D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 40 Citations 4,735 108 World Ranking 16642 National Ranking 456

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His main research concerns Biochemistry, Alpha-synuclein, Cell biology, Dopamine and Fibril. His Biochemistry study frequently intersects with other fields, such as Amyloid. His Alpha-synuclein study incorporates themes from Neurodegeneration, Oligomer, Fatty acid, Intracellular and Conformational isomerism.

The study incorporates disciplines such as Inflammation, Microglia and Synaptic vesicle in addition to Cell biology. His research investigates the connection between Microglia and topics such as Neurology that intersect with problems in Parkinson's disease. His Dopamine study combines topics in areas such as Melanin, Tyrosinase and α synuclein.

His most cited work include:

  • Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies (275 citations)
  • Kinetic and Structural Analysis of the Early Oxidation Products of Dopamine ANALYSIS OF THE INTERACTIONS WITH α-SYNUCLEIN (184 citations)
  • Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level (156 citations)

What are the main themes of his work throughout his whole career to date?

Luigi Bubacco spends much of his time researching Biochemistry, Crystallography, Parkinson's disease, Cell biology and Alpha-synuclein. Biochemistry is often connected to Amyloid in his work. His work deals with themes such as Active site, Electron paramagnetic resonance and Copper, which intersect with Crystallography.

Luigi Bubacco works mostly in the field of Parkinson's disease, limiting it down to topics relating to Dopamine and, in certain cases, Oxidative stress. Luigi Bubacco has researched Cell biology in several fields, including Microglia and LRRK2. In his research, Circular dichroism is intimately related to Biophysics, which falls under the overarching field of Alpha-synuclein.

He most often published in these fields:

  • Biochemistry (23.30%)
  • Crystallography (17.48%)
  • Parkinson's disease (17.48%)

What were the highlights of his more recent work (between 2017-2021)?

  • Parkinson's disease (17.48%)
  • Cell biology (16.02%)
  • Dopamine (13.59%)

In recent papers he was focusing on the following fields of study:

Parkinson's disease, Cell biology, Dopamine, Oxidative stress and Biophysics are his primary areas of study. A large part of his Parkinson's disease studies is devoted to Alpha-synuclein. He interconnects Neuroinflammation, Microglia, PINK1 and LRRK2 in the investigation of issues within Cell biology.

His study in the field of Substantia nigra and Dopaminergic also crosses realms of Proximity ligation assay. His work on Fibril as part of general Biophysics research is frequently linked to Tau protein, thereby connecting diverse disciplines of science. His studies in Neurodegeneration integrate themes in fields like Reactivity and Autoxidation, Biochemistry.

Between 2017 and 2021, his most popular works were:

  • USP14 inhibition corrects an in vivo model of impaired mitophagy (32 citations)
  • Impaired dopamine metabolism in Parkinson's disease pathogenesis. (31 citations)
  • Diabetes Mellitus as a Risk Factor for Parkinson's Disease: a Molecular Point of View. (31 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Luigi Bubacco mostly deals with Parkinson's disease, Dopamine, Cell biology, Oxidative stress and Disease. Specifically, his work in Parkinson's disease is concerned with the study of Alpha-synuclein. Many of his research projects under Dopamine are closely connected to Proximity ligation assay with Proximity ligation assay, tying the diverse disciplines of science together.

His biological study spans a wide range of topics, including Parkin, Neuroinflammation, Microglia and LRRK2. Luigi Bubacco works mostly in the field of Oxidative stress, limiting it down to concerns involving Neuroscience and, occasionally, SOD1, Copper deficiency, Homeostasis and Copper. In the subject of general Disease, his work in Neuropathology is often linked to Hyposmia, thereby combining diverse domains of study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Triggering of Inflammasome by Aggregated α–Synuclein, an Inflammatory Response in Synucleinopathies

Gaia Codolo;Nicoletta Plotegher;Tommaso Pozzobon;Marco Brucale.
PLOS ONE (2013)

390 Citations

Kinetic and Structural Analysis of the Early Oxidation Products of Dopamine ANALYSIS OF THE INTERACTIONS WITH α-SYNUCLEIN

Marco Bisaglia;Stefano Mammi;Luigi Bubacco.
Journal of Biological Chemistry (2007)

253 Citations

Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

Massimo Sandal;Francesco Valle;Isabella Tessari;Stefano Mammi.
PLOS Biology (2008)

207 Citations

Structural insights on physiological functions and pathological effects of α-synuclein

Marco Bisaglia;Stefano Mammi;Luigi Bubacco.
The FASEB Journal (2009)

186 Citations

LRRK2 and neuroinflammation: partners in crime in Parkinson's disease?

Isabella Russo;Luigi Bubacco;Elisa Greggio.
Journal of Neuroinflammation (2014)

157 Citations

A Topological Model of the Interaction between α-Synuclein and Sodium Dodecyl Sulfate Micelles†

Marco Bisaglia;Isabella Tessari;Luca Pinato;Massimo Bellanda.
Biochemistry (2005)

134 Citations

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate.

Elisa Belluzzi;Adriano Gonnelli;Maria-Daniela Cirnaru;Antonella Marte.
Molecular Neurodegeneration (2016)

124 Citations

GTPase Activity Regulates Kinase Activity and Cellular Phenotypes of Parkinson's Disease-Associated LRRK2

Alice Biosa;Alzbeta Trancikova;Laura Civiero;Liliane Glauser.
Human Molecular Genetics (2013)

120 Citations

Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease.

Elisa Greggio;Elisabetta Bergantino;Donald Carter;Rili Ahmad.
Journal of Neurochemistry (2005)

108 Citations

The Reaction of α-Synuclein with Tyrosinase: POSSIBLE IMPLICATIONS FOR PARKINSON DISEASE*

Isabella Tessari;Marco Bisaglia;Francesco Valle;Bruno Samorì.
Journal of Biological Chemistry (2008)

107 Citations

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