D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 14,336 114 World Ranking 1967 National Ranking 966

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

Youhai H. Chen mainly focuses on Immunology, Immune system, Experimental autoimmune encephalomyelitis, Inflammation and Cell biology. His work on Apoptosis expands to the thematically related Immunology. His Immune system research includes elements of Cancer research and Cytokine.

Youhai H. Chen has researched Experimental autoimmune encephalomyelitis in several fields, including Myelin, Myelin basic protein, Interleukin 10 and T cell. His work in Inflammation addresses subjects such as Cellular differentiation, which are connected to disciplines such as NFAT, CREB, SMAD, FOXP3 and NFATC Transcription Factors. Youhai H. Chen works mostly in the field of Cell biology, limiting it down to concerns involving Receptor and, occasionally, Immunity.

His most cited work include:

  • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis (1838 citations)
  • Peripheral deletion of antigen-reactive T cells in oral tolerance. (732 citations)
  • Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21 (730 citations)

What are the main themes of his work throughout his whole career to date?

Youhai H. Chen mostly deals with Immunology, Cell biology, Cancer research, Apoptosis and Tumor necrosis factor alpha. His Immunology research focuses on Experimental autoimmune encephalomyelitis, Inflammation, Immune system, T cell and Antigen. His studies deal with areas such as Encephalomyelitis, Myelin, Myelin basic protein and Autoimmune disease as well as Experimental autoimmune encephalomyelitis.

His research in Cell biology tackles topics such as Transcription factor which are related to areas like NF-κB. His Cancer research research includes themes of Cell, Cell growth, Carcinogenesis, Downregulation and upregulation and Programmed cell death. The Apoptosis study combines topics in areas such as Molecular biology, Cell culture, HBx and Arthritis.

He most often published in these fields:

  • Immunology (37.86%)
  • Cell biology (31.55%)
  • Cancer research (21.36%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cell biology (31.55%)
  • Cancer research (21.36%)
  • Inflammation (16.50%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cell biology, Cancer research, Inflammation, Tumor necrosis factor alpha and Immunology. His biological study spans a wide range of topics, including Regulator and Autophagy. His Cancer research research integrates issues from Carcinogenesis, Cancer immunotherapy, Cell growth and REL.

His work on Leukocyte migration and CXCL1 as part of general Inflammation study is frequently linked to Intervertebral disc and ADAM8, bridging the gap between disciplines. His work deals with themes such as Apoptosis, Programmed cell death, Signal transduction, Proinflammatory cytokine and Kinase, which intersect with Tumor necrosis factor alpha. His Immune system study deals with Interleukin 12 intersecting with Innate lymphoid cell.

Between 2014 and 2021, his most popular works were:

  • Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response (670 citations)
  • COVID-19: immunopathogenesis and Immunotherapeutics. (75 citations)
  • TIPE1 induces apoptosis by negatively regulating Rac1 activation in hepatocellular carcinoma cells. (40 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

His primary scientific interests are in Cell biology, Cancer research, Immunology, Inflammation and Immune system. His work in Cell biology addresses issues such as Tumor necrosis factor alpha, which are connected to fields such as Apoptosis, Signal transduction, RAC1 and Kinase. His Cancer research study combines topics from a wide range of disciplines, such as Cell growth, Myeloid-derived Suppressor Cell, Proinflammatory cytokine, Tumor progression and Lipid metabolism.

His Disease research extends to the thematically linked field of Immunology. The study incorporates disciplines such as GTPase, Cytoskeleton, Second messenger system, Encephalomyelitis and Programmed cell death in addition to Inflammation. His Immune system research is multidisciplinary, relying on both Microvesicles, Antibody and Melanoma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

Youhai Chen;Vijay K. Kuchroo;Jun-Ichi Inobe;David A. Hafler.
Science (1994)

2400 Citations

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

Frederick J Sheedy;Eva Palsson-McDermott;Elizabeth J Hennessy;Cara Martin.
Nature Immunology (2010)

996 Citations

Peripheral deletion of antigen-reactive T cells in oral tolerance.

Youhai Chen;Jun-ichi Inobe;Reinhard Marks;Patricia Gonnella.
Nature (1995)

912 Citations

IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells

Elena B. Samoilova;Jennifer L. Horton;Brendan Hilliard;Tzu-Shang T. Liu.
Journal of Immunology (1998)

506 Citations

Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Is an Inhibitor of Autoimmune Inflammation and Cell Cycle Progression

Kaimei Song;Yiguang Chen;Rüdiger Göke;Andreas Wilmen.
Journal of Experimental Medicine (2000)

459 Citations

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Gang Chen;Alexander C. Huang;Wei Zhang;Wei Zhang;Gao Zhang.
Nature (2018)

456 Citations

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL −/− mice

Salah-Eddine Lamhamedi-Cherradi;Shi-Jun Zheng;Kimberly A Maguschak;Jacques Peschon.
Nature Immunology (2003)

430 Citations

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

Qingguo Ruan;Vasumathi Kameswaran;Yukiko Tone;Li Li.
Immunity (2009)

386 Citations

TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis

Honghong Sun;Shunyou Gong;Ruaidhri J. Carmody;Anja Hilliard.
Cell (2008)

355 Citations

IL‐4 is a differentiation factor for transforming growth factor‐β secreting Th3 cells and oral administration of IL‐4 enhances oral tolerance in experimental allergic encephalomyelitis

Jun-ichi Inobe;Anthony J. Slavin;Yoshinori Komagata;Youhai Chen.
European Journal of Immunology (1998)

328 Citations

Best Scientists Citing Youhai H. Chen

Howard L. Weiner

Howard L. Weiner

Harvard University

Publications: 103

Vijay K. Kuchroo

Vijay K. Kuchroo

Harvard University

Publications: 40

Cathy H. Wu

Cathy H. Wu

University of Delaware

Publications: 38

Wafik S. El-Deiry

Wafik S. El-Deiry

Brown University

Publications: 37

Cezmi A. Akdis

Cezmi A. Akdis

University of Zurich

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Hideo Yagita

Hideo Yagita

Juntendo University

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Vladimir N. Uversky

Vladimir N. Uversky

University of South Florida

Publications: 30

Abdolmohamad Rostami

Abdolmohamad Rostami

Thomas Jefferson University

Publications: 29

Jiangning Song

Jiangning Song

Monash University

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Lloyd Mayer

Lloyd Mayer

Icahn School of Medicine at Mount Sinai

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Shimon Sakaguchi

Shimon Sakaguchi

Osaka University

Publications: 26

Jens Nielsen

Jens Nielsen

Chalmers University of Technology

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Mübeccel Akdis

Mübeccel Akdis

University of Zurich

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Frauke Zipp

Frauke Zipp

Johannes Gutenberg University of Mainz

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Henning Hermjakob

Henning Hermjakob

European Bioinformatics Institute

Publications: 23

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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