World's Best Scientists 2026 revealed!
William A. Coetzee

William A. Coetzee

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
9674
World Ranking
14583
National Ranking
6113

Overview

William A. Coetzee is affiliated with New York University in the United States. Their scientific work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in several subfields including Molecular Biology, Pathology and Forensic Medicine, Physiology, Immunology, and Cardiology and Cardiovascular Medicine.

Coetzee's research addresses a broad range of topics, offering insights into areas such as:

  • Cardiac Ischemia and Reperfusion
  • Ion channel regulation and function
  • Adenosine and Purinergic Signaling
  • Cardiac electrophysiology and arrhythmias
  • Immune Cell Function and Interaction
  • Receptor Mechanisms and Signaling
  • Pancreatic function and diabetes

The scientist has published papers in a variety of journals, with frequent publications appearing in the Biophysical Journal, American Journal of Physiology-Cell Physiology, Frontiers in Immunology, Science Immunology, and Nature Immunology.

Notable recent papers include:

  • "Targeting Piezo1 unleashes innate immunity against cancer and infectious disease," 2020, Science Immunology
  • "The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling," 2022, Nature Immunology
  • "Palmitoylation of the K ATP channel Kir6.2 subunit promotes channel opening by regulating PIP 2 sensitivity," 2020, Proceedings of the National Academy of Sciences
  • "Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc," 2020, eLife
  • "Subcellular trafficking and endocytic recycling of KATP channels," 2022, American Journal of Physiology-Cell Physiology

Frequent collaborators include Hua-Qian Yang, Ivan Gando, Natalie Samper, Stefan Feske, and Tomoe Y. Nakamura.

Best Publications

  • Molecular Diversity of K+ Channels

    William A. Coetzee;Yimy Amarillo;Joanna Chiu;Alan Chow

  • Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

    John W. Calvert;William A. Coetzee;David J. Lefer

  • KATP Channels in the Cardiovascular System.

    Monique N. Foster;William A. Coetzee

  • Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells

    Shekhar Srivastava;Zhai Li;Kyung Ko;Papiya Choudhury

  • Subcellular [Ca2+]i gradients during excitation-contraction coupling in newborn rabbit ventricular myocytes.

    Peter S. Haddock;William A. Coetzee;Emily Cho;Lisa Porter

  • Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm

    Marina Cerrone;Jerome Montnach;Xianming Lin;Yan Ting Zhao

  • The Glycolytic Enzymes, Glyceraldehyde-3-phosphate Dehydrogenase, Triose-phosphate Isomerase, and Pyruvate Kinase Are Components of the KATP Channel Macromolecular Complex and Regulate Its Function

    Piyali Dhar-Chowdhury;Maddison D. Harrell;Sandra Y. Han;Danuta Jankowska

  • cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells

    Guoxin Kang;Oleg G. Chepurny;Brian Malester;Michael J. Rindler

  • A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents

    Tomoe Y. Nakamura;David J. Pountney;Ander Ozaita;Sumon Nandi

  • Short Communication: Flecainide Exerts an Antiarrhythmic Effect in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia by Increasing the Threshold for Triggered Activity

    Nian Liu;Marco Denegri;Yanfei Ruan;José Everardo Avelino-Cruz

  • Differential Structure of Atrial and Ventricular KATP Atrial KATP Channels Require SUR1

    Thomas P. Flagg;Harley T. Kurata;Ricard Masia;George Caputa

  • Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature

    Alison Morrissey;Erika Rosner;Jennifer Lanning;Lavanya Parachuru

  • Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis

    Deborah U. Frank;Kandis L. Carter;Kirk R. Thomas;R. Michael Burr

  • The regulation of ion channels and transporters by glycolytically derived ATP

    P. Dhar-Chowdhury;B. Malester;P. Rajacic;W. A. Coetzee

  • Modulation of Kv4 channels, key components of rat ventricular transient outward K+ current, by PKC

    Tomoe Y. Nakamura;William A. Coetzee;Eleazar Vega-Saenz De Miera;Michael Artman

  • Effects of thyroid hormone on action potential and repolarizing currents in rat ventricular myocytes.

    Zhuo-Qian Sun;Kaie Ojamaa;William A. Coetzee;Michael Artman

  • Calmodulin kinase II inhibition prevents arrhythmias in RyR2R4496C+/− mice with catecholaminergic polymorphic ventricular tachycardia

    Nian Liu;Yanfei Ruan;Marco Denegri;Tiziana Bachetti

  • The Phosphatidylinositol 3-Phosphate Phosphatase Myotubularin- Related Protein 6 (MTMR6) Is a Negative Regulator of the Ca2+-Activated K+ Channel KCa3.1

    Shekhar Srivastava;Zhai Li;Lin Lin;GongXin Liu

  • Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic β‐cells and rat INS‐1 cells

    Guoxin Kang;Colin A. Leech;Oleg G. Chepurny;William A. Coetzee

  • KATP channels of primary human coronary artery endothelial cells consist of a heteromultimeric complex of Kir6.1, Kir6.2, and SUR2B subunits

    Hidetada Yoshida;Jonathan E. Feig;Alison Morrissey;Ioana A. Ghiu

Frequent Co-Authors

Lionel H. Opie
Lionel H. Opie University of Cape Town
Bernardo Rudy
Bernardo Rudy New York University
David J. Hearse
David J. Hearse St Thomas' Hospital
Edward Y. Skolnik
Edward Y. Skolnik New York University
David J. Lefer
David J. Lefer Louisiana State University Health Sciences Center New Orleans
Silvia G. Priori
Silvia G. Priori University of Pavia
Ravichandran Ramasamy
Ravichandran Ramasamy New York University
Mark A. Magnuson
Mark A. Magnuson Vanderbilt University
Thomas A. Neubert
Thomas A. Neubert New York University
Colin G. Nichols
Colin G. Nichols Washington University in St. Louis

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a degree in Biology or Biochemistry opens the door to a variety of rewarding career paths. Many students use these majors as foundations for further study in health-related fields. For those interested in the practical application of biological sciences within healthcare, there are flexible online programs to consider.

For example, if you are looking to advance from a medical assistant to a licensed practical nurse, there are tailored medical assistant to lpn programs available online. These can accelerate your transition into more advanced nursing roles.

If you want to begin your studies remotely, an online bachelor's degree in biology offers a comprehensive scientific foundation, while online nursing programs provide streamlined routes to clinical and patient care positions.

Nutrition is another area closely tied to biology and biochemistry. Consider exploring the best online nutrition programs if you are interested in the science of food, health, and wellness. Each of these online pathways can help you build skills for an expanding job market in science and healthcare.

Best Scientists Citing William A. Coetzee

Trending Scientists