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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
11718
World Ranking
16559
National Ranking
6853

Overview

Hsiou-Chi Liou is affiliated with Cornell University in the United States and conducts research primarily in the fields of biochemistry, genetics, and molecular biology. Their work also spans immunology, microbiology, and medicine. The scientist's research encompasses several subfields including molecular biology, immunology, organic chemistry, hematology, and cancer research.

The main research topics addressed by Hsiou-Chi Liou involve RNA interference and gene delivery, immunotherapy and immune responses, multiple myeloma research and treatments, NF-κB signaling pathways, quinazolinone synthesis and applications, synthesis and biological activity, and chemokine receptors and signaling.

The researcher has contributed papers to a variety of academic journals, notably:

  • Targeted Lymphoma Therapy Using a Gold Nanoframework-Based Drug Delivery System (2023, ACS Applied Materials & Interfaces)
  • Inhibition of NF-κB DNA Binding Suppresses Myeloma Growth via Intracellular Redox and Tumor Microenvironment Modulation (2022, Molecular Cancer Therapeutics)
  • Targeted Nanotherapy of Hematologic Malignancies Using Gold Nanoframework-Based Delivery of a Novel NF-Kb Inhibitor (2022, Blood)

Frequent collaborators include Manpreet Bariana, Elena Cassella, Samedy Ouk, Johannes L. Zakrzewski, and Beilu Zhang, with multiple co-authored works contributing to their scientific output.

Publication venues where their work appears most often include ACS Applied Materials & Interfaces, Molecular Cancer Therapeutics, and Blood.

Best Publications

  • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses

    William C Sha;Hsiou-Chi Liou;Elaine I Tuomanen;David Baltimore

  • Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

    Hsiou-Chi Liou;David Baltimore

  • DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

    Garry P. Nolan;Sankar Ghosh;Hsiou-Chi Liou;Paul Tempst

  • The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

    T. Fujita;G. P. Nolan;Hsiou-Chi Liou;M. L. Scott

  • The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms.

    M. L. Scott;T. Fujita;Hsiou-Chi Liou;G. P. Nolan

  • Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

    Qingguo Ruan;Vasumathi Kameswaran;Yukiko Tone;Li Li

  • Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation

    Hsiou-Chi Liou;William C. Sha;Martin L. Scott;David Baltimore

  • A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter

    Hsiou-Chi Liou;Mark R. Boothby;Patricia W. Finn;Ruth Davidon

  • Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages.

    Shomyseh Sanjabi;Alexander Hoffmann;Hsiou-Chi Liou;David Baltimore

  • The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.

    Garry P. Nolan;Takashi Fujita;Kishor Bhatia;Conrad Huppi

  • mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.

    L. B. Ivashkiv;Hsiou-Chi Liou;C. J. Kara;W. W. Lamph

  • The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis

    Qingguo Ruan;Vasumathi Kameswaran;Yan Zhang;Shijun Zheng

  • A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.

    Young Chul Park;Hong Ye;Constance Hsia;Deena Segal

  • Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation

    Brendan A. Hilliard;Nicola Mason;Lingyun Xu;Jing Sun

  • The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50.

    H.C. Liou;G.P. Nolan;S. Ghosh;T. Fujita

  • A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-rel.

    Jonathan M. Levenson;Sangdun Choi;Sun Young Lee;Yun Anna Cao

  • Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event.

    Amy S. Weinmann;Deborah M. Mitchell;Shomyseh Sanjabi;Michelle N. Bradley

  • Essential Roles of c-Rel in TLR-Induced IL-23 p19 Gene Expression in Dendritic Cells

    Ruaidhrí J. Carmody;Qingguo Ruan;Hsiou-Chi Liou;Youhai H. Chen

  • C-REL IS ESSENTIAL FOR B LYMPHOCYTE SURVIVAL AND CELL CYCLE PROGRESSION

    Joseph R. Tumang;Alexander Owyang;Sofija Andjelic;Zhuang Jin

  • NF-κB1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-κB2 p100 to p52 in quiescent mature B cells

    Eunice N. Hatada;Richard K.G. Do;Amos Orlofsky;Hsiou Chi Liou

Frequent Co-Authors

Laurie H. Glimcher
Laurie H. Glimcher Harvard University
David Baltimore
David Baltimore California Institute of Technology
Youhai H. Chen
Youhai H. Chen University of Pennsylvania
Garry P. Nolan
Garry P. Nolan Stanford University
Christopher A. Hunter
Christopher A. Hunter University of Pennsylvania
Mark Boothby
Mark Boothby Vanderbilt University Medical Center
Martin L. Scott
Martin L. Scott Biogen (United States)
Sankar Ghosh
Sankar Ghosh Columbia University
Lionel B. Ivashkiv
Lionel B. Ivashkiv Hospital for Special Surgery
Manikkam Suthanthiran
Manikkam Suthanthiran Cornell University

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