World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
13575
World Ranking
18222
National Ranking
581

Overview

Luisa Lanfrancone is affiliated with the European Institute of Oncology in Italy and has an extensive publication record primarily focused on biochemistry, genetics, molecular biology, and medicine. Their research spans multiple subfields including molecular biology, oncology, cancer research, immunology, and biophysics.

Their recent research output includes notable papers published between 2021 and 2023, featuring topics related to cancer biology, melanoma, and molecular pathways. Selected recent papers include:

  • TFEB and TFE3 drive kidney cystogenesis and tumorigenesis, 2023, EMBO Molecular Medicine
  • Regulation of LncRNAs in Melanoma and Their Functional Roles in the Metastatic Process, 2022, Cells
  • Targeting the USP7/RRM2 axis drives senescence and sensitizes melanoma cells to HDAC/LSD1 inhibitors, 2022, Cell Reports
  • Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation, 2021, EMBO Reports
  • Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma, 2022, Cell Reports

Their work addresses several main topics, such as:

  • Melanoma and MAPK Pathways
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Epigenetics and DNA Methylation
  • Immunotherapy and Immune Responses
  • RNA Research and Splicing
  • Cancer Cells and Metastasis

The frequent coauthors who have collaborated with Luisa Lanfrancone include:

  • Federica Marocchi
  • Pier Giuseppe Pelicci
  • Daniela Bossi
  • Pier Francesco Ferrucci
  • Fiorenza Lotti

Lanfrancone's publications are often found in journals with a focus on translational and molecular research. The most frequent publication venues include:

  • Journal of Translational Medicine
  • Cancer Research
  • Cell Reports
  • EMBO Reports
  • Nature Communications

The scientist's body of work covers a significant number of publications with an emphasis on the molecular mechanisms underlying cancer progression, therapeutic resistance, and biomarker identification. Their research contributions support broader efforts in understanding melanoma biology and developing potential diagnostic and treatment strategies in oncology.

Best Publications

  • The p66shc adaptor protein controls oxidative stress response and life span in mammals

    Enrica Migliaccio;Marco Giorgio;Simonetta Mele;Giuliana Pelicci

  • A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.

    Giuliana Pelicci;Luisa Lanfrancone;Francesco Grignani;Jane McGlade

  • Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Annette T. Byrne;Denis G. Alférez;Frédéric Amant;Daniela Annibali

  • Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells.

    Fabio Re;Adriana Zanetti;Marina Sironi;Nadia Polentarutti

  • A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis.

    Mirella Trinei;Marco Giorgio;Angelo Cicalese;Sara Barozzi

  • Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

    Enrica Migliaccio;Simonetta Mele;Anna E. Salcini;Giuliana Pelicci

  • High-Efficiency Gene Transfer and Selection of Human Hematopoietic Progenitor Cells with a Hybrid EBV/Retroviral Vector Expressing the Green Fluorescence Protein

    Francesco Grignani;Todd Kinsella;Amedea Mencarelli;Mauro Valtieri

  • The Life Span Determinant p66Shc Localizes to Mitochondria Where It Associates with Mitochondrial Heat Shock Protein 70 and Regulates Trans-membrane Potential

    Francesca Orsini;Enrica Migliaccio;Maurizio Moroni;Cristina Contursi

  • Not all Shc's roads lead to Ras

    Laura Bonfini;Enrica Migliaccio;Giuliana Pelicci;Luisa Lanfrancone

  • Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.

    Nives Jonjić;Giuseppe Peri;Sergio Bernasconi;Francesca Luisa Sciacca

  • Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc

    Stephen M. Dilworth;Charlotte E. P. Brewster;Michael D. Jones;Luisa Lanfrancone

  • The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein

    G Pelicci;Silvia Giordano;Z Zhen;Ae Salcini

  • Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

    Mohamed Elgendy;Marco Cirò;Amir Hosseini;Jakob Weiszmann

  • Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1.

    L Lanfrancone;D Boraschi;P Ghiara;B Falini

  • Amplification of the c-myb oncogene in a case of human acute myelogenous leukemia

    Pier Giuseppe Pelicci;Luisa Lanfrancone;Michel D. Brathwaite;Sandra R. Wolman

  • A New Variant Anaplastic Lymphoma Kinase (ALK)-Fusion Protein (ATIC-ALK) in a Case of ALK-positive Anaplastic Large Cell Lymphoma

    Mirella Trinei;Luisa Lanfrancone;Elias Campo;Karen Pulford

  • Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness

    Mercedes Rodriguez;Ewa Aladowicz;Luisa Lanfrancone;Colin R. Goding

  • Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth.

    Chiara Di Malta;Diletta Siciliano;Alessia Calcagni;Jlenia Monfregola

  • Expression of Adhesion Molecules and Chemotactic Cytokines in Cultured Human Mesothelial Cells By Nives Jonji6,* Giuseppe Peri,* Sergio Bernasconi,*

    Francesca Luisa Sciacca;Francesco Colotta;PierGiuseppe Pelicci;Luisa Lanfrancone

  • splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway

    Enrica Migliaccio;Simonetta Mele;Giuliana Pelicci;Tony Pawson

Frequent Co-Authors

Pier Giuseppe Pelicci
Pier Giuseppe Pelicci European Institute of Oncology
Saverio Minucci
Saverio Minucci European Institute of Oncology
Cosima T. Baldari
Cosima T. Baldari University of Siena
Giuseppe Curigliano
Giuseppe Curigliano University of Milan
Giancarlo Pruneri
Giancarlo Pruneri University of Milan
Tony Pawson
Tony Pawson University of Toronto
Enzo Medico
Enzo Medico University of Turin
Gioacchino Natoli
Gioacchino Natoli European Institute of Oncology
Giulio Draetta
Giulio Draetta The University of Texas MD Anderson Cancer Center
Myriam Alcalay
Myriam Alcalay University of Milan

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