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Biology and Biochemistry

D-Index
52
Citations
7962
World Ranking
16849
National Ranking
6947

Overview

Robert N. Husson is affiliated with Boston Children's Hospital in the United States. Their research spans multiple disciplines within medicine, biochemistry, genetics, and molecular biology.

The main fields of study for Robert N. Husson include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their research further focuses on several subfields, notably:

  • Infectious Diseases
  • Epidemiology
  • Immunology
  • Molecular Biology
  • Molecular Medicine

Key topics that feature prominently in their work are:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • RNA and protein synthesis mechanisms
  • Immune responses and vaccinations
  • Immunodeficiency and Autoimmune Disorders
  • Antibiotic Resistance in Bacteria
  • Child Nutrition and Water Access

Their recent papers include:

  • Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation (2020), Vaccine
  • BCG as a Case Study for Precision Vaccine Development: Lessons From Vaccine Heterogeneity, Trained Immunity, and Immune Ontogeny (2020), Frontiers in Microbiology
  • Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility (2020), PLoS Pathogens
  • Mycobacterium tuberculosis VapC4 toxin engages small ORFs to initiate an integrated oxidative and copper stress response (2021), Proceedings of the National Academy of Sciences
  • Multi-omic regulatory networks capture downstream effects of kinase inhibition in Mycobacterium tuberculosis (2021), npj Systems Biology and Applications

Frequent co-authors collaborating with Robert N. Husson include:

  • Valdir C. Barth
  • Nancy A. Woychik
  • Asimenia Angelidou
  • Maria Giulia Conti
  • Joann Diray-Arce

Robert N. Husson has published multiple papers in the following venues:

  • Vaccine
  • Frontiers in Microbiology
  • PLoS Pathogens
  • Proceedings of the National Academy of Sciences
  • npj Systems Biology and Applications

Best Publications

  • In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria

    Eric J. Rubin;Brian J. Akerley;Veronica N. Novik;David J. Lampe

  • The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape

    Choong-Min Kang;Derek W. Abbott;Sang Tae Park;Christopher C. Dascher

  • The Alternative Sigma Factor SigH Regulates Major Components of Oxidative and Heat Stress Responses in Mycobacterium tuberculosis

    Sahadevan Raman;Taeksun Song;Xiaoling Puyang;Stoyan Bardarov

  • Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases

    Sladjana Prisic;Selasi Dankwa;Daniel Schwartz;Michael F. Chou

  • Dideoxyinosine in children with symptomatic human immunodeficiency virus infection

    Karina M. Butler;Robert N. Husson;Frank M. Balis;Pim Brouwers

  • Gene replacement and expression of foreign DNA in mycobacteria.

    R N Husson;B E James;R A Young

  • Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria

    Choong-Min Kang;Seeta Nyayapathy;Jung-Yeon Lee;Joo-Won Suh

  • Lymphadenitis Due to Nontuberculous Mycobacteria in Children: Presentation and Response to Therapy

    Rohan Hazra;Caroline D. Robson;Antonio R. Perez-Atayde;Robert N. Husson

  • Transcription Regulation by the Mycobacterium tuberculosis Alternative Sigma Factor SigD and Its Role in Virulence

    Sahadevan Raman;Rohan Hazra;Christopher C. Dascher;Robert N. Husson

  • Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: An in vitro comparative study

    Takuma Shirasaka;Robert Yarchoan;Mary C. O'Brien;Robert N. Husson

  • The extracytoplasmic domain of the Mycobacterium tuberculosis Ser/Thr kinase PknB binds specific muropeptides and is required for PknB localization.

    Mushtaq Mir;Jinkeng Asong;Xiuru Li;Jessica Cardot

  • A mycobacterial extracytoplasmic function sigma factor involved in survival following stress.

    Qi-Long Wu;Dequan Kong;Kelvin Lam;Robert N. Husson

  • Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system

    Atul K. Singh;Xavier Carette;Lakshmi-Prasad Potluri;Jared D. Sharp

  • Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site

    Jason M. Schifano;Regina Edifor;Jared D. Sharp;Jared D. Sharp;Ming Ouyang

  • A Mycobacterial Extracytoplasmic Sigma Factor Involved in Survival following Heat Shock and Oxidative Stress

    Norvin D. Fernandes;Qi-long Wu;Dequan Kong;Xiaoling Puyang

  • RshA, an anti-sigma factor that regulates the activity of the mycobacterial stress response sigma factor SigH.

    Taeksun Song;Simon L. Dove;Kon Ho Lee;Robert N. Husson

  • The uraA locus and homologous recombination in Mycobacterium bovis BCG

    A Aldovini;R N Husson;R A Young

  • The Mycobacterium tuberculosis Extracytoplasmic-Function Sigma Factor SigL Regulates Polyketide Synthases and Secreted or Membrane Proteins and Is Required for Virulence

    Mi-Young Hahn;Sahadevan Raman;Mauricio Anaya;Robert N. Husson

  • Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli.

    F Oftung;A S Mustafa;R Husson;R A Young

  • Regulation of the SigH stress response regulon by an essential protein kinase in Mycobacterium tuberculosis

    Sang Tae Park;Choong-Min Kang;Robert N. Husson

Frequent Co-Authors

Philip A. Pizzo
Philip A. Pizzo Stanford University
David Venzon
David Venzon National Institutes of Health
Frank M. Balis
Frank M. Balis Children's Hospital of Philadelphia
Hanno Steen
Hanno Steen Boston Children's Hospital
Ofer Levy
Ofer Levy Boston Children's Hospital
John Quackenbush
John Quackenbush Harvard University
D. Branch Moody
D. Branch Moody Brigham and Women's Hospital
Eric J. Rubin
Eric J. Rubin Harvard University
Ronald W. Davis
Ronald W. Davis Stanford University

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