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Immunology

D-Index
98
Citations
53919
World Ranking
769
National Ranking
68

Research.com Recognitions

  • 2019 - Fellow of the Royal Society, United Kingdom

Overview

Caetano Reis e Sousa is affiliated with The Francis Crick Institute in the United Kingdom. Their research focuses primarily on immunology and microbiology, with significant contributions to medicine. The scientist's work spans several subfields including immunology, molecular biology, oncology, infectious diseases, and biomedical engineering.

Their research topics emphasize immunotherapy and immune responses, T-cell and B-cell immunology, and immune cell function and interaction. Additional areas of interest include SARS-CoV-2 detection and testing, interferon and immune responses, biosensors and analytical detection, as well as CAR-T cell therapy research.

Selected recent publications by Caetano Reis e Sousa include:

  • "Dendritic Cells Revisited," 2021, Annual Review of Immunology
  • "Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade," 2020, Immunity
  • "The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens," 2020, Nature Immunology
  • "An isoform of Dicer protects mammalian stem cells against multiple RNA viruses," 2021, Science
  • "Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity," 2021, Cell

Frequent co-authors collaborating with Caetano Reis e Sousa include Ana Cardoso, Neil C. Rogers, Michael D. Buck, Johnathan Canton, and Bruno Frederico.

Regarding publication venues, their work has been published multiple times in:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Immunity
  • Nature Immunology
  • Science
  • The EMBO Journal

Caetano Reis e Sousa was elected a Fellow of the Royal Society in the United Kingdom in 2019.

Best Publications

  • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

    Hiroki Kato;Osamu Takeuchi;Shintaro Sato;Mitsutoshi Yoneyama

  • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

    Sandra S. Diebold;Tsuneyasu Kaisho;Hiroaki Hemmi;Shizuo Akira

  • RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5' Phosphates

    Andreas Pichlmair;Oliver Schulz;Choon Ping Tan;Tanja I. Näslund

  • NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control

    Jan P. Böttcher;Eduardo Bonavita;Probir Chakravarty;Hanna Blees

  • Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

    Salomé LeibundGut-Landmann;Olaf Groß;Matthew J Robinson;Fabiola Osorio

  • Dendritic cells in a mature age.

    Caetano Reis e Sousa

  • Toll-like receptor 3 promotes cross-priming to virus-infected cells

    Oliver Schulz;Sandra S. Diebold;Margaret Chen;Tanja I. Näslund

  • Syk-Dependent Cytokine Induction by Dectin-1 Reveals a Novel Pattern Recognition Pathway for C Type Lectins

    Neil C. Rogers;Emma Wetter Slack;Alexander D. Edwards;Martijn A. Nolte

  • Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

    Santiago Zelenay;Annemarthe G. van der Veen;Jan P. Böttcher;Kathryn J. Snelgrove

  • In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas.

    Caetano Reis e Sousa;Sara Hieny;Tanya Scharton-Kersten;Dragana Jankovic

  • Cytosolic Sensing of Viruses

    Delphine Goubau;Safia Deddouche;Caetano Reis e Sousa

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

    David Sancho;Olivier P Joffre;Anna M. Keller;Neil C. Rogers

  • GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c(+)MHCII(+) Macrophages and Dendritic Cells.

    Julie Helft;Jan Böttcher;Probir Chakravarty;Santiago Zelenay

  • Innate Recognition of Viruses

    Andreas Pichlmair;Caetano Reis e Sousa

  • Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4 + T cell populations lacking helper function

    Roman Spörri;Caetano Reis e Sousa

  • Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.

    Lionel Franz Poulin;Mariolina Salio;Emmanuel Griessinger;Fernando Anjos-Afonso

  • Viral infection switches non-plasmacytoid dendritic cells into high interferon producers

    Sandra S Diebold;Maria Montoya;Hermann Unger;Lena Alexopoulou

  • Inflammatory signals in dendritic cell activation and the induction of adaptive immunity.

    Olivier Joffre;Martijn A. Nolte;Roman Spörri;Caetano Reis e Sousa

  • RIG-I detects viral genomic RNA during negative-strand RNA virus infection.

    Jan Rehwinkel;Choon Ping Tan;Choon Ping Tan;Delphine Goubau;Oliver Schulz

  • CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal.

    Oliver Schulz;Alexander D Edwards;Marco Schito;Julio Aliberti

Frequent Co-Authors

David Sancho
David Sancho Spanish National Centre for Cardiovascular Research
Salomé LeibundGut-Landmann
Salomé LeibundGut-Landmann University of Zurich
Alan Sher
Alan Sher National Institute of Allergy and Infectious Diseases
Ronald N. Germain
Ronald N. Germain National Institute of Allergy and Infectious Diseases
Gordon D. Brown
Gordon D. Brown University of Exeter
Shizuo Akira
Shizuo Akira Osaka University
Charles Swanton
Charles Swanton The Francis Crick Institute
Victor L. J. Tybulewicz
Victor L. J. Tybulewicz The Francis Crick Institute
Julio Aliberti
Julio Aliberti National Institute of Allergy and Infectious Diseases
Sara Hieny
Sara Hieny National Institute of Allergy and Infectious Diseases

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