What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Genetics
His primary areas of investigation include Molecular biology, Internal medicine, Endocrinology, Genetically modified mouse and Transgene.
His Molecular biology research includes elements of Mutant, Gene expression, Gene, Cre recombinase and Protein structure.
Thomas Rülicke has included themes like Diabetes mellitus, microRNA and Cellular differentiation in his Internal medicine study.
His research investigates the connection between Genetically modified mouse and topics such as Virology that intersect with problems in Pathogenesis, Amyloid and Nucleic acid.
His work deals with themes such as Scrapie, Phenotype, Neurodegeneration, PRNP and Knockout mouse, which intersect with Transgene.
Thomas Rülicke combines subjects such as Protease and Cell biology with his study of Scrapie.
His most cited work include:
- Molecular and neuronal substrate for the selective attenuation of anxiety. (824 citations)
- Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. (789 citations)
- Experimental autoimmune encephalomyelitis repressed by microglial paralysis. (590 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Transgene, Molecular biology, Immunology and Genetically modified mouse.
His Cell biology research is multidisciplinary, relying on both Embryonic stem cell, Stromal cell, Pathology and Immune system.
His research investigates the link between Transgene and topics such as Knockout mouse that cross with problems in Nervous system and Ectopic expression.
His work carried out in the field of Molecular biology brings together such families of science as Cell culture and Gene expression.
His Immunology study deals with Cytotoxic T cell intersecting with Antigen and T cell.
Thomas Rülicke combines subjects such as Scrapie, Endocrinology, Internal medicine and Virology with his study of Genetically modified mouse.
He most often published in these fields:
- Cell biology (25.65%)
- Transgene (17.39%)
- Molecular biology (17.83%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (17.39%)
- Leukemia (11.30%)
- Stem cell (15.22%)
In recent papers he was focusing on the following fields of study:
Thomas Rülicke spends much of his time researching Cancer research, Leukemia, Stem cell, CD38 and Progenitor cell.
His Cancer research research is multidisciplinary, incorporating perspectives in Leukemia lymphoma, STAT5, Transgene and Gain of function.
His biological study focuses on Genetically modified mouse.
His Stem cell study incorporates themes from Multiple forms, Chronic myelomonocytic leukemia and Bone marrow.
In his study, Lymphotoxin and Immune system is strongly linked to Cell, which falls under the umbrella field of Progenitor cell.
His work in Phenotype covers topics such as Regulation of gene expression which are related to areas like Cell biology.
Between 2017 and 2021, his most popular works were:
- Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations (27 citations)
- Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp. (20 citations)
- Structural and functional consequences of the STAT5BN642H driver mutation. (16 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Enzyme
Thomas Rülicke mainly investigates Leukemia, Cancer research, Internal medicine, Endocrinology and Myeloid leukemia.
He has researched Leukemia in several fields, including CD135, Imatinib, Pharmacology and CD38.
His study in Cancer research is interdisciplinary in nature, drawing from both Haematopoiesis, Steatosis, CD20, Lymphoma and CD33.
His Lymphoma research is multidisciplinary, incorporating elements of Genetically modified mouse, Transgene, Mutant and SH2 domain.
Internal medicine and Diabetes mellitus are commonly linked in his work.
His studies in Myeloid leukemia integrate themes in fields like Tyrosine kinase, ABL and Vildagliptin.
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