What is he best known for?
The fields of study he is best known for:
- Gene
- Signal transduction
- Phosphorylation
Edward Y. Skolnik focuses on Biochemistry, Cell biology, SH2 domain, SH3 domain and GRB2.
His is doing research in Phosphatidylinositol, Pleckstrin homology domain, Proto-oncogene tyrosine-protein kinase Src, Tyrosine phosphorylation and Signal transducing adaptor protein, both of which are found in Biochemistry.
His Cell biology research integrates issues from Membrane potential, Cell surface receptor and Ion channel.
Much of his study explores SH2 domain relationship to Insulin Receptor Substrate Proteins.
His SH3 domain study incorporates themes from SOS1 Protein, Anti-apoptotic Ras signalling cascade and GRB2 Adaptor Protein.
His GRB2 research is multidisciplinary, incorporating perspectives in Epidermal growth factor and IRS2, Insulin receptor, GRB10, Insulin receptor substrate.
His most cited work include:
- The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling (1382 citations)
- Phosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulation. (875 citations)
- Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. (822 citations)
What are the main themes of his work throughout his whole career to date?
Edward Y. Skolnik mainly focuses on Cell biology, Biochemistry, Kinase, Phosphorylation and Molecular biology.
The various areas that he examines in his Cell biology study include Caenorhabditis elegans and T-cell receptor.
Biochemistry is represented through his SH2 domain, Nucleoside Diphosphate Kinase B, Pleckstrin homology domain, Peptide sequence and Epidermal growth factor research.
His work in SH2 domain addresses issues such as SH3 domain, which are connected to fields such as GRB7 and GRB2.
Edward Y. Skolnik combines subjects such as Tumor necrosis factor alpha, Ubiquitin ligase and Cytokine with his study of Kinase.
His Phosphorylation study combines topics in areas such as Nucleoside-diphosphate kinase, Potassium channel and Histidine.
He most often published in these fields:
- Cell biology (46.32%)
- Biochemistry (35.79%)
- Kinase (23.16%)
What were the highlights of his more recent work (between 2012-2020)?
- Cell biology (46.32%)
- Phosphorylation (20.00%)
- Biochemistry (35.79%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Cell biology, Phosphorylation, Biochemistry, Internal medicine and Phosphatase.
Specifically, his work in Cell biology is concerned with the study of Kinase.
His research in Phosphorylation intersects with topics in Nucleoside-diphosphate kinase, Potassium channel and Histidine.
His Biochemistry study frequently draws connections between related disciplines such as Acquired immune system.
His biological study spans a wide range of topics, including Diabetes mellitus, Endocrinology and Diabetic retinopathy.
His Phosphatase research is multidisciplinary, incorporating elements of Histidine kinase, Mutant and Distal convoluted tubule.
Between 2012 and 2020, his most popular works were:
- Ion Channels in Innate and Adaptive Immunity (289 citations)
- Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. (63 citations)
- Metabolic Inflexibility Impairs Insulin Secretion and Results In MODY-like Diabetes in Triple FoxO-Deficient Mice (56 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Signal transduction
- Phosphorylation
His main research concerns Phosphorylation, Nucleoside-diphosphate kinase, Phosphatase, Biochemistry and Cell biology.
His work carried out in the field of Nucleoside-diphosphate kinase brings together such families of science as Protein phosphorylation, Serine and Histidine.
His Phosphatase study integrates concerns from other disciplines, such as Caenorhabditis elegans, Pi, Mutant and Endocytosis, Pinocytosis.
The study of Biochemistry is intertwined with the study of Immune system in a number of ways.
His Cell biology research incorporates elements of Acquired immune system, Cell culture, Innate immune system and Voltage-dependent calcium channel.
The Voltage-dependent calcium channel study combines topics in areas such as Histidine kinase, Reabsorption, Distal convoluted tubule and Molecular biology.
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