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Medicine

D-Index
78
Citations
23167
World Ranking
18015
National Ranking
8980

Overview

Yashpal S. Kanwar is affiliated with Northwestern University in the United States and has contributed extensively to research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scholarly focus involves several subfields, with notable activity in Nephrology, Molecular Biology, Epidemiology, Pathology and Forensic Medicine, and Oncology.

The main research topics covered by Kanwar's work include:

  • Renal Diseases and Glomerulopathies
  • Chronic Kidney Disease and Diabetes
  • Inflammasome and immune disorders
  • Chemotherapy-induced organ toxicity mitigation
  • Dialysis and Renal Disease Management
  • Mitochondrial Function and Pathology
  • Peptidase Inhibition and Analysis

Kanwar has published numerous papers in well-recognized journals, with a particular emphasis on kidney-related diseases and molecular pathways affecting renal function. Selected recent publications include:

  • "New Pandemic: Obesity and Associated Nephropathy" (2021) in Frontiers in Medicine
  • "Regulated cell death in cisplatin-induced AKI: relevance of myo-inositol metabolism" (2021) in American Journal of Physiology-Renal Physiology
  • "A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection" (2022) in Journal of the American Society of Nephrology
  • "Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes" (2020) in Diabetes
  • "Modulation of gentamicin-induced acute kidney injury by myo-inositol oxygenase via the ROS/ALOX-12/12-HETE/GPR31 signaling pathway" (2022) in JCI Insight

The primary journals in which Kanwar has published most frequently include:

  • Journal of the American Society of Nephrology (11 publications)
  • Kidney International (5 publications)
  • American Journal of Physiology-Renal Physiology (4 publications)
  • Journal of Biological Chemistry (3 publications)
  • SSRN Electronic Journal (3 publications)

Frequent co-authors contributing to Kanwar's research network are:

  • Fei Deng (11 collaborations)
  • Isha Sharma (9 collaborations)
  • Yinhuai Wang (9 collaborations)
  • Zebin Deng (7 collaborations)
  • Vikram Aggarwal (7 collaborations)

Kanwar's research work combines clinical relevance and molecular mechanisms, often addressing kidney injury and diseases related to diabetes and immune dysfunction. Their contributions span a broad spectrum of biomedical research focused on understanding disease pathways, protective proteins, and metabolic regulation in renal pathology.

Best Publications

  • Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity

    Kazuyuki Hida;Jun Wada;Jun Eguchi;Hong Zhang;Hong Zhang

  • A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

    Yashpal S. Kanwar;Lin Sun;Ping Xie;Fu You Liu

  • Diabetic nephropathy: mechanisms of renal disease progression.

    Yashpal S. Kanwar;Jun Wada;Lin Sun;Ping Xie

  • Oxidative Stress in Diabetic Nephropathy

    N. Kashihara;Y. Haruna;V. K. Kondeti;Y. S. Kanwar

  • Biophysiology of glomerular filtration and proteinuria

    Yashpal S Kanwar

  • Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

    Jun Wada;Kosuke Ota;Anil Kumar;Elisabeth I. Wallner

  • Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

    Yachun Han;Xiaoxuan Xu;Chengyuan Tang;Peng Gao

  • 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy.

    Farhad R. Danesh;Mehran M. Sadeghi;Nail Amro;Carrie Philips

  • Amelioration of progressive renal injury by genetic manipulation of Klotho gene

    Yoshisuke Haruna;Naoki Kashihara;Minoru Satoh;Naruya Tomita

  • Collectrin, a collecting duct-specific transmembrane glycoprotein, is a novel homolog of ACE2 and is developmentally regulated in embryonic kidneys.

    Hong Zhang;Jun Wada;Kazuyuki Hida;Yoshinori Tsuchiyama

  • Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

    Ming Zhan;Irtaza M. Usman;Lin Sun;Yashpal S. Kanwar

  • Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane.

    Minoru Satoh;Anil Kumar;Yashpal S. Kanwar;Westley H. Reeves

  • Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

    Gang Liu;Beenu Kaw;Jayson Kurfis;Syed Rahmanuddin

  • Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

    Sun Hee Sung;Sun Hee Sung;Fuad N. Ziyadeh;Fuad N. Ziyadeh;Amy Wang;Petr E. Pyagay

  • ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice.

    M.J. Soler;J. Wysocki;M. Ye;J. Lloveras

  • Identification of a receptor for protein import into chloroplasts and its localization to envelope contact zones.

    Debkumar Pain;Yashpal S. Kanwar;Günter Blobel

  • Decreased de novo synthesis of glomerular proteoglycans in diabetes: biochemical and autoradiographic evidence.

    Yashpal S. Kanwar;Lionel J. Rosenzweig;Alfred Linker;Michael L. Jakubowski

  • Fibronectin localization in the rat glomerulus.

    Pierre J. Courtoy;Pierre J. Courtoy;Y S Kanwar;Y S Kanwar;R O Hynes;R O Hynes;M G Farquhar;M G Farquhar

  • Assembly of the glomerular filtration surface: Differentiation of anionic sites in glomerular capillaries of newborn rat kidney

    Westley H. Reeves;Yashpal S. Kanwar;Marilyn Gist Farquhar

  • Current status of the structural and functional basis of glomerular filtration and proteinuria.

    Yashpal S. Kanwar;Zheng Z. Liu;Naoki Kashihara;Elisabeth I. Wallner

Frequent Co-Authors

Hirofumi Makino
Hirofumi Makino Okayama University
Janardan K. Reddy
Janardan K. Reddy Northwestern University
Michael Abecassis
Michael Abecassis University of Arizona
Marilyn G. Farquhar
Marilyn G. Farquhar University of California, San Diego
Susan E. Quaggin
Susan E. Quaggin Northwestern University
Joshua Miller
Joshua Miller Northwestern University
Minoru Satoh
Minoru Satoh RMIT University
Jeffrey H. Miner
Jeffrey H. Miner Washington University in St. Louis
Deyu Fang
Deyu Fang Northwestern University
Arthur Veis
Arthur Veis Northwestern University

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