What is she best known for?
The fields of study she is best known for:
Helena I. Boshoff focuses on Mycobacterium tuberculosis, Biochemistry, Microbiology, Tuberculosis and Drug resistance.
Her Mycobacterium tuberculosis research includes themes of In vitro, Mechanism of action, Microarray analysis techniques, Immunology and Gene.
Her Biochemistry study deals with SQ109 intersecting with Nitroimidazole, Reactive nitrogen species, Intracellular, Primary metabolite and Nitroreductase.
The concepts of her Microbiology study are interwoven with issues in Heat shock protein and Bacterial genetics.
Helena I. Boshoff has researched Tuberculosis in several fields, including Microorganism, Metabolism, Bacterial growth and Microbial metabolism.
Her Drug resistance research includes themes of Polymerase and Pharmacology.
Her most cited work include:
- The spectrum of latent tuberculosis: rethinking the biology and intervention strategies (945 citations)
- The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action. (490 citations)
- PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release (419 citations)
What are the main themes of her work throughout her whole career to date?
Her primary scientific interests are in Mycobacterium tuberculosis, Biochemistry, Microbiology, Stereochemistry and Enzyme.
Her Mycobacterium tuberculosis research is within the category of Tuberculosis.
Her Tuberculosis study combines topics from a wide range of disciplines, such as Drug tolerance, Disease, Immunology and Intensive care medicine.
The concepts of her Microbiology study are interwoven with issues in Bacteria and Mutant, Gene, Virulence.
The Stereochemistry study combines topics in areas such as Nitroreductase, Structure–activity relationship, Antibacterial agent and Antimycobacterial.
Her work in Pharmacology addresses subjects such as Drug resistance, which are connected to disciplines such as Potency.
She most often published in these fields:
- Mycobacterium tuberculosis (63.79%)
- Biochemistry (37.36%)
- Microbiology (24.14%)
What were the highlights of her more recent work (between 2018-2021)?
- Mycobacterium tuberculosis (63.79%)
- Biochemistry (37.36%)
- In vitro (9.77%)
In recent papers she was focusing on the following fields of study:
Mycobacterium tuberculosis, Biochemistry, In vitro, Stereochemistry and Drug discovery are her primary areas of study.
Her Mycobacterium tuberculosis study is focused on Tuberculosis in general.
Her Tuberculosis research is multidisciplinary, incorporating elements of Pharmacophore, Drug target, Small Molecule Libraries and Computational biology.
Her research integrates issues of Antimycobacterial, Antimycobacterial Agents and Resistant tuberculosis in her study of Stereochemistry.
The study incorporates disciplines such as Multiple drug resistance and Protein biosynthesis in addition to Drug discovery.
Her work carried out in the field of Microbiology brings together such families of science as Drug repositioning and Virulence.
Between 2018 and 2021, her most popular works were:
- PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis (27 citations)
- Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development. (21 citations)
- Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline (11 citations)
In her most recent research, the most cited papers focused on:
Helena I. Boshoff mainly focuses on Mycobacterium tuberculosis, Microbiology, Biochemistry, Mycobacterium abscessus and Stereochemistry.
Helena I. Boshoff performs multidisciplinary study in Mycobacterium tuberculosis and Combination chemotherapy in her work.
Her Microbiology study frequently draws connections between adjacent fields such as Virulence.
Helena I. Boshoff works mostly in the field of Mycobacterium abscessus, limiting it down to topics relating to Transfer RNA and, in certain cases, Nontuberculous mycobacteria and Bacteria, as a part of the same area of interest.
Helena I. Boshoff combines subjects such as Mechanism of action, Biotin synthase, Acidomycin, Biotin biosynthesis and Antimycobacterial with her study of Stereochemistry.
Her Pathogen research incorporates themes from Oxidase test, Drug development, Respiratory chain and Tuberculosis.
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