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Cosima T. Baldari

Cosima T. Baldari

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
24172
World Ranking
8469
National Ranking
225

Overview

Cosima T. Baldari is affiliated with the University of Siena in Italy. Their research primarily encompasses immunology and microbiology, biochemistry, genetics, molecular biology, and medicine. Subfields of focus include immunology, molecular biology, oncology, genetics, and cell biology. The main topics covered in their work involve immune cell function and interaction, T-cell and B-cell immunology, CAR-T cell therapy research, chronic lymphocytic leukemia research, immunotherapy and immune responses, cancer immunotherapy and biomarkers, and cellular transport and secretion.

They have published extensively, with notable frequent publication venues including:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cell and Developmental Biology
  • International Journal of Molecular Sciences

Among their recent papers are:

  • "The Expanding Arsenal of Cytotoxic T Cells" (2022, Frontiers in Immunology)
  • "Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes" (2022, Nature Communications)
  • "Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells" (2020, Science Signaling)
  • "Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells" (2021, Frontiers in Cell and Developmental Biology)
  • "Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability" (2022, European Journal of Medicinal Chemistry)

Their frequent coauthors include:

  • Nagaja Capitani
  • Laura Patrussi
  • Francesca Finetti
  • Chiara Cassioli
  • Anna Onnis

Cosima T. Baldari has contributed to book publications as well, notably a title published by Springer International Publishing: "Cellular Primary Immunodeficiencies" (2021).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease.

    M M D'Elios;M Manghetti;M De Carli;F Costa

  • The Helicobacter pylori Vacuolating Toxin Inhibits T Cell Activation by Two Independent Mechanisms

    Marianna Boncristiano;Silvia Rossi Paccani;Silvia Barone;Cristina Ulivieri

  • Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse.

    Francesca Finetti;Silvia Rossi Paccani;Maria Giovanna Riparbelli;Emiliana Giacomello

  • Different cytokine profile and antigen-specificity repertoire in Helicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer.

    M M D'Elios;M Manghetti;F Almerigogna;A Amedei

  • A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae.

    C. Baldari;J. A. H. Murray;P. Ghiara;G. Cesareni

  • Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.

    A Heguy;C T Baldari;G Macchia;J L Telford

  • The p66Shc Longevity Gene Is Silenced through Epigenetic Modifications of an Alternative Promoter

    Andrea Ventura;Lucilla Luzi;Sonia Pacini;Cosima T. Baldari

  • Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling.

    Silvia Rossi Paccani;Fiorella Tonello;Raffaella Ghittoni;Mariarita Natale

  • T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions.

    Marisa Benagiano;Annalisa Azzurri;Alessandra Ciervo;Amedeo Amedei

  • Anthrax toxins: a paradigm of bacterial immune suppression

    Cosima T. Baldari;Fiorella Tonello;Silvia Rossi Paccani;Cesare Montecucco

  • Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.

    Raffaella Ghittoni;Laura Patrussi;Katja Pirozzi;Michela Pellegrini

  • Plasmids pEMBLY: new single-stranded shuttle vectors for the recovery and analysis of yeast DNA sequences.

    C. Baldari;G. Cesareni

  • Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line.

    M. Rosetto;Y. Engstrom;C.T. Baldari;J.L. Telford

  • Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering.

    Luca Bini;Sonia Pacini;Sabrina Liberatori;Silvia Valensin

  • p66SHC Promotes Apoptosis and Antagonizes Mitogenic Signaling in T Cells

    Sonia Pacini;Michela Pellegrini;Enrica Migliaccio;Laura Patrussi

  • A motif within the T cell receptor α-chain constant region connecting peptide domain controls antigen responsiveness

    B.Thomas Bäckström;Elisabetta Milia;Annick Peter;Beltran Jaureguiberry

  • Isolation of cloned genes differentially expressed at early and late stages of Drosophila embryonic development

    G. Scherer;J. Telford;C. Baldari;V. Pirrotta

  • Impaired T-cell regulation of B-cell growth in Helicobacter pylori–related gastric low-grade MALT lymphoma

    Mario M. D'Elios;Amedeo Amedei;Marta Manghetti;Francesco Costa

Frequent Co-Authors

John L. Telford
John L. Telford GlaxoSmithKline (Italy)
Mario Milco D'Elios
Mario Milco D'Elios University of Siena
Pier Giuseppe Pelicci
Pier Giuseppe Pelicci European Institute of Oncology
Amedeo Amedei
Amedeo Amedei University of Florence
Gianfranco Del Prete
Gianfranco Del Prete University of Florence
Rolando Cimaz
Rolando Cimaz University of Milan
Luisa Lanfrancone
Luisa Lanfrancone European Institute of Oncology
Francesco Cecconi
Francesco Cecconi Catholic University of the Sacred Heart
Romano Dallai
Romano Dallai University of Siena
Cesare Montecucco
Cesare Montecucco University of Padua

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