Attilio Di Pietro

Overview

Best Publications

• Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein

  Gwenaelle Conseil;Helene Baubichon-Cortay;Guila Dayan;Jean-Michel Jault

  502
  Citations

• Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

  Abdelhakim Ahmed-Belkacem;Alexandre Pozza;Francisco Muñoz-Martínez;Susan E. Bates

  234
  Citations

• Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance

  Gergely Szakács;Matthew D. Hall;Michael M. Gottesman;Ahcène Boumendjel

  224
  Citations

• Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance

  Ahcène Boumendjel;Attilio Di Pietro;Charles Dumontet;Denis Barron

  224
  Citations

• Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis.

  Emmanuelle Steinfels;Cédric Orelle;‖ Jean-Raphaël Fantino;Olivier Dalmas

  179
  Citations

• The HPr kinase from Bacillus subtilis is a homo-oligomeric enzyme which exhibits strong positive cooperativity for nucleotide and fructose 1,6-bisphosphate binding.

  Jean-Michel Jault;Sonia Fieulaine;Sylvie Nessler;Philippe Gonzalo

  147
  Citations

• C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance.

  Gilles Comte;# Jean-Baptiste Daskiewicz;Christine Bayet;Gwenaëlle Conseil

  147
  Citations

• "Hysteretic" behavior and nucleotide binding sites of pig heart mitochondrial F1 adenosine 5'-triphosphatase

  Attilio Di Pietro;Francois Penin;Catherine Godinot;Daniele C. Gautheron

  142
  Citations

• Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1.

  Doriane Trompier;Xiu Bao Chang;Régis Barattin;Amaury Du Moulinet D'Hardemare

  138
  Citations

• Acridone derivatives: Design, synthesis, and inhibition of breast cancer resistance protein ABCG2

  Ahcene Boumendjel;Sira Macalou;Abdelhakim Ahmed-Belkacem;Madeleine Blanc

  120
  Citations

• Nonprenylated Rotenoids, a New Class of Potent Breast Cancer Resistance Protein Inhibitors

  Abdelhakim Ahmed-Belkacem;X Sira Macalou;X Francesca Borrelli;Raffaele Capasso

  119
  Citations

• Jatrophane diterpenes as modulators of multidrug resistance. Advances of structure-activity relationships and discovery of the potent lead pepluanin A.

  Gabriella Corea;Ernesto Fattorusso;Virginia Lanzotti;Riccardo Motti

  113
  Citations

• Investigation of Chalcones as Selective Inhibitors of the Breast Cancer Resistance Protein: Critical Role of Methoxylation in both Inhibition Potency and Cytotoxicity

  Glaucio Valdameri;Glaucio Valdameri;Charlotte Gauthier;Raphaël Terreux;Rémy Kachadourian

  109
  Citations

• ABCG2 Transports and Transfers Heme to Albumin through Its Large Extracellular Loop

  Elodie Desuzinges-Mandon;Ophélie Arnaud;Lorena Martinez;Frédéric Huché

  106
  Citations

• Jatrophane diterpenes as P-glycoprotein inhibitors. First insights of structure-activity relationships and discovery of a new, powerful lead.

  Gabriella Corea;Ernesto Fattorusso;Virginia Lanzotti;Orazio Taglialatela-Scafati

  106
  Citations

• Three-dimensional structure by cryo-electron microscopy of YvcC, an homodimeric ATP-binding cassette transporter from Bacillus subtilis.

  Mohamed Chami;Emmanuelle Steinfels;Cédric Orelle;Jean-Michel Jault

  101
  Citations

• Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy

  G. Corea;A. Di Pietro;C. Dumontet;C. Dumontet;E. Fattorusso

  95
  Citations

• Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.

  Glaucio Valdameri;Glaucio Valdameri;Estelle Genoux-Bastide;Basile Peres;Charlotte Gauthier

  94
  Citations

• Binding of steroid modulators to recombinant cytosolic domain from mouse P-glycoprotein in close proximity to the ATP site.

  Guila Dayan;§ Jean-Michel Jault;§ Hélène Baubichon-Cortay;Loris G. Baggetto

  92
  Citations

• (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1

  Thomas Perrotton;Doriane Trompier;Xiu Bao Chang;Attilio Di Pietro

  89
  Citations