Youhai H. Chen mainly focuses on Immunology, Immune system, Experimental autoimmune encephalomyelitis, Inflammation and Cell biology. His work on Apoptosis expands to the thematically related Immunology. His Immune system research includes elements of Cancer research and Cytokine.
Youhai H. Chen has researched Experimental autoimmune encephalomyelitis in several fields, including Myelin, Myelin basic protein, Interleukin 10 and T cell. His work in Inflammation addresses subjects such as Cellular differentiation, which are connected to disciplines such as NFAT, CREB, SMAD, FOXP3 and NFATC Transcription Factors. Youhai H. Chen works mostly in the field of Cell biology, limiting it down to concerns involving Receptor and, occasionally, Immunity.
Youhai H. Chen mostly deals with Immunology, Cell biology, Cancer research, Apoptosis and Tumor necrosis factor alpha. His Immunology research focuses on Experimental autoimmune encephalomyelitis, Inflammation, Immune system, T cell and Antigen. His studies deal with areas such as Encephalomyelitis, Myelin, Myelin basic protein and Autoimmune disease as well as Experimental autoimmune encephalomyelitis.
His research in Cell biology tackles topics such as Transcription factor which are related to areas like NF-κB. His Cancer research research includes themes of Cell, Cell growth, Carcinogenesis, Downregulation and upregulation and Programmed cell death. The Apoptosis study combines topics in areas such as Molecular biology, Cell culture, HBx and Arthritis.
His scientific interests lie mostly in Cell biology, Cancer research, Inflammation, Tumor necrosis factor alpha and Immunology. His biological study spans a wide range of topics, including Regulator and Autophagy. His Cancer research research integrates issues from Carcinogenesis, Cancer immunotherapy, Cell growth and REL.
His work on Leukocyte migration and CXCL1 as part of general Inflammation study is frequently linked to Intervertebral disc and ADAM8, bridging the gap between disciplines. His work deals with themes such as Apoptosis, Programmed cell death, Signal transduction, Proinflammatory cytokine and Kinase, which intersect with Tumor necrosis factor alpha. His Immune system study deals with Interleukin 12 intersecting with Innate lymphoid cell.
His primary scientific interests are in Cell biology, Cancer research, Immunology, Inflammation and Immune system. His work in Cell biology addresses issues such as Tumor necrosis factor alpha, which are connected to fields such as Apoptosis, Signal transduction, RAC1 and Kinase. His Cancer research study combines topics from a wide range of disciplines, such as Cell growth, Myeloid-derived Suppressor Cell, Proinflammatory cytokine, Tumor progression and Lipid metabolism.
His Disease research extends to the thematically linked field of Immunology. The study incorporates disciplines such as GTPase, Cytoskeleton, Second messenger system, Encephalomyelitis and Programmed cell death in addition to Inflammation. His Immune system research is multidisciplinary, relying on both Microvesicles, Antibody and Melanoma.
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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis
Youhai Chen;Vijay K. Kuchroo;Jun-Ichi Inobe;David A. Hafler.
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
Frederick J Sheedy;Eva Palsson-McDermott;Elizabeth J Hennessy;Cara Martin.
Nature Immunology (2010)
Peripheral deletion of antigen-reactive T cells in oral tolerance.
Youhai Chen;Jun-ichi Inobe;Reinhard Marks;Patricia Gonnella.
IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells
Elena B. Samoilova;Jennifer L. Horton;Brendan Hilliard;Tzu-Shang T. Liu.
Journal of Immunology (1998)
Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Is an Inhibitor of Autoimmune Inflammation and Cell Cycle Progression
Kaimei Song;Yiguang Chen;Rüdiger Göke;Andreas Wilmen.
Journal of Experimental Medicine (2000)
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Gang Chen;Alexander C. Huang;Wei Zhang;Wei Zhang;Gao Zhang.
Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL −/− mice
Salah-Eddine Lamhamedi-Cherradi;Shi-Jun Zheng;Kimberly A Maguschak;Jacques Peschon.
Nature Immunology (2003)
Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome
Qingguo Ruan;Vasumathi Kameswaran;Yukiko Tone;Li Li.
TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis
Honghong Sun;Shunyou Gong;Ruaidhri J. Carmody;Anja Hilliard.
IL‐4 is a differentiation factor for transforming growth factor‐β secreting Th3 cells and oral administration of IL‐4 enhances oral tolerance in experimental allergic encephalomyelitis
Jun-ichi Inobe;Anthony J. Slavin;Yoshinori Komagata;Youhai Chen.
European Journal of Immunology (1998)
Profile was last updated on December 6th, 2021.
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