D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 16,937 135 World Ranking 9737 National Ranking 4280

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Genetics, Gene, Mycobacterium tuberculosis, Genome and Mutant. His studies link Secretion with Gene. His Mycobacterium tuberculosis research integrates issues from Antibiotic sensitivity, Biochemistry, Metabolic pathway and Microbiology.

His Genome research incorporates themes from Mutagenesis and Frameshift mutation. His Mutagenesis study incorporates themes from Pathogen and Deep sequencing. His Mutant research includes elements of Secretory protein, Proteomics, Bacterial genetics, Locus and Virulence.

His most cited work include:

  • Genes required for mycobacterial growth defined by high density mutagenesis (2002 citations)
  • Genetic Requirements for Mycobacterial Survival During Infection (1058 citations)
  • High-resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism (721 citations)

What are the main themes of his work throughout his whole career to date?

Christopher M. Sassetti focuses on Mycobacterium tuberculosis, Tuberculosis, Biochemistry, Gene and Genetics. His Mycobacterium tuberculosis study combines topics in areas such as Pathogen, Antibiotics, Microbiology, Immune system and Computational biology. In his study, which falls under the umbrella issue of Tuberculosis, Public health is strongly linked to Immunology.

Christopher M. Sassetti studied Biochemistry and Mycobacterium smegmatis that intersect with Cell biology. Genetics is represented through his Genome, Mutagenesis and Minimal genome research. The concepts of his Mutant study are interwoven with issues in Secretory protein and Virulence.

He most often published in these fields:

  • Mycobacterium tuberculosis (55.41%)
  • Tuberculosis (29.30%)
  • Biochemistry (33.12%)

What were the highlights of his more recent work (between 2018-2021)?

  • Mycobacterium tuberculosis (55.41%)
  • Tuberculosis (29.30%)
  • Cell biology (15.92%)

In recent papers he was focusing on the following fields of study:

Christopher M. Sassetti mainly focuses on Mycobacterium tuberculosis, Tuberculosis, Cell biology, Gene and Immunology. His Mycobacterium tuberculosis study combines topics from a wide range of disciplines, such as Genetics, Pathogen, Microbiology, T cell and Drug discovery. His work carried out in the field of Tuberculosis brings together such families of science as Efficacy, Antibiotics, In vivo and Vaccination.

The various areas that Christopher M. Sassetti examines in his Cell biology study include Cell wall, SIRT3, Metabolic pathway and Mycobacterium smegmatis. He works mostly in the field of Gene, limiting it down to topics relating to Cytokinesis and, in certain cases, Regulation of gene expression and Transcriptome. His Immunity and BCG vaccine study, which is part of a larger body of work in Immunology, is frequently linked to Bone marrow suppression, Linezolid and Intradermal route, bridging the gap between disciplines.

Between 2018 and 2021, his most popular works were:

  • Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes (43 citations)
  • Common Variants in the Glycerol Kinase Gene Reduce Tuberculosis Drug Efficacy. (25 citations)
  • The structure of the endogenous ESX-3 secretion system (24 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Tuberculosis, Mycobacterium tuberculosis, Immunology, Antibiotics and Drug resistance are his primary areas of study. The Tuberculosis study combines topics in areas such as T cell, Immunopathology, Granulocyte and Microbiology. Many of his studies on Mycobacterium tuberculosis involve topics that are commonly interrelated, such as Intracellular.

Many of his research projects under Immunology are closely connected to Hematopoietic stem cell with Hematopoietic stem cell, tying the diverse disciplines of science together. His research in Antibiotics intersects with topics in Gene and Genetic screen. His Gene research includes themes of In vivo, Efficacy, Combination therapy, Isoniazid and Drug discovery.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genes required for mycobacterial growth defined by high density mutagenesis

Christopher M. Sassetti;Dana H. Boyd;Eric J. Rubin.
Molecular Microbiology (2003)

2781 Citations

Genetic requirements for mycobacterial survival during infection

Christopher M. Sassetti;Eric J. Rubin.
Proceedings of the National Academy of Sciences of the United States of America (2003)

1446 Citations

High-resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

Jennifer E. Griffin;Jeffrey D. Gawronski;Michael A. DeJesus;Thomas R. Ioerger.
PLOS Pathogens (2011)

919 Citations

Mycobacterial persistence requires the utilization of host cholesterol

Amit K. Pandey;Christopher M. Sassetti.
Proceedings of the National Academy of Sciences of the United States of America (2008)

858 Citations

Comprehensive identification of conditionally essential genes in mycobacteria

Christopher M. Sassetti;Dana H. Boyd;Eric J. Rubin.
Proceedings of the National Academy of Sciences of the United States of America (2001)

686 Citations

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β.

Bibhuti B Mishra;Vijay A K Rathinam;Gregory W Martens;Amanda J Martinot.
Nature Immunology (2013)

524 Citations

Mutually dependent secretion of proteins required for mycobacterial virulence

S. M. Fortune;A. Jaeger;D. A. Sarracino;M. R. Chase.
Proceedings of the National Academy of Sciences of the United States of America (2005)

464 Citations

RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1.

J Clever;C Sassetti;T G Parslow.
Journal of Virology (1995)

386 Citations

Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis.

Michael A. DeJesus;Elias R. Gerrick;Weizhen Xu;Sae Woong Park.
Mbio (2017)

367 Citations

Identification of Podocalyxin-like Protein as a High Endothelial Venule Ligand for L-selectin: Parallels to CD34

Christopher Sassetti;Kirsten Tangemann;Mark S. Singer;David B. Kershaw.
Journal of Experimental Medicine (1998)

322 Citations

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