overcoming of Vincristine Resistance in P388 Leukemia in Vivo and in Vitro through Enhanced Cytotoxicity of Vincristine and Vinblastine by Verapamil (1343 citations)
  • Modulation of Akt kinase activity by binding to Hsp90 (809 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Cancer research, Cell culture, P-glycoprotein and In vitro. The Molecular biology study combines topics in areas such as Apoptosis, Biochemistry, DNA, Cell biology and Monoclonal antibody. His research in Cancer research intersects with topics in Endocrinology, Cancer cell, Internal medicine, Metastasis and Kinase.

His Cell culture study which covers Camptothecin that intersects with Topoisomerase. His P-glycoprotein study integrates concerns from other disciplines, such as Blood–brain barrier, Cyclosporin a, Immunology and Pharmacology. Takashi Tsuruo combines subjects such as Vincristine, Stereochemistry and In vivo with his study of In vitro.

He most often published in these fields:

  • Molecular biology (47.75%)
  • Cancer research (35.89%)
  • Cell culture (32.05%)

What were the highlights of his more recent work (between 2001-2011)?

  • Cell biology (27.88%)
  • Cancer research (35.89%)
  • Molecular biology (47.75%)

In recent papers he was focusing on the following fields of study:

Takashi Tsuruo focuses on Cell biology, Cancer research, Molecular biology, Biochemistry and Pharmacology. His Cell biology study frequently draws connections between adjacent fields such as Apoptosis. His work in Cancer research tackles topics such as Cancer cell which are related to areas like Metastasis.

His study on Molecular biology also encompasses disciplines like

  • Transfection which connect with Regulation of gene expression,
  • Cell culture which is related to area like Organic cation transport proteins. His research integrates issues of P-glycoprotein, Drug resistance, Multiple drug resistance, Chemotherapy and Efflux in his study of Pharmacology. His P-glycoprotein study deals with Immunology intersecting with Neurotoxicity.

Between 2001 and 2011, his most popular works were:

  • C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. (389 citations)
  • C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. (389 citations)
  • Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization. (302 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His primary scientific interests are in Cell biology, Molecular biology, Protein kinase B, Cancer research and Biochemistry. Takashi Tsuruo has included themes like Cyclin-dependent kinase 1 and Enzyme in his Cell biology study. His Molecular biology research is multidisciplinary, incorporating perspectives in Cell culture, Transfection, Targeted disruption, Efflux and Neonatal lethality.

His study in Protein kinase B is interdisciplinary in nature, drawing from both PI3K/AKT/mTOR pathway and Kinase, Kinase activity. His research investigates the link between Kinase and topics such as Dephosphorylation that cross with problems in 7-hydroxystaurosporine, Cytotoxicity, In vivo, Caspase and Ceramide. His studies deal with areas such as Endocrinology, Apoptosome, Cancer cell, Apoptosis and Internal medicine as well as Cancer research.

Best Publications

  • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

    Franz Thiebaut;Takashi Tsuruo;Hirofumi Hamada;Michael M. Gottesman

  • Overcoming of Vincristine Resistance in P388 Leukemia in Vivo and in Vitro through Enhanced Cytotoxicity of Vincristine and Vinblastine by Verapamil

    Takashi Tsuruo;Harumi Iida;Shigeru Tsukagoshi;Yoshio Sakurai

  • Modulation of Akt kinase activity by binding to Hsp90

    Saori Sato;Naoya Fujita;Takashi Tsuruo

  • A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

    Akiko Saito;Takashi Yamashita;Yukiyasu Mariko;Yasuhito Nosaka

  • Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors

    Takashi Tsuruo;Harumi Iida;Shigeru Tsukagoshi;Yoshio Sakurai

  • Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

    Rika Hoshino;Yuji Chatani;Takao Yamori;Takashi Tsuruo;Takashi Tsuruo

  • Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein.

    Franz Thiebaut;Takashi Tsuruo;Hirofumi Hamada;Michael M. Gottesman

  • Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

    Hirofumi Hamada;Takashi Tsuruo

  • Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion

    Thomas C. Hamilton;Margaret A. Winker;Karen G. Louie;Gerald Batist

  • Clinical Significance of Multidrug Resistance P-Glycoprotein Expression on Acute Nonlymphoblastic Leukemia Cells at Diagnosis

    Lydia Campos;Denis Guyotat;Eric Archimbaud;Pascale Calmard-Oriol

  • Tissue Distribution of P-Glycoprotein Encoded by a Multidrug-resistant Gene as Revealed by a Monoclonal Antibody, MRK 16

    Isamu Sugawara;Iyo Kataoka;Yasuyuki Morishita;Hirofumi Hamada

  • C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance.

