World's Best Scientists 2026 revealed!
Lloyd W. Ruddock

Lloyd W. Ruddock

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
9848
World Ranking
17572
National Ranking
125

Lloyd W. Ruddock publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Lloyd W. Ruddock sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 128 publications — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Lloyd W. Ruddock D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Lloyd W. Ruddock sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Lloyd W. Ruddock is affiliated with the University of Oulu in Finland. Their research contributions span key areas within biochemistry, genetics, and molecular biology, with a total of 61 publications in these fields. Medicine is another area of focus, accounting for 20 publications.

The scientist's work includes extensive investigation within molecular biology and cell biology, which are reflected in 26 and 16 publications respectively. Additional subfields include radiology, nuclear medicine and imaging, genetics, and ecology.

The research topics addressed cover:

  • Endoplasmic Reticulum Stress and Disease
  • Monoclonal and Polyclonal Antibodies Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Bacteriophages and microbial interactions
  • Protein purification and stability
  • Transgenic Plants and Applications
  • Autophagy in Disease and Therapy

Frequent publication venues include:

  • Journal of Biological Chemistry
  • Scientific Reports
  • Trends in biotechnology
  • International Journal of Molecular Sciences
  • Protein Expression and Purification

Notable recent publications by Lloyd W. Ruddock are:

  • "Microbial protein cell factories fight back?" (2021) in Trends in biotechnology
  • "A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein" (2020) in PLoS Genetics
  • "Mutation in protein disulfide isomerase A3 causes neurodevelopmental defects by disturbing endoplasmic reticulum proteostasis" (2021) in The EMBO Journal
  • "So you want to express your protein in Escherichia coli?" (2021) in Essays in Biochemistry
  • "Production of Extracellular Matrix Proteins in the Cytoplasm of E. coli: Making Giants in Tiny Factories" (2020) in International Journal of Molecular Sciences

The scientist collaborates frequently with peers, including:

  • Mirva J. Saaranen
  • Aatir A. Tungekar
  • Rosario Recacha
  • Angel Castillo-Corujo
  • Anil A. Sohail

Best Publications

  • The human protein disulphide isomerase family: substrate interactions and functional properties

    Lars Ellgaard;Lloyd W. Ruddock

  • Protein disulfide isomerase: a critical evaluation of its function in disulfide bond formation.

    Feras Hatahet;Lloyd W. Ruddock

  • The b′ domain provides the principal peptide‐binding site of protein disulfide isomerase but all domains contribute to binding of misfolded proteins

    Peter Klappa;Lloyd W. Ruddock;Nigel J. Darby;Nigel J. Darby;Robert B. Freedman

  • Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation

    Christoph Reinhardt;Marie Luise Von Brühl;Davit Manukyan;Lenka Grahl

  • N-glycan processing in ER quality control.

    Lloyd W. Ruddock;Maurizio Molinari

  • Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation

    Van Dat Nguyen;Mirva J. Saaranen;Anna-Riikka Karala;Anna-Kaisa Lappi

  • A molecular specificity code for the three mammalian KDEL receptors

    Irina Raykhel;Heli Alanen;Kirsi Salo;Jaana Jurvansuu

  • Protein disulfide isomerases exploit synergy between catalytic and specific binding domains.

    Robert B. Freedman;Peter Klappa;Lloyd W. Ruddock

  • Pre-expression of a sulfhydryl oxidase significantly increases the yields of eukaryotic disulfide bond containing proteins expressed in the cytoplasm of E.coli

    Van Dat Nguyen;Feras Hatahet;Kirsi E H Salo;Eveliina Enlund

  • Guanidine hydrochloride blocks a critical step in the propagation of the prion-like determinant [PSI(+)] of Saccharomyces cerevisiae.

    Simon S. Eaglestone;Lloyd W. Ruddock;Brian S. Cox;Mick F. Tuite

  • EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.

    Silvia Olivari;Tito Cali;Kirsi E.H. Salo;Paolo Paganetti

  • A Major Fraction of Endoplasmic Reticulum-located Glutathione Is Present as Mixed Disulfides with Protein

    Rosemary Bass;Lloyd W. Ruddock;Peter Klappa;Robert B. Freedman

  • A Novel Stress-induced EDEM Variant Regulating Endoplasmic Reticulum-associated Glycoprotein Degradation

    Silvia Olivari;Carmela Galli;Heli Alanen;Lloyd Ruddock

  • Substrate recognition by the protein disulfide isomerases

    Feras Hatahet;Lloyd W. Ruddock

  • Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase.

    Annamari Pirneskoski;Peter Klappa;Mario Lobell;Richard A. Williamson

  • A conserved arginine plays a role in the catalytic cycle of the protein disulphide isomerases.

    Anna Kaisa A.K. Lappi;Marc Lensink;Heli H.I. Alanen;Kirsi E H K.E.H. Salo

  • Insights into Deglutathionylation Reactions DIFFERENT INTERMEDIATES IN THE GLUTAREDOXIN AND PROTEIN DISULFIDE ISOMERASE CATALYZED REACTIONS ARE DEFINED BY THE γ-LINKAGE PRESENT IN GLUTATHIONE

    Mirva J. Peltoniemi;Anna-Riikka Karala;Jaana K. Jurvansuu;Vuokko L. Kinnula

  • Alternative conformations of the x region of human protein disulphide-isomerase modulate exposure of the substrate binding b' domain.

    Van Dat Nguyen;Katrine Wallis;Mark J. Howard;Antti M. Haapalainen

  • Disruption of reducing pathways is not essential for efficient disulfide bond formation in the cytoplasm of E. coli.

    Feras Hatahet;Van Dat Nguyen;Kirsi E H Salo;Lloyd W Ruddock

  • pH-dependence of the dithiol-oxidizing activity of DsbA (a periplasmic protein thiol:disulphide oxidoreductase) and protein disulphide-isomerase: studies with a novel simple peptide substrate

    Lloyd W. Ruddock;Timothy R. Hirst;Robert B. Freedman

Frequent Co-Authors

Robert B. Freedman
Robert B. Freedman University of Warwick
Timothy R. Hirst
Timothy R. Hirst University of Adelaide
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Vuokko L. Kinnula
Vuokko L. Kinnula University of Helsinki
Kari I. Kivirikko
Kari I. Kivirikko University of Oulu
Ylermi Soini
Ylermi Soini University of Eastern Finland
Thomas Kietzmann
Thomas Kietzmann University of Oulu
Claudio Hetz
Claudio Hetz University of Chile
Johanna Myllyharju
Johanna Myllyharju University of Oulu
Mika Rämet
Mika Rämet Oulu University Hospital

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