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Chemistry

D-Index
48
Citations
7508
World Ranking
15327
National Ranking
1203

Overview

Shun Hirota is affiliated with the Nara Institute of Science and Technology in Japan and primarily works within the field of Biochemistry, Genetics and Molecular Biology. Their research output comprises 38 publications mainly focusing on molecular biology, materials chemistry, renewable energy, sustainability and the environment, cell biology, and radiology, nuclear medicine and imaging.

The scientist's research addresses topics such as glycosylation and glycoproteins research, hemoglobin structure and function, monoclonal and polyclonal antibodies research, enzyme structure and function, crystallization and solubility studies, X-ray diffraction in crystallography, and metalloenzymes and iron-sulfur proteins.

Shun Hirota has co-authored frequently with several researchers, including Tsuyoshi Mashima, Masaru Yamanaka, Yasuteru Shigeta, Catur Jatmika, and Kazumo Wakabayashi. Their frequent publication venues include The Cambridge Structural Database, Chemical Communications, The Journal of Physical Chemistry B, Chemistry Letters, and Chemistry - A European Journal.

Recent papers by Shun Hirota demonstrate focus on metalloproteins and cytochrome studies, including:

  • Use of 3D domain swapping in constructing supramolecular metalloproteins, 2021, Chemical Communications
  • New Aspects of Cytochrome c: 3D Domain Swapping, Membrane Interaction, Peroxidase Activity, and Met80 Sulfoxide Modification, 2020, Bulletin of the Chemical Society of Japan

Other recent publications not authored by Hirota but closely connected in the field cover coordination spheres in enzymes and catalytic mechanisms and are published in venues such as Chemical Reviews, Accounts of Chemical Research, and ChemBioChem.

Best Publications

  • Activation process of [NiFe] hydrogenase elucidated by high-resolution X-Ray analyses: conversion of the ready to the unready state

    Hideaki Ogata;Shun Hirota;Shun Hirota;Asuka Nakahara;Hirofumi Komori

  • Structural studies of the carbon monoxide complex of [NiFe]hydrogenase from Desulfovibrio vulgaris Miyazaki F: suggestion for the initial activation site for dihydrogen.

    Hideaki Ogata;Yasutaka Mizoguchi;Nobuhiro Mizuno;Kunio Miki

  • Cytochrome c polymerization by successive domain swapping at the C-terminal helix

    Shun Hirota;Yoko Hattori;Satoshi Nagao;Midori Taketa

  • Crystal Structure and Reversible O2-Binding of a Room Temperature Stable μ-η2:η2-Peroxodicopper(II) Complex of a Sterically Hindered Hexapyridine Dinucleating Ligand

    Masahito Kodera;Kou Katayama;Yoshimitsu Tachi;Koji Kano

  • Time-resolved resonance Raman elucidation of the pathway for dioxygen reduction by cytochrome c oxidase

    Takashi Ogura;Satoshi Takahashi;Shun Hirota;Kyoko Shinzawa-Itoh

  • click peptide based on the O-acyl isopeptide method : Control of Aβ1 42 production from a photo-triggered Aβ1 42 analogue

    Atsuhiko Taniguchi;Youhei Sohma;Maiko Kimura;Takuma Okada

  • Role of copper ion in bacterial copper amine oxidase: spectroscopic and crystallographic studies of metal-substituted enzymes.

    Sei'ichiro Kishishita;Toshihide Okajima;Misa Kim;Hiroshi Yamaguchi

  • Time-Resolved Resonance Raman Evidence for Tight Coupling between Electron Transfer and Proton Pumping of Cytochrome c Oxidase upon the Change from the FeV Oxidation Level to the FeIV Oxidation Level

    Takashi Ogura;Shun Hirota;Denis A. Proshlyakov;Kyoko Shinzawa-Itoh

  • Hydroperoxo--copper(II) complex stabilized by N(S)s-type ligand having a phenyl thioether.

    Masahito Kodera;Toshio Kita;Izumi Miura;Noritoshi Nakayama

  • Ligand binding properties of myoglobin reconstituted with iron porphycene: unusual O2 binding selectivity against CO binding.

    Takashi Matsuo;Hirohisa Dejima;Shun Hirota;Dai Murata

  • Dioxygen binding to a simple myoglobin model in aqueous solution.

    Koji Kano;Hiroaki Kitagishi;Masahito Kodera;Shun Hirota

  • A new class of rhodamine luminophores: design, syntheses and aggregation-induced emission enhancement.

    Shinichiro Kamino;Yuka Horio;Seiji Komeda;Katsuhiko Minoura

  • Peroxidase activity enhancement of horse cytochrome c by dimerization

    Zhonghua Wang;Zhonghua Wang;Takashi Matsuo;Satoshi Nagao;Shun Hirota

  • Four-electron reduction of dioxygen by a multicopper oxidase, CueO, and roles of Asp112 and Glu506 located adjacent to the trinuclear copper center.

    Kunishige Kataoka;Ryosuke Sugiyama;Shun Hirota;Megumi Inoue

  • Thermodynamics of apoplastocyanin folding: comparison between experimental and theoretical results.

    Takashi Yoshidome;Masahiro Kinoshita;Shun Hirota;Shun Hirota;Naoki Baden

  • Iron Porphyrin−Cyclodextrin Supramolecular Complex as a Functional Model of Myoglobin in Aqueous Solution

    Koji Kano;Hiroaki Kitagishi;Camille Dagallier;Masahito Kodera

  • Development of first photoresponsive prodrug of paclitaxel.

    Mariusz Skwarczynski;Mayo Noguchi;Shun Hirota;Shun Hirota;Youhei Sohma

  • Resonance Raman Investigation of Fe−N−O Structure of Nitrosylheme in Myoglobin and Its Mutants

    Takeshi Tomita;Shun Hirota;Takashi Ogura;John S. Olson

  • Efficient Oxidative Cycloreversion Reaction of Photochromic Dithiazolythiazole

    Takuya Nakashima;Yoshiyuki Kajiki;Sayo Fukumoto;Maki Taguchi

  • Synthesis, Structure, and Greatly Improved Reversible O2 Binding in a Structurally Modulated μ-η2:η2-Peroxodicopper(II) Complex with Room-Temperature Stability†

    Masahito Kodera;Yuuji Kajita;Yoshimitsu Tachi;Kou Katayama

  • Perturbation of the Fe−O2 Bond by Nearby Residues in Heme Pocket: Observation of νFe-O2 Raman Bands for Oxymyoglobin Mutants

    Shun Hirota;Tiansheng Li;George N. Phillips;John S. Olson

  • Creation of an artificial metalloprotein with a Hoveyda–Grubbs catalyst moiety through the intrinsic inhibition mechanism of α-chymotrypsin

    Takashi Matsuo;Chie Imai;Takefumi Yoshida;Takashi Saito

Frequent Co-Authors

Takashi Ogura
Takashi Ogura University of Hyogo
Koji Kano
Koji Kano Doshisha University
Mikio Kataoka
Mikio Kataoka Nara Institute of Science and Technology
Shun'ichi Kuroda
Shun'ichi Kuroda Osaka University
Yoshihito Watanabe
Yoshihito Watanabe Nagoya University
Takashi Hayashi
Takashi Hayashi Osaka University
Teizo Kitagawa
Teizo Kitagawa University of Hyogo
Shinya Yoshikawa
Shinya Yoshikawa University of Hyogo
Masahide Terazima
Masahide Terazima Kyoto University
Yoshiaki Kiso
Yoshiaki Kiso Nagahama Institute of Bio-Science and Technology

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