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Steve Gerondakis

Steve Gerondakis

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13502
World Ranking
10818
National Ranking
290

Overview

Steve Gerondakis is affiliated with Monash University in Australia and has contributed to multiple research publications primarily within the fields of Immunology and Microbiology, as well as Medicine.

The scientist's work focuses on key topics including:

  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses

Gerondakis' recent papers cover aspects of immune response regulation and cell activation. Notable publications include:

  • c-Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in mice (2021), European Journal of Immunology
  • c-Rel Is Required for IL-33-Dependent Activation of ILC2s (2021), Frontiers in Immunology
  • c-Rel is required for IL-33-dependent activation of ILC2s (2021), bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors in this research include:

  • Thomas S. Fulford
  • Raelene J. Grumont
  • Sebastian Scheer
  • Colby Zaph
  • Aidil Zaini

The scientist has published predominantly in venues such as:

  • European Journal of Immunology
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Gerondakis' research extends into subfields including Immunology and Surgery, with a particular concentration on immune mechanisms and cellular pathways fundamental to immune system function and related disorders.

Best Publications

  • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

    Frank Köntgen;Raelene J. Grumont;Raelene J. Grumont;Andreas Strasser;Donald Metcalf

  • Genetic approaches in mice to understand Rel/NF-κB and IκB function: transgenics and knockouts

    Steve Gerondakis;Mathis Grossmann;Yukio Nakamura;Thomas Pohl

  • Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

    Graeme I. Lancaster;Graeme I. Lancaster;Katherine G. Langley;Katherine G. Langley;Nils Anton Berglund;Helene L. Kammoun

  • Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas

    Jerry M. Adams;Steven Gerondakis;Elizabeth Webb;Lynn M. Corcoran

  • Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models

    S Gerondakis;R Grumont;R Gugasyan;L Wong

  • Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.

    Jan Bohuslav;Vladimir V. Kravchenko;Graham C.N. Parry;Jonathan H. Erlich

  • Roles of the NF-κB Pathway in Lymphocyte Development and Function

    Steve Gerondakis;Ulrich Siebenlist

  • B Lymphocytes Differentially Use the Rel and Nuclear Factor κB1 (NF-κB1) Transcription Factors to Regulate Cell Cycle Progression and Apoptosis in Quiescent and Mitogen-activated Cells

    Raelene J. Grumont;Ian J. Rourke;Lorraine A. O'Reilly;Andreas Strasser

  • Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1

    Kate L Jeffrey;Kate L Jeffrey;Tilman Brummer;Michael S Rolph;Michael S Rolph;Sue M Liu;Sue M Liu

  • c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells

    Iwao Isomura;Stephanie Palmer;Raelene J. Grumont;Karen L Bunting

  • Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB.

    Raelene J. Grumont;Steve Gerondakis

  • The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.

    Mathis Grossmann;Lorraine A. O'Reilly;Raffi Gugasyan;Andreas Strasser

  • THE REGULATION AND ROLES OF REL/NF-KAPPA B TRANSCRIPTION FACTORS DURING LYMPHOCYTE ACTIVATION

    Steve Gerondakis;Raelene Grumont;Ian Rourke;Mathis Grossmann

  • Distinct roles for the NF-κB1 (p50) and c-Rel transcription factors in inflammatory arthritis

    Ian K. Campbell;Steve Gerondakis;Kristy O’Donnell;Ian P. Wicks

  • Coordinating TLR-activated signaling pathways in cells of the immune system

    Ashish Banerjee;Steve Gerondakis

  • C-Rel Regulates Interleukin 12 P70 Expression in Cd8+ Dendritic Cells by Specifically Inducing p35 Gene Transcription

    Raelene Grumont;Hubertus Hochrein;Meredith O'Keeffe;Raffi Gugasyan

  • Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

    Ashish Banerjee;Raffi Gugasyan;Martin McMahon;Steve Gerondakis

  • The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

    Mathis Grossmann;Donald Metcalf;Julie Merryfull;Amer Beg

  • Absence of NF-κB subunit p50 improves heart failure after myocardial infarction

    Stefan Frantz;Kai Hu;Barbara Bayer;Steve Gerondakis

  • Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor

    Steven Demetrious Gerondakis;Andreas Strasser;Donald Metcalf;George Grigoriadis

Frequent Co-Authors

Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Lorraine A. O'Reilly
Lorraine A. O'Reilly Walter and Eliza Hall Institute of Medical Research
Ranjeny Thomas
Ranjeny Thomas University of Queensland
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Ian P. Wicks
Ian P. Wicks Walter and Eliza Hall Institute of Medical Research
Marc Pellegrini
Marc Pellegrini Walter and Eliza Hall Institute of Medical Research
Elissa K. Deenick
Elissa K. Deenick Garvan Institute of Medical Research
Meredith O'Keeffe
Meredith O'Keeffe Monash University
Mark A. Febbraio
Mark A. Febbraio Monash University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research

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