World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
62
Citations
20770
World Ranking
2823
National Ranking
13

Overview

Olaf Rötzschke is affiliated with the Agency for Science, Technology and Research in Singapore. Their research spans multiple fields, primarily Medicine and Biochemistry, Genetics and Molecular Biology. Key subfields include Infectious Diseases, Molecular Biology, Immunology, Oncology, and Neurology.

The scientist's work covers various main topics such as:

  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Lymphoma Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Long-Term Effects of COVID-19
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers

Several recent papers exemplify their research output:

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression, 2021, Nature Genetics
  • Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity, 2020, Clinical Infectious Diseases
  • Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19, 2020, Nature Communications
  • Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour, 2021, Nature Human Behaviour
  • The role of IgA in COVID-19, 2020, Brain Behavior and Immunity

Olaf Rötzschke frequently collaborates with several researchers, including:

  • Bernett Lee
  • Anand Kumar Andiappan
  • Kia Joo Puan
  • Peter A.C. 't Hoen
  • Joyce B. J. van Meurs

The scientist often publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Journal of Allergy and Clinical Immunology
  • Allergy
  • Cancer Research

Best Publications

  • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules.

    K Falk;O Rötzschke;S Stevanović;G Jung

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression

    Giovanna Borsellino;Markus Kleinewietfeld;Diletta Di Mitri;Alexander Sternjak

  • Peptides Naturally Presented by MHC Class I Molecules

    Hans-Georg Rammensee;Kirsten Falk;Olaf Rotzschke

  • Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells.

    Olaf Rötzschke;Kirsten Falk;Karl Deres;Hansjörg Schild

  • Exact prediction of a natural T cell epitope.

    Olaf Rötzschke;Kirsten Falk;Stefan Stevanovic;Günther Jung

  • Cellular peptide composition governed by major histocompatibility complex class I molecules

    Kirsten Falk;Olaf Rötzschke;Hans-Georg Rammensee

  • Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

    Võsa U;Claringbould A;Westra H;Bonder Mj

  • CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

    Markus Kleinewietfeld;Fabiola Puentes;Giovanna Borsellino;Luca Battistini

  • Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast.

    K Falk;O Rötzschke;K Deres;J Metzger

  • Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y.

    Olaf Rötzschke;Kirsten Falk;Hans-Joachim Wallny;Stefan Faath

  • Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules

    Kirsten Falk;Olaf Rötzschke;Stefan Stevanovíc;Günther Jung

  • On the nature of peptides involved in T cell alloreactivity.

    O Rötzschke;K Falk;S Faath;H G Rammensee

  • Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway

    Olaf Rötzschke;Kirsten Falk

  • Several HLA alleles share overlapping peptide specificities.

    J Sidney;M F del Guercio;S Southwood;V H Engelhard

  • Establishing Criteria for Human Mesenchymal Stem Cell Potency

    Rebekah M. Samsonraj;Bina Rai;Padmapriya Sathiyanathan;Kia Joo Puan

  • MHC molecules as peptide receptors

    Hans-Georg Rammensee;Kirsten Falk;Olaf Rötzschke

  • Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma

    Hweixian Leong Penny;Je Lin Sieow;Giulia Adriani;Wei Hseun Yeap

  • Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

    Yiu‐Wing Kam;Fok‐Moon Lum;Fok‐Moon Lum;Teck‐Hui Teo;Wendy W. L. Lee

  • Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity.

    Barnaby E Young;Barnaby E Young;Sean W X Ong;Lisa F P Ng;Danielle E Anderson

  • Dominant aromatic/aliphatic C-terminal anchor in HLA-B^*2702 and B^*2705 peptide motifs

    Olaf Rötzschke;Kirsten Falk;Stefan Stevanovic;Volker Gnau

Frequent Co-Authors

Kirsten Falk
Kirsten Falk Max Delbrück Center for Molecular Medicine
Günther Jung
Günther Jung University of Tübingen
Stefan Stevanovic
Stefan Stevanovic University of Tübingen
Lisa F. P. Ng
Lisa F. P. Ng Agency for Science, Technology and Research
De Yun Wang
De Yun Wang National University of Singapore
Anis Larbi
Anis Larbi Agency for Science, Technology and Research
Michael Poidinger
Michael Poidinger Murdoch Children's Research Institute
Jack L. Strominger
Jack L. Strominger Harvard University
Jianjun Liu
Jianjun Liu Genome Institute of Singapore
Hans-Georg Rammensee
Hans-Georg Rammensee University of Tübingen

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