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Immunology

D-Index
63
Citations
11380
World Ranking
3072
National Ranking
1438

Overview

Claire A. Chougnet is affiliated with Cincinnati Children's Hospital Medical Center in the United States. Their research focuses primarily on the fields of Medicine and Immunology and Microbiology, with notable engagement in subfields such as Immunology, Epidemiology, Pulmonary and Respiratory Medicine, Surgery, and Obstetrics and Gynecology.

The scientist has contributed extensively to topics including:

  • Preterm Birth and Chorioamnionitis
  • Neonatal Respiratory Health Research
  • Reproductive System and Pregnancy
  • Immune Cell Function and Interaction
  • Congenital Diaphragmatic Hernia Studies
  • T-cell and B-cell Immunology
  • Pregnancy and Preeclampsia Studies

Frequent coauthors collaborating with Claire A. Chougnet include Suhas G. Kallapur, Pietro Presicce, Lisa A. Miller, Alan H. Jobe, and David A. Hildeman.

Their scholarly output is published in several venues with multiple contributions to bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, JCI Insight, The Journal of Immunology, and Open Forum Infectious Diseases.

Selected recent papers authored or co-authored by Claire A. Chougnet are:

  • IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression (2020, Science Advances)
  • Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease (2022, Scientific Reports)
  • TNF-Signaling Modulates Neutrophil-Mediated Immunity at the Feto-Maternal Interface During LPS-Induced Intrauterine Inflammation (2020, Frontiers in Immunology)
  • Pulmonary Consequences of Prenatal Inflammatory Exposures: Clinical Perspective and Review of Basic Immunological Mechanisms (2020, Frontiers in Immunology)
  • The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota (2022, Science Translational Medicine)

Best Publications

  • Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy

    Bernice Lo;Kejian Zhang;Wei Lu;Lixin Zheng

  • Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients

    Jan Andersson;Adriano Boasso;Jakob Nilsson;Rui Zhang

  • Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation

    Celine S. Lages;Isabelle Suffia;Paula A. Velilla;Bin Huang

  • HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

    Jakob Nilsson;Adriano Boasso;Paula Andrea Velilla;Rui Zhang

  • The placental membrane microbiome is altered among subjects with spontaneous preterm birth with and without chorioamnionitis.

    Amanda L. Prince;Jun Ma;Paranthaman S. Kannan;Manuel Alvarez

  • CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.

    Jean-Philippe Herbeuval;Jean-Charles Grivel;Adriano Boasso;Andrew W. Hardy

  • Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques.

    Zdenek Hel;David Venzon;Monita Poudyal;Wen Po Tsai

  • Defective antigen-presenting cell function in human neonates.

    Paula A. Velilla;Maria T. Rugeles;Claire A. Chougnet

  • TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells.

    Jean-Philippe Herbeuval;Adriano Boasso;Jean-Charles Grivel;Andrew W. Hardy

  • Natural Regulatory T Cells and Persistent Viral Infection

    Shuo Li;Eric James Gowans;Eric James Gowans;Claire Chougnet;Magdalena Plebanski

  • CTLA-4 blockade decreases TGF-β, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques

    Anna Hryniewicz;Adriano Boasso;Yvette Edghill-Smith;Monica Vaccari

  • Bronchopulmonary Dysplasia and Perinatal Characteristics Predict 1-Year Respiratory Outcomes in Newborns Born at Extremely Low Gestational Age: A Prospective Cohort Study

    Roberta L. Keller;Rui Feng;Sara B. DeMauro;Thomas Ferkol

  • Human Glioma-Induced Immunosuppression Involves Soluble Factor(s) That Alters Monocyte Cytokine Profile and Surface Markers

    Jian-Ping Zou;Lorri A. Morford;Claire Chougnet;Amy R. Dix

  • Homeostasis and function of regulatory T cells in aging

    Jana Raynor;Celine S Lages;Hesham Shehata;David A Hildeman

  • Recombinant vaccine-induced protection against the highly pathogenic simian immunodeficiency virus SIV(mac251): dependence on route of challenge exposure.

    J. Benson;C. Chougnet;M. Robert-Guroff;D. Montefiori

  • Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging Dendritic Cells Is Associated with Mitochondrial Dysfunction

    Claire A. Chougnet;Robert I. Thacker;Hesham M. Shehata;Cassandra M. Hennies

  • Molecular Analysis of Decreased Interleukin-12 Production in Persons Infected with Human Immunodeficiency Virus

    Claire Chougnet;Thomas A. Wynn;Mario Clerici;Alan L. Landay

  • Partial restoration of T‐cell function in aged mice by in vitro blockade of the PD‐1/ PD‐L1 pathway

    Celine S. Lages;Ian Lewkowich;Alyssa Sproles;Marsha Wills-Karp

  • A Major Role for Bim in Regulatory T Cell Homeostasis

    Claire A. Chougnet;Pulak Tripathi;Celine S. Lages;Jana Raynor

  • Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero.

    Ofelia A. Olivero;Gene M. Shearer;Claire A. Chougnet;Andrea A.S. Kovacs

  • Effector Role of Neonatal Hepatic CD8+ Lymphocytes in Epithelial Injury and Autoimmunity in Experimental Biliary Atresia

    Pranavkumar Shivakumar;Gregg Sabla;Sujit Mohanty;Monica McNeal

Frequent Co-Authors

Suhas G. Kallapur
Suhas G. Kallapur University of California, Los Angeles
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Alan H. Jobe
Alan H. Jobe Cincinnati Children's Hospital Medical Center
David A. Hildeman
David A. Hildeman Cincinnati Children's Hospital Medical Center
Alan L. Landay
Alan L. Landay The University of Texas Medical Branch at Galveston
Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
Jun Ma
Jun Ma Sun Yat-sen University
Harold A. Kessler
Harold A. Kessler Rush University Medical Center
Miriam C. Poirier
Miriam C. Poirier National Institutes of Health
Andrea Kovacs
Andrea Kovacs University of Southern California

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