World's Best Scientists 2026 revealed!
Michail V. Sitkovsky

Michail V. Sitkovsky

D-Index & Metrics

Immunology

D-Index
75
Citations
21859
World Ranking
1978
National Ranking
966

Overview

Michail V. Sitkovsky is affiliated with Northeastern University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Their work also spans various subfields such as Physiology, Immunology, Biomedical Engineering, Oncology, and Cancer Research.

The main topics studied by Sitkovsky focus on Adenosine and Purinergic Signaling, Immune Cell Function and Interaction, Nanoplatforms for cancer theranostics, Cancer, Hypoxia, and Metabolism, Immune cells in cancer, Cannabis and Cannabinoid Research, and Polyomavirus and related diseases.

Among recent papers authored or coauthored by Sitkovsky are:

  • Lessons from the A2A Adenosine Receptor Antagonist-Enabled Tumor Regression and Survival in Patients with Treatment-Refractory Renal Cell Cancer, 2020, Cancer Discovery
  • Antihypoxic oxygenation agents with respiratory hyperoxia to improve cancer immunotherapy, 2020, Journal of Clinical Investigation
  • Oxygen-Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors, 2021, Advanced Functional Materials
  • Therapeutic effects of adenosine in high flow 21% oxygen aereosol in patients with Covid19-pneumonia, 2020, PLoS ONE
  • Oxygen-generating cryogels restore T cell-mediated cytotoxicity in hypoxic tumors, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors collaborate with Sitkovsky on various publications and include Stephen Hatfield, Thibault Colombani, Loek J. Eggermont, Mahboobeh Rezaeeyazdi, and Adnan Memić.

Publications by Sitkovsky appear across multiple venues, with the most frequent being bioRxiv (Cold Spring Harbor Laboratory), Advanced Functional Materials, Cancer Discovery, Journal of Clinical Investigation, and PLoS ONE.

Best Publications

  • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage.

    Akio Ohta;Michail Sitkovsky

  • A2A adenosine receptor protects tumors from antitumor T cells

    Akio Ohta;Elieser Gorelik;Simon J. Prasad;Franca Ronchese

  • Animal Models of sepsis: setting the stage

    Jon A. Buras;Bernhard Holzmann;Michail Sitkovsky

  • Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A2A receptors.

    Michail V. Sitkovsky;Dmitriy Lukashev;Sergey Apasov;Hidefumi Kojima

  • Purinergic Signaling during Inflammation

    Holger K. Eltzschig;Michail V. Sitkovsky;Simon C. Robson

  • Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors.

    Michail Sitkovsky;Dmitriy Lukashev

  • Role of A2a Extracellular Adenosine Receptor-Mediated Signaling in Adenosine-Mediated Inhibition of T-Cell Activation and Expansion

    Steve Huang;Sergey Apasov;Masahiro Koshiba;Michail Sitkovsky

  • Immunological mechanisms of the antitumor effects of supplemental oxygenation.

    Stephen M. Hatfield;Jorgen Kjaergaard;Dmitriy Lukashev;Taylor H. Schreiber

  • Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions.

    Charles C. Caldwell;Hidefumi Kojima;Dmitriy Lukashev;John Armstrong

  • The development and immunosuppressive functions of CD4+ CD25+ FoxP3+ regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway

    Akio Ohta;Radhika Kini;Akiko Ohta;Meenakshi Subramanian

  • Immunomodulatory and neuroprotective effects of inosine

    György Haskó;Michail V. Sitkovsky;Csaba Szabó

  • Extracellular adenosine-mediated modulation of regulatory T cells.

    Akio Ohta;Michail Sitkovsky

  • The 'danger' sensors that STOP the immune response: the A2 adenosine receptors?

    Michail V. Sitkovsky;Akio Ohta

  • Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury.

    Manfred Thiel;Alexander Chouker;Alexander Chouker;Akio Ohta;Akio Ohta;Edward Jackson

  • Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia.

    Michail V. Sitkovsky;Jorgen Kjaergaard;Dmitriy Lukashev;Akio Ohta

  • Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice

    Hidefumi Kojima;Hua Gu;Saeko Nomura;Charles C. Caldwell

  • A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments

    Akio Ohta;Akiko Ohta;Manasa Madasu;Radhika Kini

  • Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists.

    Michail Sitkovsky;Stephen M Hatfield;Robert G. Abbott;Bryan Belikoff

  • Ecto-ATPase activity in cytolytic T-lymphocytes. Protection from the cytolytic effects of extracellular ATP.

    A Filippini;R E Taffs;T Agui;M V Sitkovsky

  • T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response

    Michail V. Sitkovsky

  • Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes.

    Guido Trenn;Hajime Takayama;Michail V. Sitkovsky

Frequent Co-Authors

Charles C. Caldwell
Charles C. Caldwell University of Cincinnati
Frank A. Redegeld
Frank A. Redegeld Utrecht University
Edwin K. Jackson
Edwin K. Jackson University of Pittsburgh
Daniel G. Remick
Daniel G. Remick Boston University
Holger K. Eltzschig
Holger K. Eltzschig The University of Texas Health Science Center at Houston
György Haskó
György Haskó Columbia University
Mark A. Exley
Mark A. Exley Brigham and Women's Hospital
Jerrold M. Ward
Jerrold M. Ward National Institutes of Health
Michael R. Blackburn
Michael R. Blackburn The University of Texas Health Science Center at Houston

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, pursuing related online degrees can open doors to diverse healthcare careers. Nurse Practitioner programs often appeal to students seeking a blend of clinical expertise and patient care. Finding the easiest NP program can help streamline this educational journey without compromising on quality.

Mental health is increasingly recognized as a vital area within immunological research and care. Online PMHNP programs with clinical placement offer valuable hands-on experience, ensuring graduates are practice-ready. Additionally, many aspiring clinicians look for cheap psych NP programs to balance education costs with career ambitions.

Understanding financial outcomes is crucial when choosing a degree path. Transparency about DNP salary by state helps candidates make informed decisions, highlighting regions where their advanced nursing degrees might yield higher pay.

By exploring these options, students can align their interests in Immunology with practical and affordable education pathways, enhancing their potential to contribute meaningfully to healthcare.

Best Scientists Citing Michail V. Sitkovsky

Trending Scientists

Recently Published Articles