World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
9426
World Ranking
14050
National Ranking
5925

Overview

Goutam Ghosh Choudhury is affiliated with The University of Texas Health Science Center at San Antonio in the United States. They have a significant research footprint in the fields of Medicine, as well as Biochemistry, Genetics, and Molecular Biology. Their work extensively covers molecular biology and nephrology, with further contributions to physiology, immunology, and biochemistry.

The scientist's recent publications reflect a focus on signaling pathways, kidney function and injury, and metabolic diseases. Key papers include:

  • TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression, 2020, Journal of Biological Chemistry
  • Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury, 2021, Aging Cell
  • Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury, 2021, JCI Insight
  • β2-Adrenergic receptor agonist induced hepatic steatosis in mice: modeling nonalcoholic fatty liver disease in hyperadrenergic states, 2021, American Journal of Physiology-Endocrinology and Metabolism
  • High glucose-stimulated enhancer of zeste homolog-2 (EZH2) forces suppression of deptor to cause glomerular mesangial cell pathology, 2021, Cellular Signalling

The main topics addressed in Goutam Ghosh Choudhury's research are:

  • PI3K/AKT/mTOR signaling in cancer
  • Renal Diseases and Glomerulopathies
  • Ion channel regulation and function
  • Chronic Kidney Disease and Diabetes
  • Mast cells and histamine
  • Protein Kinase Regulation and GTPase Signaling
  • Sulfur Compounds in Biology

Frequent co-authors collaborating with the scientist include:

  • Balakuntalam S. Kasinath (12 publications)
  • Falguni Das (8 publications)
  • Nandini Ghosh-Choudhury (6 publications)
  • Hak Joo Lee (6 publications)
  • Kumar Sharma (6 publications)

Regular publishing venues where their work appears include:

  • Journal of Biological Chemistry (2 publications)
  • JCI Insight (2 publications)
  • Aging Cell
  • Diabetes
  • American Journal of Physiology-Endocrinology and Metabolism

Goutam Ghosh Choudhury's research predominantly investigates molecular mechanisms in renal physiology and pathology, with an emphasis on regulatory signaling pathways such as PI3K/AKT/mTOR. Their studies explore complex interactions between cellular signaling, ion channels, and metabolic stressors that contribute to kidney injury and related diseases.

Best Publications

  • Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells.

    Yves Gorin;Jill M. Ricono;Nam Ho Kim;Basant Bhandari

  • Requirement of BMP-2-induced Phosphatidylinositol 3-Kinase and Akt Serine/Threonine Kinase in Osteoblast Differentiation and Smad-dependent BMP-2 Gene Transcription

    Nandini Ghosh-Choudhury;Sherry L. Abboud;Riko Nishimura;Anthony Celeste

  • A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy.

    Myung Ja Lee;Denis Feliers;Meenalakshmi M. Mariappan;Kavithalakshmi Sataranatarajan

  • Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

    F. Marra;A. Gentilini;M. Pinzani;Goutam Ghosh Choudhury

  • MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.

    Nirmalya Dey;Falguni Das;Meenalakshmi M. Mariappan;Chandi Charan Mandal

  • Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN.

    Lenin Mahimainathan;Falguni Das;Balachandar Venkatesan;Goutam Ghosh Choudhury

  • Simvastatin induces derepression of PTEN expression via NFκB to inhibit breast cancer cell growth

    Nayana Ghosh-Choudhury;Chandi Charan Mandal;Nandini Ghosh-Choudhury;Goutam Ghosh Choudhury

  • Angiotensin II-induced ERK1/ERK2 activation and protein synthesis are redox-dependent in glomerular mesangial cells.

    Yves Gorin;Jill M. Ricono;Brent Wagner;Nam Ho Kim

  • Statin-induced Ras Activation Integrates the Phosphatidylinositol 3-Kinase Signal to Akt and MAPK for Bone Morphogenetic Protein-2 Expression in Osteoblast Differentiation *

    Nandini Ghosh-Choudhury;Chandi Charan Mandal;Goutam Ghosh Choudhury

  • PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF

    Goutam Ghosh Choudhury;C. Karamitsos;James Hernandez;Alessandra Gentilini

  • Mammalian Target of Rapamycin Regulates Nox4- Mediated Podocyte Depletion in Diabetic Renal Injury

    Assaad A. Eid;Assaad A. Eid;Bridget M. Ford;Basant Bhandary;Rita de Cassia Cavaglieri

  • Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA.