    Yasuo Imai;Minoru Nakane;Kumie Kage;Satomi Tsukahara

  • Circumvention of Vincristine and Adriamycin Resistance in Vitro and in Vivo by Calcium Influx Blockers

    Takashi Tsuruo;Harumi Iida;Makiko Nojiri;Shigeru Tsukagoshi

  • Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation

    Ikuo Saiki;Junya Yoneda;Ichiro Azuma;Hideji Fujii

  • Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.

    H Hamada;T Tsuruo

  • Domain Mapping Studies Reveal That the M Domain of hsp90 Serves as a Molecular Scaffold to Regulate Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase and NO Release

    Jason Fontana;David Fulton;Yan Chen;Todd A. Fairchild

  • Involvement of 14‐3‐3 proteins in nuclear localization of telomerase

    Hiroyuki Seimiya;Hiroyuki Seimiya;Hiroko Sawada;Yukiko Muramatsu;Mayuko Shimizu

  • Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production

    Shinya Dohgu;Fuyuko Takata;Atsushi Yamauchi;Shinsuke Nakagawa

  • Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

    Mika Shimonaka;Mika Shimonaka;Koko Katagiri;Toshinori Nakayama;Naoya Fujita

  • Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

    Naoya Fujita;Saori Sato;Kazuhiro Katayama;Takashi Tsuruo;Takashi Tsuruo

Frequent Co-Authors

Mikihiko Naito
Mikihiko Naito University of Tokyo
Naoya Fujita
Naoya Fujita Japanese Foundation For Cancer Research
Hirofumi Hamada
Hirofumi Hamada Sapporo Medical University
Yoshikazu Sugimoto
Yoshikazu Sugimoto Keio University
Saburo Sone
Saburo Sone University of Tokushima
Isamu Sugawara
Isamu Sugawara Saitama Medical University
Yukinari Kato
Yukinari Kato Tohoku University
Michael M. Gottesman
Michael M. Gottesman National Institutes of Health
Ira Pastan
Ira Pastan Center for Cancer Research
Shigeo Mori
Shigeo Mori University of Tokyo

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Related Online Degrees & Career Pathways

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Additionally, many professionals from backgrounds such as education are discovering new opportunities by making a teacher to slp (speech-language pathologist) career change—a transition supported by specialized online degree programs.

Best Scientists Citing Takashi Tsuruo

Takashi Tsuruo

Takashi Tsuruo

Japanese Foundation For Cancer Research

Publications: 136

Michael M. Gottesman

Michael M. Gottesman

National Institutes of Health

Publications: 108

Ira Pastan

Ira Pastan

Center for Cancer Research

Publications: 98

Yukinari Kato

Yukinari Kato

Tohoku University

Publications: 80

Yoshikazu Sugimoto

Yoshikazu Sugimoto

Keio University

Publications: 77

Saburo Sone

Saburo Sone

University of Tokushima

Publications: 67

Tetsuya Terasaki

Tetsuya Terasaki

Tohoku University

Publications: 65

Mika K. Kaneko

Mika K. Kaneko

Tohoku University

Publications: 65

Susan E. Bates

Susan E. Bates

Columbia University

Publications: 64

Jos H. Beijnen

Jos H. Beijnen

Utrecht University

Publications: 60

Suresh V. Ambudkar

Suresh V. Ambudkar

National Institutes of Health

Publications: 60

Naoya Fujita

Naoya Fujita

Japanese Foundation For Cancer Research

Publications: 55

Yuichi Sugiyama

Yuichi Sugiyama

University of Tokyo

Publications: 54

Minoru Yoshida

Minoru Yoshida

University of Tokyo

Publications: 46

Yusuke Nakamura

Yusuke Nakamura

National Institutes of Biomedical Innovation, Health and Nutrition

Publications: 45

Victor Ling

Victor Ling

BC Cancer Research Centre

Publications: 44

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