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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12952
World Ranking
10853
National Ranking
15

Research.com Recognitions

  • 2001 - Fellow, The World Academy of Sciences

Overview

Valerie Mizrahi is affiliated with the University of Cape Town in South Africa. Their research primarily focuses on tuberculosis and related infectious diseases, emphasizing molecular biology and biochemistry within the medical sciences.

The main fields of study for Mizrahi include Medicine and Biochemistry, Genetics and Molecular Biology. More specifically, their work spans subfields such as Infectious Diseases, Molecular Biology, Epidemiology, Surgery, and Neurology.

The major research topics Valerie Mizrahi has contributed to are:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Biochemical and Molecular Research
  • Neurological diseases and metabolism
  • CRISPR and Genetic Engineering
  • Cancer therapeutics and mechanisms
  • Bacterial Genetics and Biotechnology

Selected recent papers authored or co-authored by Mizrahi include:

  • "Arrayed CRISPRi and quantitative imaging describe the morphotypic landscape of essential mycobacterial genes," 2020, published in eLife
  • "Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols," 2021, published in PLoS Pathogens
  • "The Tuberculosis Drug Accelerator at year 10: what have we learned?" 2021, published in Nature Medicine
  • "Foam Cells Control Mycobacterium tuberculosis Infection," 2020, published in Frontiers in Microbiology
  • "Developing Synergistic Drug Combinations To Restore Antibiotic Sensitivity in Drug-Resistant Mycobacterium tuberculosis," 2021, published in Antimicrobial Agents and Chemotherapy

Frequent co-authors in Mizrahi's works include:

  • Digby F. Warner
  • Timothy J. de Wet
  • Clifton E. Barry
  • Anastasia Koch
  • Helena I. Boshoff

The scientist commonly publishes in journals and venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Infectious Diseases
  • eLife
  • PLoS Pathogens
  • Nature Medicine

Valerie Mizrahi has been recognized with the award of Fellow by The World Academy of Sciences in 2001.

Best Publications

  • DnaE2 Polymerase Contributes to In Vivo Survival and the Emergence of Drug Resistance in Mycobacterium tuberculosis

    Helena I.M. Boshoff;Helena I.M. Boshoff;Michael B. Reed;Clifton E. Barry;Valerie Mizrahi

  • Kinetic Mechanism of DNA Polymerase I (Klenow)

    R. D. Kuchta;V. Mizrahi;P. A. Benkovic;K. A. Johnson

  • The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice.

    John L. Dahl;Carl N. Kraus;Helena I. M. Boshoff;Bernard Doan

  • The Stringent Response of Mycobacterium tuberculosis Is Required for Long-Term Survival

    Todd P. Primm;Susan J. Andersen;Valerie Mizrahi;David Avarbock

  • Changes in energy metabolism of Mycobacterium tuberculosis in mouse lung and under in vitro conditions affecting aerobic respiration

    Lanbo Shi;Charles D. Sohaskey;Bavesh D. Kana;Stephanie Dawes

  • The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro.

    Bavesh D Kana;Bhavna G Gordhan;Katrina J Downing;Nackmoon Sung

  • The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo.

    Siobhan Cowley;Mary Ko;Neora Pick;Rayken Chow

  • Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations.

    Jennifer E. Griffin;Amit K. Pandey;Sarah A. Gilmore;Valerie Mizrahi

  • Identification of New Drug Targets and Resistance Mechanisms in Mycobacterium tuberculosis

    Thomas R. Ioerger;Theresa O’Malley;Reiling Liao;Kristine M. Guinn

  • Variation among Genome Sequences of H37Rv Strains of Mycobacterium tuberculosis from Multiple Laboratories

    Thomas R. Ioerger;Yicheng Feng;Krishna Ganesula;Xiaohua Chen

  • Functional Characterization of a Vitamin B12-Dependent Methylmalonyl Pathway in Mycobacterium tuberculosis: Implications for Propionate Metabolism during Growth on Fatty Acids

    Suzana Savvi;Digby F. Warner;Bavesh D. Kana;John D. McKinney

  • DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence

    Valerie Mizrahi;Susan J. Andersen

  • Mutants of Mycobacterium tuberculosis Lacking Three of the Five rpf-Like Genes Are Defective for Growth In Vivo and for Resuscitation In Vitro

    Katrina J. Downing;Vladimir V. Mischenko;Margarita O. Shleeva;Danielle I. Young

  • Mycobacterium tuberculosis and the host response

    Stefan H.E. Kaufmann;Stewart T. Cole;Valerie Mizrahi;Eric Rubin

  • Effects of Pyrazinamide on Fatty Acid Synthesis by Whole Mycobacterial Cells and Purified Fatty Acid Synthase I

    Helena I. Boshoff;Valerie Mizrahi;Clifton E. Barry

  • Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis.

    Bavesh D. Kana;Edward A. Weinstein;David Avarbock;Stephanie S. Dawes

  • Resuscitation-promoting factors as lytic enzymes for bacterial growth and signaling.

    Bavesh Davandra Kana;Valerie Mizrahi

  • Tuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy.

    Digby F. Warner;Valerie Mizrahi

  • Rate-limiting steps in the DNA polymerase I reaction pathway.

    V. Mizrahi;R. N. Henrie;J. F. Marlier;K. A. Johnson

  • Function of the Cytochrome bc1-aa3 Branch of the Respiratory Network in Mycobacteria and Network Adaptation Occurring in Response to Its Disruption

    Limenako Matsoso;Bavesh D Kana;Paul Crellin;David John Lea-Smith

Frequent Co-Authors

Clifton E. Barry
Clifton E. Barry National Institute of Allergy and Infectious Diseases
Gilla Kaplan
Gilla Kaplan Bill & Melinda Gates Foundation
Stephen J. Benkovic
Stephen J. Benkovic Pennsylvania State University
Harvey Rubin
Harvey Rubin University of Pennsylvania
Helena I. Boshoff
Helena I. Boshoff National Institutes of Health
Christopher M. Sassetti
Christopher M. Sassetti University of Massachusetts Chan Medical School
Kenneth A. Johnson
Kenneth A. Johnson The University of Texas at Austin
Jennifer Keiser
Jennifer Keiser Swiss Tropical and Public Health Institute
Tanya Parish
Tanya Parish Seattle Children's Hospital
Eric J. Rubin
Eric J. Rubin Harvard University

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