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Marie-Christine Chartier-Harlin

Marie-Christine Chartier-Harlin

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
20624
World Ranking
13539
National Ranking
514

Overview

Marie-Christine Chartier-Harlin is affiliated with the University of Lille in France and has a research portfolio primarily focused on neurological diseases, particularly Parkinson's disease. Their work spans multiple intersecting fields including Medicine, Biochemistry, Genetics and Molecular Biology, with significant contributions to Neurology and Molecular Biology.

Their research encompasses the following main topics:

  • Parkinson's Disease Mechanisms and Treatments
  • Cellular transport and secretion
  • Lysosomal Storage Disorders Research
  • Neurological diseases and metabolism
  • Alzheimer's disease research and treatments
  • Fungal and yeast genetics research
  • Genetic Neurodegenerative Diseases

Key recent publications by Marie-Christine Chartier-Harlin include:

  • "Glycosphingolipids and neuroinflammation in Parkinson's disease" (2020), published in Molecular Neurodegeneration
  • "Transcriptomic signatures of brain regional vulnerability to Parkinson's disease" (2020), published in Communications Biology
  • "LRRK2 Phosphorylation, More Than an Epiphenomenon" (2020), published in Frontiers in Neuroscience
  • "Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease" (2022), published in Neurology
  • "Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease" (2021), published in Journal of Parkinson's Disease

The scientist frequently collaborates with notable coauthors, including:

  • Jean-Marc Taymans (18 joint publications)
  • Eugénie Mutez (14 joint publications)
  • Ekaterina Rogaeva (7 joint publications)
  • Pau Pástor (7 joint publications)
  • Ashwin Ashok Kumar Sreelatha (6 joint publications)

Marie-Christine Chartier-Harlin's work appears regularly in several scientific journals and publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory) with 5 publications
  • Cells with 4 publications
  • Movement Disorders with 3 publications
  • Frontiers in Neuroscience with 2 publications
  • Neurology with 2 publications

Their research integrates subfields including Neurology, Molecular Biology, Cell Biology, Physiology, and Cellular and Molecular Neuroscience. This multidisciplinary approach supports investigations into cellular transport systems, neuroinflammatory pathways, and genetic underpinnings of neurodegenerative diseases.

Best Publications

  • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.

    Alison Goate;Marie-Christine Chartier-Harlin;Mike Mullan;Jeremy Brown

  • α-synuclein locus duplication as a cause of familial Parkinson's disease

    Marie-Christine Chartier-Harlin;Jennifer M. Kachergus;Christophe Roumier;Vincent Mouroux

  • Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

    Marie Christine Chartier-Harlin;Fiona Crawford;Henry Houlden;Andrew Warren

  • Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.

    Demetrius M. Maraganore;Mariza De Andrade;Alexis Elbaz;Matthew J. Farrer

  • Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

    Chartier-Harlin Mc;Parfitt M;Parfitt M;Legrain S;Pérez-Tur J

  • A full genome scan for late onset Alzheimer's disease

    Patrick Kehoe;Fabienne Wavrant-De Vrieze;Richard Crook;William S. Wu

  • Translation initiator EIF4G1 mutations in familial Parkinson disease

    Marie Christine Chartier-Harlin;Marie Christine Chartier-Harlin;Justus C. Dachsel;Carles Vilariño-Güell;Sarah J. Lincoln

  • Genomic investigation of alpha-synuclein multiplication and parkinsonism

    Owen A. Ross;Adam T. Braithwaite;Lisa M. Skipper;Jennifer Kachergus

  • Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

    Owen A. Ross;Alexandra I. Soto-Ortolaza;Michael G. Heckman;Jan O. Aasly

  • UCHL1 is a Parkinson's disease susceptibility gene

    Demetrius M. Maraganore;Timothy G. Lesnick;Alexis Elbaz;Marie Christine Chartier-Harlin

  • A New Polymorphism in the Apoe Promoter Associated with Risk of Developing Alzheimer's Disease

    Jean-Charles Lambert;Florence Pasquier;Dominique Cottel;Bernard Frigard

  • CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease.

    Alexis Elbaz;Clotilde Levecque;Jacqueline Clavel;Jean-Sébastien Vidal

  • Therapeutic potential of autophagy-enhancing agents in Parkinson's disease

    Tim E. Moors;Jeroen J M Hoozemans;Angela Ingrassia;Tommaso Beccari

  • Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations—the ECTIM Study

    Jean-Charles Lambert;Thierry Brousseau;Véronique Defosse;Alun Evans

  • Pronounced Impact of Th1/E47Cs Mutation Compared With −491 at Mutation on Neural APOE Gene Expression and Risk of Developing Alzheimer's Disease

    Jean-Charles Lambert;Claudine Berr;Florence Pasquier;André Delacourte

  • Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex

    H Bickeböller;D Campion;A Brice;P Amouyel

  • A novel presenilin-2 splice variant in human Alzheimer's disease brain tissue.

    Naoya Sato;Osamu Hori;Atsushi Yamaguchi;Jean‐Charles Lambert

  • Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case–control study

    Clotilde Levecque;Alexis Elbaz;Jacqueline Clavel;Florence Richard

  • Contribution of APOE promoter polymorphisms to Alzheimer's disease risk.

    J. C. Lambert;L. Araria-Goumidi;L. Myllykangas;C. Ellis

  • NADPH oxidases in Parkinson’s disease: a systematic review

    Karim Belarbi;Elodie Cuvelier;Alain Destée;Bernard Gressier

Frequent Co-Authors

Alain Destée
Alain Destée University of Lille
John Hardy
John Hardy University College London
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Matthew J. Farrer
Matthew J. Farrer University of Florida
Jordi Pérez-Tur
Jordi Pérez-Tur Spanish National Research Council
Alexis Elbaz
Alexis Elbaz Versailles Saint-Quentin-en-Yvelines University
Michael Mullan
Michael Mullan Roskamp Institute
André Delacourte
André Delacourte University of Lille
John P. A. Ioannidis
John P. A. Ioannidis Stanford University

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