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Meredith O'Keeffe

Meredith O'Keeffe

D-Index & Metrics

Immunology

D-Index
46
Citations
12260
World Ranking
4573
National Ranking
198

Overview

Meredith O'Keeffe is affiliated with Monash University in Australia and has a research focus primarily in immunology and microbiology. Their work spans 47 publications in these broad fields, with notable contributions in subfields including immunology, infectious diseases, clinical psychology, molecular biology, and microbiology.

O'Keeffe's research addresses several core topics within immunology, including T-cell and B-cell immunology, immunotherapy and immune responses, immune cell function and interaction, interferon and immune responses, immune response and inflammation, viral infections and vectors, and antimicrobial peptides and activities.

They have published extensively in various scientific venues, with frequent contributions to The Journal of Immunology (five publications), bioRxiv (Cold Spring Harbor Laboratory) (three publications), Immunity (two publications), iScience (two publications), and The EMBO Journal (one publication).

Key recent papers authored or coauthored by O'Keeffe include:

  • Termination of STING responses is mediated via ESCRT -dependent degradation, 2023, The EMBO Journal
  • Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development, 2021, Immunity
  • RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells, 2020, eLife
  • Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations, 2022, Frontiers in Immunology
  • Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection, 2024, Immunity

Their collaborative work often involves a number of frequent coauthors, including Ee Shan Pang, Timothy Patton, Katherine R. Balka, Peck Szee Tan, and Benjamin T. Kile, reflecting ongoing partnerships in immune-related research.

Best Publications

  • Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo

    Shalin H. Naik;Priyanka Sathe;Priyanka Sathe;Hae Young Park;Hae Young Park;Donald Metcalf

  • Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

    Shalin H Naik;Shalin H Naik;Donald Metcalf;Annemarie van Nieuwenhuijze;Ian Wicks

  • Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets.

    Hubertus Hochrein;Ken Shortman;David Vremec;Bernadette M Scott

  • Quantitative proteomics reveals subset-specific viral recognition in dendritic cells.

    Christian A. Luber;Jürgen Cox;Henning Lauterbach;Ben Fancke

  • Cutting Edge: Generation of Splenic CD8+ and CD8− Dendritic Cell Equivalents in Fms-Like Tyrosine Kinase 3 Ligand Bone Marrow Cultures

    Shalin H. Naik;Anna I Proietto;Nicholas S. Wilson;Aleksandar Dakic

  • Herpes simplex virus type-1 induces IFN-α production via Toll-like receptor 9-dependent and -independent pathways

    Hubertus Hochrein;Beatrix Schlatter;Meredith O'Keeffe;Cornelia Wagner

  • Mouse Plasmacytoid Cells Long-lived Cells, Heterogeneous in Surface Phenotype and Function, that Differentiate Into CD8+ Dendritic Cells Only after Microbial Stimulus

    Meredith O’Keeffe;Hubertus Hochrein;David Vremec;Irina Caminschi

  • The development, maturation, and turnover rate of mouse spleen dendritic cell populations

    Arun T. Kamath;Joanne Pooley;Meredith A. O’Keeffe;David Vremec

  • Interleukin (Il)-4 Is a Major Regulatory Cytokine Governing Bioactive IL-12 Production by Mouse and Human Dendritic Cells

    Hubertus Hochrein;Meredith O'Keeffe;Thomas Luft;Stéphane Vandenabeele

  • Mouse CD8α+ DCs and human BDCA3+ DCs are major producers of IFN-λ in response to poly IC

    Henning Lauterbach;Barbara Bathke;Stefanie Gilles;Claudia Traidl-Hoffmann

  • Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

    Louise J. Young;Nicholas S. Wilson;Petra Schnorrer;Petra Schnorrer;Anna I Proietto;Anna I Proietto

  • Dendritic cell subsets.

    Christophe Macri;Ee Shan Pang;Timothy Patton;Meredith O'Keeffe

  • The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells.

    Lynn Corcoran;Isabel Ferrero;David Vremec;Karen Lucas

  • Development of thymic and splenic dendritic cell populations from different hemopoietic precursors.

    Li Wu;Angela D'Amico;Angela D'Amico;Hubertus Hochrein;Hubertus Hochrein;Meredith O'Keeffe;Meredith O'Keeffe

  • Dendritic cell precursor populations of mouse blood: identification of the murine homologues of human blood plasmacytoid pre-DC2 and CD11c+ DC1 precursors.

    Meredith O'Keeffe;Hubertus Hochrein;David Vremec;Bernadette Maree Scott

  • Effects of administration of progenipoietin 1, Flt-3 ligand, granulocyte colony-stimulating factor, and pegylated granulocyte-macrophage colony-stimulating factor on dendritic cell subsets in mice

    Meredith O'Keeffe;Hubertus Hochrein;Hubertus Hochrein;Hubertus Hochrein;David Vremec;David Vremec;David Vremec;Joanne Pooley

  • CpG-DNA aided cross-presentation of soluble antigens by dendritic cells.

    Tobias Maurer;Antje Heit;Hubertus Hochrein;Franziska Ampenberger

  • C-Rel Regulates Interleukin 12 P70 Expression in Cd8+ Dendritic Cells by Specifically Inducing p35 Gene Transcription

    Raelene Grumont;Hubertus Hochrein;Meredith O'Keeffe;Raffi Gugasyan

  • Human dendritic cell subsets and function in health and disease.

    Meredith Anne O'Keeffe;Meredith Anne O'Keeffe;Wai Hong Mok;Kristen J Radford

  • Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection.

    Christofer Samuelsson;Jürgen Hausmann;Henning Lauterbach;Michaela Schmidt

  • DEC-205 is a cell surface receptor for CpG oligonucleotides

    Mireille H Lahoud;Fatma Ahmet;Fatma Ahmet;Jian-Guo Zhang;Simone Meuter;Simone Meuter

Frequent Co-Authors

Ken Shortman
Ken Shortman Walter and Eliza Hall Institute of Medical Research
Hubertus Hochrein
Hubertus Hochrein Technical University of Munich
David Vremec
David Vremec Walter and Eliza Hall Institute of Medical Research
Irina Caminschi
Irina Caminschi Monash University
Li Wu
Li Wu Tsinghua University
Jose A. Villadangos
Jose A. Villadangos University of Melbourne
William R. Heath
William R. Heath University of Melbourne
Jian-Guo Zhang
Jian-Guo Zhang Beijing Institute for Brain Disorders
Andrew M. Lew
Andrew M. Lew Walter and Eliza Hall Institute of Medical Research
Paul J. Hertzog
Paul J. Hertzog Hudson Institute of Medical Research

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