    J H Pierce;E Di Marco;G W Cox;D Lombardi

  • Hydrogen Sulfide Inhibits High Glucose-induced Matrix Protein Synthesis by Activating AMP-activated Protein Kinase in Renal Epithelial Cells

    Hak Joo Lee;Meenalakshmi M. Mariappan;Denis Feliers;Rita C. Cavaglieri

  • TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion

    Nirmalya Dey;Nandini Ghosh-Choudhury;Nandini Ghosh-Choudhury;Balakuntalam S. Kasinath;Balakuntalam S. Kasinath;Goutam Ghosh Choudhury;Goutam Ghosh Choudhury

  • Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase

    Yves Gorin;Nam Ho Kim;Denis Feliers;Basant Bhandari

  • Regulation of elongation phase of mRNA translation in diabetic nephropathy: Amelioration by rapamycin

    Kavithalakshmi Sataranatarajan;Meenalakshmi M. Mariappan;Myung Ja Lee;Denis Feliers

  • Simvastatin Prevents Skeletal Metastasis of Breast Cancer by an Antagonistic Interplay between p53 and CD44

    Chandi Charan Mandal;Nayana Ghosh-Choudhury;Toshi Yoneda;Goutam Ghosh Choudhury;Goutam Ghosh Choudhury

  • Fish oil prevents breast cancer cell metastasis to bone.

    Chandi Charan Mandal;Triparna Ghosh-Choudhury;Toshi Yoneda;Goutam Ghosh Choudhury

  • VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells

    Denis Feliers;Xiaoyan Chen;Xiaoyan Chen;Nese Akis;Nese Akis;Goutam Ghosh Choudhury;Goutam Ghosh Choudhury

  • Inactivation of Platelet-derived Growth Factor Receptor by the Tumor Suppressor PTEN Provides a Novel Mechanism of Action of the Phosphatase

    Lenin Mahimainathan;Goutam Ghosh Choudhury;Goutam Ghosh Choudhury

Frequent Co-Authors

Hanna E. Abboud
Hanna E. Abboud The University of Texas Health Science Center at San Antonio
Fabio Marra
Fabio Marra University of Florence
Victor L. Sylvia
Victor L. Sylvia United States Air Force
Sunil K. Ahuja
Sunil K. Ahuja The University of Texas Health Science Center at San Antonio
Veronica Galvan
Veronica Galvan University of Oklahoma Health Sciences Center
Arlan Richardson
Arlan Richardson University of Oklahoma Health Sciences Center
Christopher G. Kevil
Christopher G. Kevil Louisiana State University Health Sciences Center Shreveport
Riko Nishimura
Riko Nishimura Osaka University
Bysani Chandrasekar
Bysani Chandrasekar University of Missouri
Peter C. Melby
Peter C. Melby The University of Texas Medical Branch at Galveston

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to many flexible online degrees and rewarding career pathways in the USA. If you’re seeking a direct impact on patient care, consider rn to bsn online programs to boost your nursing credentials efficiently while working.

For those interested in leadership roles, a degree in healthcare management allows you to transition smoothly into health administration and management positions, often at an accelerated pace.

Mental health is a growing focus within healthcare and science. If this area interests you, the fastest pmhnp program can quickly prepare you to become a psychiatric mental health nurse practitioner.

Nutrition integrates closely with biology and biochemistry. If your passion lies here, there are accelerated dietitian programs available online to help you qualify faster and make a direct impact on community health.

Each of these online degrees offers flexibility and career growth, making them excellent options for students in biology and biochemistry looking to specialize or diversify their careers.

Best Scientists Citing Goutam Ghosh Choudhury

Trending Scientists

Recently Published Articles