Brian C. Schutte

Overview

Best Publications

• TLR4 mutations are associated with endotoxin hyporesponsiveness in humans.

  Nancy C. Arbour;Eva Lorenz;Brian C. Schutte;Joseph Zabner

  2593
  Citations

• Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes.

  Shinji Kondo;Brian C. Schutte;Rebecca J. Richardson;Bryan C. Bjork

  1051
  Citations

• Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate.

  Theresa M. Zucchero;Margaret E. Cooper;Brion S. Maher;Sandra Daack-Hirsch

  775
  Citations

• Discovery of five conserved β-defensin gene clusters using a computational search strategy

  Brian C. Schutte;Joseph P. Mitros;Jennifer A. Bartlett;Jesse D. Walters

  666
  Citations

• Disruption of an AP-2 alpha binding site in an IRF6 enhancer is associated with cleft lip

  Fedik Rahimov;Mary L Marazita;Axel Visel;Margaret E Cooper

  587
  Citations

• The Many Faces and Factors of Orofacial Clefts

  Brian C. Schutte;Jeffrey C. Murray

  484
  Citations

• Discovery of new human β-defensins using a genomics-based approach

  Hong Peng Jia;Brian C. Schutte;Andreas Schudy;Rose Linzmeier

  415
  Citations

• Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 ( Irf6 )

  Christopher R. Ingraham;Akira Kinoshita;Shinji Kondo;Baoli Yang

  394
  Citations

• Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation.

  Lide Liu;Lina Wang;Hong Peng Jia;Chengquan Zhao

  350
  Citations

• Mutations in NBEAL2 , encoding a BEACH protein, cause gray platelet syndrome

  Walter H A Kahr;Jesse Hinckley;Ling Li;Hansjörg Schwertz

  292
  Citations

• Variable airway responsiveness to inhaled lipopolysaccharide.

  J N Kline;J D Cowden;G W Hunninghake;B C Schutte

  284
  Citations

• β-Defensins in Lung Host Defense

  Brian C. Schutte;Paul B. McCray

  277
  Citations

• Cleft palate: players, pathways, and pursuits

  Jeffrey C. Murray;Brian C. Schutte

  236
  Citations

• Dominant mutations in GRHL3 cause Van der Woude syndrome and disrupt oral periderm development

  Myriam Peyrard-Janvid;Elizabeth J. Leslie;Youssef A. Kousa;Tiffany L. Smith

  223
  Citations

• The DNA rearrangement associated with facioscapulohumeral muscular dystrophy involves a heterochromatin-associated repetitive element: Implications for a role of chromatin structure in the pathogenesis of the disease

  Winokur St;Bengtsson U;Feddersen J;Mathews Kd

  207
  Citations

• Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci

  Elizabeth J. Leslie;Margaret A. Taub;Huan Liu;Huan Liu;Karyn Meltz Steinberg

  171
  Citations

• A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer.

  Martin J Tymms;Annie Yn Ng;Ross S Thomas;Brian C Schutte

  171
  Citations

• recA protein-promoted ATP hydrolysis occurs throughout recA nucleoprotein filaments.

  S.L. Brenner;R.S. Mitchell;S.W. Morrical;S.K. Neuendorf

  160
  Citations

• Prevalence and nonrandom distribution of exonic mutations in interferon regulatory factor 6 in 307 families with Van der Woude syndrome and 37 families with popliteal pterygium syndrome.

  Renata L L Ferreira de Lima;Sarah A Hoper;Michella Ghassibe;Margaret E Cooper

  160
  Citations

• Defective expression of p56lck in an infant with severe combined immunodeficiency.

  F D Goldman;Z K Ballas;B C Schutte;J Kemp

  148
  Citations