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Ryan J. Uitti

Ryan J. Uitti

D-Index & Metrics

Medicine

D-Index
94
Citations
30957
World Ranking
10519
National Ranking
5413

Overview

Ryan J. Uitti is affiliated with the Mayo Clinic in the United States and has a strong focus on neurological and genetic research. Their work spans multiple fields, primarily Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. The scientist has contributed extensively to the subfields of Neurology, Molecular Biology, Physiology, Cellular and Molecular Neuroscience, and Genetics.

Their main research topics encompass Parkinson's Disease mechanisms and treatments, neurological diseases and metabolism, neurological disorders and treatments, genetic neurodegenerative diseases, Alzheimer's disease research and treatments, mitochondrial function and pathology, and lysosomal storage disorders research.

Ryan J. Uitti has frequently collaborated with several researchers, including Zbigniew K. Wszołek, Owen A. Ross, Dennis W. Dickson, Shunsuke Koga, and Alexandra I. Soto-Beasley.

They have published papers in multiple venues, with the most frequent being Parkinsonism & Related Disorders, Neurology, bioRxiv (Cold Spring Harbor Laboratory), Acta Neuropathologica Communications, and Movement Disorders.

Significant recent papers include:

  • Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome, 2021, Nature Communications
  • Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study, 2020, The Lancet Neurology
  • Neuroimaging Advances in Deep Brain Stimulation: Review of Indications, Anatomy, and Brain Connectomics, 2020, American Journal of Neuroradiology
  • Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution, 2020, Neurology
  • Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson's disease, 2024, Nature Genetics

Best Publications

  • Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

    Alexander Zimprich;Alexander Zimprich;Saskia Biskup;Petra Leitner;Peter Lichtner

  • VPS35 Mutations in Parkinson Disease

    Carles Vilariño-Güell;Christian Wider;Owen A. Ross;Justus C. Dachsel

  • Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy

    Günter U. Höglinger;Nadine M. Melhem;Dennis W. Dickson;Patrick M A Sleiman

  • Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

    Jennifer Gass;Ashley Cannon;Ian R. Mackenzie;Bradley Boeve

  • Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

    Oliver Cooper;Hyemyung Seo;Shaida Andrabi;Cristina Guardia-Laguarta

  • Mutations in the colony stimulating factor 1 receptor ( CSF1R ) gene cause hereditary diffuse leukoencephalopathy with spheroids

    Rosa Rademakers;Matt Baker;Alexandra M Nicholson;Nicola J Rutherford

  • TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

    Sruti Rayaprolu;Bianca Mullen;Matt Baker;Timothy Lynch

  • Alterations of T-lymphocyte populations in Parkinson disease.

    Yasuhiko Baba;Ataru Kuroiwa;Ryan J. Uitti;Zbigniew K. Wszolek

  • Translation initiator EIF4G1 mutations in familial Parkinson disease

    Marie Christine Chartier-Harlin;Marie Christine Chartier-Harlin;Justus C. Dachsel;Carles Vilariño-Güell;Sarah J. Lincoln

  • Deep brain stimulation: preoperative issues.

    Anthony E. Lang;Jean Luc Houeto;Paul Krack;Cynthia Kubu

  • Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.

    Owen A. Ross;Alexandra I. Soto-Ortolaza;Michael G. Heckman;Jan O. Aasly

  • Widespread Alterations of α-Synuclein in Multiple System Atrophy

    D.W. Dickson;W.-K. Liu;J. Hardy;M. Farrer

  • PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.

    John R. Adams;Hinke van Netten;Michael Schulzer;Edwin Mak

  • Autosomal dominant parkinsonism associated with variable synuclein and tau pathology

    Zbigniew K. Wszolek;R. F. Pfeiffer;Y. Tsuboi;R. J. Uitti

  • When DLB, PD, and PSP masquerade as MSA An autopsy study of 134 patients

    Shunsuke Koga;Naoya Aoki;Ryan J. Uitti;Jay A. van Gerpen

  • Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia

    Rosa Rademakers;Jason L. Eriksen;Matt Baker;Todd Robinson

  • Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodies

    T. J. Ferman;B. F. Boeve;G. E. Smith;S. C. Lin

  • A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease

    Karl Kieburtz;Bernard Ravina;Bernard Ravina;Wendy R. Galpern;Barbara Tilley

  • Nonamnestic mild cognitive impairment progresses to dementia with Lewy bodies

    Tanis J. Ferman;Glenn E. Smith;Kejal Kantarci;Bradley F. Boeve

  • Hypersexuality with antiparkinsonian therapy.

    Ryan J. Uitti;C. M. Tanner;A. H. Rajput;C. G. Goetz

Frequent Co-Authors

Owen A. Ross
Owen A. Ross Mayo Clinic
Matthew J. Farrer
Matthew J. Farrer University of Florida
Rosa Rademakers
Rosa Rademakers University of Antwerp
Bradley F. Boeve
Bradley F. Boeve Mayo Clinic
Ronald C. Petersen
Ronald C. Petersen University of Pennsylvania
Keith A. Josephs
Keith A. Josephs Mayo Clinic
Thomas Gasser
Thomas Gasser University of Tübingen

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