What is he best known for?
The fields of study he is best known for:
Andrew B. West mostly deals with Molecular biology, LRRK2, Genetics, Parkin and Parkinson's disease.
In his study, Point mutation, Gene expression and Ubiquitin ligase is inextricably linked to Neurodegeneration, which falls within the broad field of Molecular biology.
The study incorporates disciplines such as Microglia, Leucine-rich repeat, Kinase activity and ASK1 in addition to LRRK2.
His Kinase activity research is multidisciplinary, relying on both Cyclin-dependent kinase 4, MAP3K7, Cyclin-dependent kinase 9 and Cyclin-dependent kinase 2.
His Parkin research includes elements of Ubiquitin, Pathogenesis, Mutation, Age of onset and Degenerative disease.
His studies in Parkinson's disease integrate themes in fields like Neuroscience, Mitochondrion and Proteasome.
His most cited work include:
- MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE (971 citations)
- Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity (930 citations)
- A genome-wide linkage and association scan reveals novel loci for autism (492 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in LRRK2, Disease, Kinase, Parkinson's disease and Neurodegeneration.
His LRRK2 study incorporates themes from Molecular biology, Cell biology, Neuroprotection and Kinase activity.
His Disease research is multidisciplinary, incorporating perspectives in Biomarker, Genetics, Gene and Bioinformatics.
His Kinase research is multidisciplinary, incorporating elements of Cancer research, GTPase, Pharmacology and Phosphorylation.
A large part of his Parkinson's disease studies is devoted to Parkin.
His biological study spans a wide range of topics, including Substantia nigra, Neuroinflammation, Neuroscience and Innate immune system.
He most often published in these fields:
- LRRK2 (44.53%)
- Disease (27.34%)
- Kinase (27.34%)
What were the highlights of his more recent work (between 2018-2021)?
- LRRK2 (44.53%)
- Cell biology (21.09%)
- Disease (27.34%)
In recent papers he was focusing on the following fields of study:
Andrew B. West mainly investigates LRRK2, Cell biology, Disease, Neurodegeneration and Kinase.
His LRRK2 research includes elements of Missense mutation, Movement disorders, Montreal Cognitive Assessment and Kinase activity.
His Cell biology study also includes fields such as
- Substantia nigra together with Neuroprotection,
- Parkin that intertwine with fields like Oxidative stress and Human brain.
He is involved in the study of Disease that focuses on Parkinson's disease in particular.
Andrew B. West interconnects Dementia with Lewy bodies, Dementia and Dopaminergic in the investigation of issues within Neurodegeneration.
His Kinase research is multidisciplinary, incorporating elements of Pharmacology and Phosphorylation.
Between 2018 and 2021, his most popular works were:
- Parkinson disease and the immune system - associations, mechanisms and therapeutics. (41 citations)
- Proteomic analysis of urinary extracellular vesicles reveal biomarkers for neurologic disease. (26 citations)
- The unlikely partnership between LRRK2 and α-synuclein in Parkinson's disease. (16 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in LRRK2, Neurodegeneration, Disease, Cell biology and Exosome.
His study on LRRK2 is mostly dedicated to connecting different topics, such as Kinase.
The various areas that he examines in his Kinase study include GTPase, Mutation, Substantia nigra, Dopaminergic and Neuroprotection.
The concepts of his Disease study are interwoven with issues in Biomarker, Neuroscience and Bioinformatics.
Endosome is the focus of his Cell biology research.
His studies in Parkinson's disease integrate themes in fields like Neuroinflammation, Mitochondrion and Kinase activity.
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