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Immunology

D-Index
69
Citations
15076
World Ranking
2523
National Ranking
99

Research.com Recognitions

  • 2016 - Fellow of the Australian Academy of Health and Medical Science

Overview

Ian P. Wicks is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research spans across multiple intersecting fields, including Medicine, Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. The scientist's work further delves into specific subfields such as Immunology, Molecular Biology, Epidemiology, Surgery, and Pulmonary and Respiratory Medicine.

Their research addresses various topics, prominently focusing on immune system function and related pathological mechanisms. The main themes in their work include:

  • Immune Response and Inflammation
  • Inflammatory Myopathies and Dermatomyositis
  • Inflammasome and Immune Disorders
  • Cell Death Mechanisms and Regulation
  • Interferon and Immune Responses
  • Immune Cell Function and Interaction
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Ian P. Wicks has contributed to a range of publication venues, with frequent outputs appearing in:

  • Clinical & Translational Immunology
  • Annals of the Rheumatic Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Immunology

Selected recent papers authored or co-authored by Ian P. Wicks include:

  • TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells, 2020, Cell Reports
  • Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma, 2021, Nature Immunology
  • Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease, 2020, Nature Reviews Rheumatology
  • G-CSF - A double edge sword in neutrophil mediated immunity, 2021, Seminars in Immunology
  • Efficacy and safety of mavrilimumab in giant cell arteritis: a phase 2, randomised, double-blind, placebo-controlled trial, 2022, Annals of the Rheumatic Diseases

The scientist has collaborated with a number of frequent co-authors, including:

  • Cynthia Louis
  • Jessica Day
  • Damian B. D'Silva
  • Katherine Martin
  • Jacinta Hansen

Ian P. Wicks was recognized as a Fellow of the Australian Academy of Health and Medical Science in 2016.

Best Publications

  • Accelerated atherosclerosis: An extraarticular feature of rheumatoid arthritis?

    S. Van Doornum;G. McColl;I. P. Wicks

  • Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

    Shalin H Naik;Shalin H Naik;Donald Metcalf;Annemarie van Nieuwenhuijze;Ian Wicks

  • RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

    Kate E. Lawlor;Nufail Khan;Alison Mildenhall;Motti Gerlic

  • TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.

    Katherine R. Balka;Katherine R. Balka;Katherine R. Balka;Cynthia Louis;Cynthia Louis;Tahnee L. Saunders;Amber M. Smith

  • The role of the LFA-1/ICAM-1 interaction in human leukocyte homing and adhesion

    S. O. Wawryk;J. R. Novotny;I. P. Wicks;David Wilkinson

  • Interleukin-6 modulates production of T lymphocyte-derived cytokines in antigen-induced arthritis and drives inflammation-induced osteoclastogenesis.

    Peter K K Wong;Julian M W Quinn;Natalie A Sims;Annemarie van Nieuwenhuijze

  • Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis.

    Ian K. Campbell;John A. Hamilton;Ian P. Wicks

  • Targeting GM-CSF in inflammatory diseases.

    Ian P. Wicks;Andrew W. Roberts

  • Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation.

    Matthias Ernst;Melissa Inglese;Paul Waring;Ian K. Campbell

  • Reduced arterial elasticity in rheumatoid arthritis and the relationship to vascular disease risk factors and inflammation.

    Melinda Wong;Ling Toh;Andrew Wilson;Kevin Rowley

  • SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1–dependent inflammatory arthritis

    Peter K.K. Wong;Paul J. Egan;Ben A. Croker;Kristy O’Donnell

  • Granulocyte colony-stimulating factor and neutrophils--forgotten mediators of inflammatory disease.

    Jo L Eyles;Andrew W Roberts;Donald Metcalf;Ian P Wicks

  • Infection Mobilizes Hematopoietic Stem Cells through Cooperative NOD-like Receptor and Toll-like Receptor Signaling

    Aaron Burberry;Melody Y. Zeng;Lei Ding;Ian Wicks

  • Distinct roles for the NF-κB1 (p50) and c-Rel transcription factors in inflammatory arthritis

    Ian K. Campbell;Steve Gerondakis;Kristy O’Donnell;Ian P. Wicks

  • G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis.

    Ann L. Cornish;Ian K. Campbell;Brent S. McKenzie;Simon Chatfield

  • Screening for atherosclerosis in patients with rheumatoid arthritis: Comparison of two in vivo tests of vascular function

    S. Van Doornum;G. Mccoll;A. Jenkins;Daniel Green

  • Atorvastatin reduces arterial stiffness in patients with rheumatoid arthritis

    S Van Doornum;G McColl;I P Wicks

  • A pilot randomized trial comparing CD34-selected versus unmanipulated hemopoietic stem cell transplantation for severe, refractory rheumatoid arthritis.

    John Moore;Peter Brooks;Sam Milliken;Jim Biggs

  • Expression of receptor tyrosine kinase Axl and its ligand Gas6 in rheumatoid arthritis: evidence for a novel endothelial cell survival pathway.

    Kristy O'Donnell;Inge Clara Harkes;Loretta Dougherty;Ian Peter Wicks

  • Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines.

    I P Wicks;D Wilkinson;E Salvaris;A W Boyd

Frequent Co-Authors

Kate E. Lawlor
Kate E. Lawlor Hudson Institute of Medical Research
Seth L. Masters
Seth L. Masters Hudson Institute of Medical Research
Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Richard H. Osborne
Richard H. Osborne Swinburne University of Technology
Andrew W. Roberts
Andrew W. Roberts Walter and Eliza Hall Institute of Medical Research
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Andrew W. Boyd
Andrew W. Boyd University of Queensland
Richard J. Simpson
Richard J. Simpson La Trobe University
Yifan Zhan
Yifan Zhan Walter and Eliza Hall Institute of Medical Research

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