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Medicine

D-Index
96
Citations
50676
World Ranking
9488
National Ranking
257

Overview

Daisuke Koya is affiliated with Kanazawa Medical University in Japan and has contributed extensively in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Endocrinology, Diabetes and Metabolism, Molecular Biology, Nephrology, Physiology, and Epidemiology.

Their work covers main topics including Diabetes Treatment and Management, Chronic Kidney Disease and Diabetes, Autophagy in Disease and Therapy, Hormonal Regulation and Hypertension, Sirtuins and Resveratrol in Medicine, Peptidase Inhibition and Analysis, and Pancreatic Function and Diabetes.

Recent publications by Daisuke Koya include:

  • Autophagy in metabolic disease and ageing, 2021, Nature Reviews Endocrinology
  • Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules, 2020, JCI Insight
  • Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy, 2021, Nature Communications
  • Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis, 2020, Autophagy
  • CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats, 2020, Aging

Frequent co-authors collaborating with Daisuke Koya include:

  • Munehiro Kitada
  • Keizo Kanasaki
  • Yoshio Ogura
  • Yuta Takagaki
  • Swayam Prakash Srivastava

The scientist has regularly published in journals such as:

  • Journal of Diabetes Investigation
  • Diabetology International
  • Diabetes Obesity and Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Aging

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Protein kinase C activation and the development of diabetic complications.

    Daisuke Koya;George L. King

  • Amelioration of Vascular Dysfunctions in Diabetic Rats by an Oral PKC β Inhibitor

    Hidehiro Ishii;Michael R. Jirousek;Daisuke Koya;Chikako Takagi

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

    Shinji Kume;Takashi Uzu;Kihachiro Horiike;Masami Chin-Kanasaki

  • Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.

    D Koya;M R Jirousek;Y W Lin;H Ishii

  • Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes

    Daisuke Koya;Masakazu Haneda;Hiroko Nakagawa;Keiji Isshiki

  • SIRT1 and insulin resistance.

    Fengxia Liang;Shinji Kume;Daisuke Koya

  • A new classification of Diabetic Nephropathy 2014: a report from Joint Committee on Diabetic Nephropathy

    Masakazu Haneda;Kazunori Utsunomiya;Daisuke Koya;Tetsuya Babazono

  • Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway.

    Munehiro Kitada;Shinji Kume;Noriko Imaizumi;Daisuke Koya

  • Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen

    Keizo Kanasaki;Sen Shi;Megumi Kanasaki;Jianhua He

  • Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus

    Hidehiro Ishii;Daisuke Koya;G. L. King

  • Effects of Antioxidants in Diabetes-Induced Oxidative Stress in the Glomeruli of Diabetic Rats

    Daisuke Koya;Kazuyuki Hayashi;Munehiro Kitada;Atsunori Kashiwagi

  • Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy.

    Atsuko Tagawa;Mako Yasuda;Shinji Kume;Kosuke Yamahara

  • Role of Altered Renal Lipid Metabolism in the Development of Renal Injury Induced by a High-Fat Diet

    Shinji Kume;Takashi Uzu;Shin-ichi Araki;Toshiro Sugimoto

  • SIRT1 Inhibits Transforming Growth Factor β-Induced Apoptosis in Glomerular Mesangial Cells via Smad7 Deacetylation

    Shinji Kume;Masakazu Haneda;Keizo Kanasaki;Toshiro Sugimoto

  • Structural and functional changes in the kidneys of high-fat diet-induced obese mice

    Naoko Deji;Shinji Kume;Shin-ichi Araki;Mariko Soumura

  • Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol.

    D Koya;I K Lee;H Ishii;H Kanoh

  • Progression of diabetic nephropathy.

    Ryuichi Kikkawa;Daisuke Koya;Masakazu Haneda

Frequent Co-Authors

Atsunori Kashiwagi
Atsunori Kashiwagi Shiga University of Medical Science
George L. King
George L. King Harvard University
Hirofumi Makino
Hirofumi Makino Okayama University
Shiro Maeda
Shiro Maeda University of the Ryukyus
Ken Inoki
Ken Inoki University of Michigan–Ann Arbor
Hirotaka Watada
Hirotaka Watada Juntendo University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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