The scientist’s investigation covers issues in Genetics, Mutation, Cancer research, Cancer and Exome. His Genetics research focuses on Massive parallel sequencing, Genome, DNA sequencing and Human genome. While the research belongs to areas of Mutation, Trevor J. Pugh spends his time largely on the problem of PTEN, intersecting his research to questions surrounding Fusion gene, Gene rearrangement, Prostate and Prostate cancer.
His Cancer research research includes themes of Papillomaviridae, KRAS, Immunology and DNA methylation. His Cancer research includes elements of Chromatin and Human genetics. He combines subjects such as Mutation rate and Adenocarcinoma with his study of Exome.
His primary areas of study are Cancer research, Internal medicine, Oncology, Genetics and Cancer. His Cancer research study combines topics from a wide range of disciplines, such as Mutation, Immune system, Bioinformatics and Somatic cell. His biological study spans a wide range of topics, including Endometrial cancer, Chemotherapy, Lynch syndrome and PMS2.
Exome, Gene, Germline mutation, DNA sequencing and Genome are among the areas of Genetics where Trevor J. Pugh concentrates his study. His Exome research incorporates elements of Mutation rate and Loss of heterozygosity. His research in Genome is mostly focused on Human genome.
Trevor J. Pugh mostly deals with Internal medicine, Oncology, Cancer research, Cancer and Computational biology. His studies deal with areas such as Pembrolizumab, MLH1, Lynch syndrome, PMS2 and Endometrial cancer as well as Oncology. His Cancer research research incorporates themes from Mutation, Cancer cell, Transcription factor and Immune system, Immunotherapy.
His Cancer study incorporates themes from Prospective cohort study, Clinical trial and RNA splicing. The various areas that he examines in his Computational biology study include Pharmacogenomics, Gene, Somatic cell, Peripheral blood and Local sequence. His study with Antigen involves better knowledge in Genetics.
Trevor J. Pugh focuses on Cancer research, Internal medicine, Oncology, Gene and CRISPR. His Cancer research research incorporates elements of Mutation, Cell, Transcription factor and PI3K/AKT/mTOR pathway. His Mutation study frequently draws connections between adjacent fields such as Prostate cancer.
His Internal medicine research is multidisciplinary, incorporating perspectives in Molecular analysis and Methylation. The Oncology study combines topics in areas such as Pembrolizumab, MLH1, Adverse effect, Family history and MSH6. His work carried out in the field of Cancer brings together such families of science as Clinical trial and Microsatellite instability.
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Mutational heterogeneity in cancer and the search for new cancer-associated genes
Michael S. Lawrence;Petar Stojanov;Petar Stojanov;Paz Polak;Paz Polak;Paz Polak;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov.
Comprehensive molecular characterization of urothelial bladder carcinoma
John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang.
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
Marcin Imielinski;Alice H. Berger;Alice H. Berger;Peter S. Hammerman;Peter S. Hammerman;Bryan Hernandez.
Initial genome sequencing and analysis of multiple myeloma
Michael A. Chapman;Michael S. Lawrence;Jonathan J. Keats;Kristian Cibulskis.
The genomic complexity of primary human prostate cancer
Michael F. Berger;Michael F. Berger;Michael S. Lawrence;Francesca Demichelis;Yotam Drier.
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
Sohrab P. Shah;Ryan D. Morin;Jaswinder Khattra;Leah Prentice.
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors
Esra A. Akbay;Esra A. Akbay;Shohei Koyama;Julian Carretero;Abigail Altabef;Abigail Altabef.
Cancer Discovery (2013)
AACR project genie: Powering precision medicine through an international consortium
S. M. Sweeney;E. Cerami;A. Baras;T. J. Pugh.
Cancer Discovery (2017)
The genetic landscape of high-risk neuroblastoma
Trevor J Pugh;Olena Morozova;Edward F Attiyeh;Edward F Attiyeh;Shahab Asgharzadeh;Shahab Asgharzadeh.
Nature Genetics (2013)
DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.
David Roulois;Helen Loo Yau;Helen Loo Yau;Rajat Singhania;Yadong Wang.
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