Peptide, MHC class I, Major histocompatibility complex, Immunology and Genetics are his primary areas of study. The various areas that Olaf Rötzschke examines in his Peptide study include Consensus sequence, Peptide sequence, HLA-DR locus and Stereochemistry. His research in Peptide sequence intersects with topics in Amino acid, C-terminus, Molecular biology, Allele and Epitope.
To a larger extent, Olaf Rötzschke studies Antigen with the aim of understanding MHC class I. The Major histocompatibility complex study combines topics in areas such as Cytotoxic T cell and Antigen presentation. His study explores the link between Immunology and topics such as Cell biology that cross with problems in Antigen processing.
The scientist’s investigation covers issues in Immunology, Major histocompatibility complex, Peptide, Genetics and MHC class I. His study in Immunology concentrates on Immune system, T cell, FOXP3, Antibody and Inflammation. His Major histocompatibility complex study integrates concerns from other disciplines, such as Molecular biology, Cytotoxic T cell, Antigen presentation and Cell biology.
His Peptide research focuses on Stereochemistry and how it connects with MHC class II. His study in MHC class I focuses on MHC restriction and Antigen processing. His MHC restriction research includes elements of CD74 and Transporter associated with antigen processing.
Olaf Rötzschke spends much of his time researching Immunology, Natural killer T cell, Lymphoma, Pathogenesis and Immune system. His Immunology study frequently draws connections between related disciplines such as Transcriptome. The study incorporates disciplines such as Pembrolizumab, Refractory and Virology in addition to Lymphoma.
Olaf Rötzschke combines subjects such as Disease, Parkinson's disease and Gut–brain axis with his study of Pathogenesis. His research integrates issues of Proinflammatory cytokine, Viral culture and Antibody in his study of Immune system. His Flow cytometry study incorporates themes from T cell, Hypoxia and CD8.
His primary scientific interests are in Immunology, Lymphoma, Natural killer T cell, Refractory and Pembrolizumab. His Immunology research is multidisciplinary, incorporating elements of Necrosis and Stem cell. His Lymphoma study combines topics from a wide range of disciplines, such as Blockade, Cancer research and Oncology.
His Natural killer T cell research incorporates themes from Immunohistochemistry, Internal medicine, Cohort and Progressive disease. His work carried out in the field of Virus brings together such families of science as Apoptosis, Transcriptome, Interferon gamma and Pathogenesis. His Flow cytometry research includes themes of Peripheral blood mononuclear cell, In vitro, Cytokine, Progenitor cell and Chemokine.
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Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules.
Kirsten Falk;Olaf Rötzschke;Stefan Stevanovié;Günther Jung.
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
Giovanna Borsellino;Markus Kleinewietfeld;Diletta Di Mitri;Alexander Sternjak.
Peptides Naturally Presented by MHC Class I Molecules
Hans-Georg Rammensee;Kirsten Falk;Olaf Rotzschke.
Annual Review of Immunology (1993)
Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells.
Olaf Rötzschke;Kirsten Falk;Karl Deres;Hansjörg Schild.
Exact prediction of a natural T cell epitope.
Olaf Rötzschke;Kirsten Falk;Stefan Stevanovic;Günther Jung.
European Journal of Immunology (1991)
Cellular peptide composition governed by major histocompatibility complex class I molecules
Kirsten Falk;Olaf Rötzschke;Hans-Georg Rammensee.
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.
Markus Kleinewietfeld;Fabiola Puentes;Giovanna Borsellino;Luca Battistini.
Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast.
K Falk;O Rötzschke;K Deres;J Metzger.
Journal of Experimental Medicine (1991)
Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y.
Olaf Rotzschke;Kirsten Falk;Hans-Joachim Wallny;Stefan Faath.
Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules
Kirsten Falk;Olaf Rötzschke;Stefan Stevanovíc;Günther Jung.
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