World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
107
Citations
37439
World Ranking
549
National Ranking
328

Medicine

D-Index
107
Citations
37563
World Ranking
6319
National Ranking
3369

Overview

Gilla Kaplan is affiliated with the Bill & Melinda Gates Foundation in the United States. Their research primarily focuses on the field of medicine, with specific attention to epidemiology, infectious diseases, surgery, neurology, and immunology. The scientist's work spans multiple topics including tuberculosis research and epidemiology, Mycobacterium research and diagnosis, infectious diseases and tuberculosis, Pneumocystis jirovecii pneumonia detection and treatment, inhalation and respiratory drug delivery, multiple myeloma research and treatments, and peripheral neuropathies and disorders.

Kaplan has contributed to a number of research papers published in various scientific venues. Some recent publications include:

  • "Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols" (2021), published in PLoS Pathogens
  • "Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model" (2020), published in Frontiers in Cellular and Infection Microbiology
  • "Inoculum size and traits of the infecting clinical strain define the protection level against Mycobacterium tuberculosis infection in a rabbit model" (2020), published in European Journal of Immunology
  • "Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology" (2021), published in Communications Biology
  • "Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response" (2021), published in Frontiers in Microbiology

These papers highlight a detailed focus on tuberculosis and host-pathogen interactions, often utilizing animal models to study disease pathology and immune response mechanisms.

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, Communications Biology, Frontiers in Cellular and Infection Microbiology, and the European Journal of Immunology.

Collaborations are an integral part of Kaplan's work, with frequent coauthors including:

  • Afsal Kolloli
  • Selvakumar Subbian
  • Pooja Singh
  • Ranjeet Kumar
  • Alex Sigal

These coauthors have contributed to multiple publications together, indicating active research partnerships especially in infectious disease and immunology-related studies.

Best Publications

  • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

    E P Sampaio;E N Sarno;R Galilly;Z A Cohn

  • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

    A L Moreira;E P Sampaio;A Zmuidzinas;P Frindt

  • A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response

    Michael B. Reed;Pilar Domenech;Claudia Manca;Hua Su

  • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha.

    Laura G. Corral;Patrick A. J. Haslett;George W. Muller;Roger Chen

  • Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β

    Claudia Manca;Liana Tsenova;Amy Bergtold;Sherry Freeman

  • Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

    Karim C El Kasmi;Joseph E Qualls;John T Pesce;Amber M Smith

  • Thalidomide Costimulates Primary Human T Lymphocytes, Preferentially Inducing Proliferation, Cytokine Production, and Cytotoxic Responses in the CD8+ Subset

    Patrick A.J. Haslett;Laura G. Corral;Matthew Albert;Gilla Kaplan

  • Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro.

    Ralph M. Steinman;Gilla Kaplan;Margaret D. Witmer;Zanvil A. Cohn

  • Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin

    A Molloy;P Laochumroonvorapong;G Kaplan

  • Metformin as adjunct antituberculosis therapy

    Amit Singhal;Liu Jie;Pavanish Kumar;Gan Suay Hong

  • Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

    Mi-Jeong Kim;Helen C. Wainwright;Michael Locketz;Linda-Gail Bekker

  • Human dendritic cells. Enrichment and characterization from peripheral blood.

    WC Van Voorhis;LS Hair;RM Steinman;G Kaplan

  • Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

    Benjamin M. N. Kagina;Brian Abel;Thomas J. Scriba;Elizabeth J. Hughes

  • The Influence of Thalidomide on the Clinical and Immunologic Manifestation of Erythema Nodosum Leprosum

    Elizabeth P. Sampaio;Gilla Kaplan;Alice Miranda;Jose A. C. Nery

  • Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production

    George W. Muller;Roger Chen;Shaei-Yun Huang;Laura G. Corral

  • The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice.

    John L. Dahl;Carl N. Kraus;Helena I. M. Boshoff;Bernard Doan

  • Mycobacterium tuberculosis Growth at the Cavity Surface: a Microenvironment with Failed Immunity

    Gilla Kaplan;Frank A. Post;Andre L. Moreira;Helen Wainwright

  • Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates

    Claudia Manca;Liana Tsenova;Clifton E. Barry;Amy Bergtold

  • Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load

    Cheryl L. Day;Cheryl L. Day;Deborah A. Abrahams;Lesedi Lerumo;Esme Janse van Rensburg

  • Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy

    Carl F. Nathan;Gilla Kaplan;William R. Levis;Ali Nusrat

  • Thalidomide Exerts Its Inhibitory Action on Tumor Necrosis Factor oe by Enhancing mRNA Degradation By Andre L. Moreira,* Elizabeth P. Sampaio,*S Antonina Zmuidzinas,*

    Paula Frindt;Kendall A. Smith;Gilla Kaplan

Frequent Co-Authors

Zanvil A. Cohn
Zanvil A. Cohn Rockefeller University
Willem A. Hanekom
Willem A. Hanekom University College London
Linda-Gail Bekker
Linda-Gail Bekker University of Cape Town
Clifton E. Barry
Clifton E. Barry National Institute of Allergy and Infectious Diseases
Barry N. Kreiswirth
Barry N. Kreiswirth Center for Discovery and Innovation
Barun Mathema
Barun Mathema Columbia University
Euzenir Nunes Sarno
Euzenir Nunes Sarno Oswaldo Cruz Foundation
Frank A. Post
Frank A. Post King's College London
Elizabeth P. Sampaio
Elizabeth P. Sampaio National Institutes of Health
Thomas J. Scriba
Thomas J. Scriba University of Cape Town

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