D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 49 Citations 7,337 102 World Ranking 3376 National Ranking 1536

Research.com Recognitions

Awards & Achievements

2002 - Fellow of the American Academy of Arts and Sciences

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Virus
  • Gene

His scientific interests lie mostly in Microbiology, Enterotoxin, Immunogenicity, Virology and Immunology. His study explores the link between Microbiology and topics such as Toxoid that cross with problems in Immunoglobulin G, Vibrio cholerae and In vitro. His Immunogenicity research is multidisciplinary, relying on both Enterotoxigenic Escherichia coli and Immunity.

His work deals with themes such as Immunization and Recombinant DNA, which intersect with Virology. His Immunology research includes elements of Cytotoxic T cell and Intestinal mucosa. The various areas that John D. Clements examines in his Antigen study include Adjuvant and Antibody.

His most cited work include:

  • Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. (515 citations)
  • Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene. (347 citations)
  • Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques. (224 citations)

What are the main themes of his work throughout his whole career to date?

Microbiology, Immunology, Adjuvant, Immune system and Virology are his primary areas of study. His Microbiology study incorporates themes from Enterotoxigenic Escherichia coli, Heat-labile enterotoxin, Enterotoxin and Immunogenicity. His works in Immunization, Vaccination, Antibody, Immunity and CTL* are all subjects of inquiry into Immunology.

His Adjuvant study combines topics in areas such as T cell, Mutant, Antigen, Bacterial adhesin and Nasal administration. The concepts of his Immune system study are interwoven with issues in Immunogen and Campylobacter. His work carried out in the field of Virology brings together such families of science as Cytotoxic T cell, Feces, Salmonella and Recombinant DNA.

He most often published in these fields:

  • Microbiology (46.02%)
  • Immunology (45.13%)
  • Adjuvant (38.94%)

What were the highlights of his more recent work (between 2010-2021)?

  • Immunology (45.13%)
  • Microbiology (46.02%)
  • Adjuvant (38.94%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Immunology, Microbiology, Adjuvant, Immune system and Antigen. The Immunization, Vaccination, Antibody and Immunity research John D. Clements does as part of his general Immunology study is frequently linked to other disciplines of science, such as Otitis, therefore creating a link between diverse domains of science. His Microbiology research incorporates elements of Enterotoxigenic Escherichia coli, Enterotoxin, Secretion, Toxoid and Vibrio cholerae.

His work deals with themes such as Mucosal vaccine and Vaccine efficacy, which intersect with Adjuvant. Within one scientific family, John D. Clements focuses on topics pertaining to Immunogen under Immune system, and may sometimes address concerns connected to Hepatitis B. His studies deal with areas such as Amino acid, Transfection and Virology as well as Antigen.

Between 2010 and 2021, his most popular works were:

  • Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant (158 citations)
  • Defending the mucosa: adjuvant and carrier formulations for mucosal immunity (96 citations)
  • Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant. (93 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Virus
  • Gene

John D. Clements mainly investigates Adjuvant, Immunology, Antigen, Immune system and Microbiology. He studied Adjuvant and Immunity that intersect with Diarrhea, Toxin and Recombinant DNA. Immunization, Antibody, Immunogen and Mucosal vaccine are the subjects of his Immunology studies.

The study incorporates disciplines such as Enterotoxigenic Escherichia coli, Escherichia coli, Enterotoxin and Virology in addition to Antigen. His study ties his expertise on Immunogenicity together with the subject of Virology. His research in Immune system is mostly concerned with Bacterial vaccine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato.

Carol O. Tacket;Hugh S. Mason;Genevieve Losonsky;John D. Clements.
Nature Medicine (1998)

809 Citations

Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene.

Hugh S. Mason;Tariq A. Haq;John D. Clements;Charles J. Arntzen.
Vaccine (1998)

567 Citations

Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis.

Stephen L. Leib;David Leppert;John Clements;Martin G. Täuber.
Infection and Immunity (2000)

301 Citations

Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques.

Igor M. Belyakov;Zdenek Hel;Brian Kelsall;Vladimir A. Kuznetsov.
Nature Medicine (2001)

284 Citations

Oral Immunogenicity of Human Papillomavirus-Like Particles Expressed in Potato

Heribert Warzecha;Hugh S. Mason;Christopher Lane;Anders Tryggvesson.
Journal of Virology (2003)

214 Citations

Mechanisms for Mucosal Immunogenicity and Adjuvancy of Escherichia coli Labile Enterotoxin

Ichiro Takahashi;Mariarosaria Marinaro;Hiroshi Kiyono;Raymond J. Jackson.
The Journal of Infectious Diseases (1996)

211 Citations

Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant

Elizabeth B. Norton;Louise B. Lawson;Lucy C. Freytag;John D. Clements.
Clinical and Vaccine Immunology (2011)

194 Citations

Evidence for peripheral clearance of cerebral Aβ protein following chronic, active Aβ immunization in PSAPP mice

Cynthia A Lemere;Edward T Spooner;John LaFrancois;Brian Malester.
Neurobiology of Disease (2003)

176 Citations

Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins.

J D Clements.
Infection and Immunity (1990)

164 Citations

Impact of vaccine-induced mucosal high-avidity CD8+CTLs in delay of AIDS viral dissemination from mucosa

Igor M. Belyakov;Vladimir A. Kuznetsov;Brian Kelsall;Dennis Klinman.
Blood (2006)

163 Citations

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