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John D. Clements

John D. Clements

D-Index & Metrics

Immunology

D-Index
71
Citations
13715
World Ranking
2363
National Ranking
1133

Research.com Recognitions

  • 2002 - Fellow of the American Academy of Arts and Sciences
  • 1987 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

John D. Clements is affiliated with Tulane University in the United States and has contributed extensively to the field of medicine, with a focus on several subfields including epidemiology, radiology, nuclear medicine and imaging, infectious diseases, public health, environmental and occupational health, and immunology.

The main topics of their research encompass HIV research and treatment, monoclonal and polyclonal antibodies research, Escherichia coli research studies, multiple myeloma research and treatments, pregnancy and medication impact, child and adolescent health, and breastfeeding practices and influences.

Recent publications by John D. Clements include the following works:

  • Assuring Access to Safe Medicines in Pregnancy and Breastfeeding, 2021, Clinical Pharmacology & Therapeutics
  • Elevated Extracellular cGMP Produced after Exposure to Enterotoxigenic Escherichia coli Heat-Stable Toxin Induces Epithelial IL-33 Release and Alters Intestinal Immunity, 2021, Infection and Immunity
  • Enterotoxigenic Escherichia coli Heat-Stable Toxin Increases the Rate of Zinc Release from Metallothionein and Is a Zinc- and Iron-Binding Peptide, 2020, mSphere
  • A Randomized Trial of Topical Fibrinogen-Depleted Human Platelet Lysate Treatment of Dry Eye Secondary to Chronic Graft-versus-Host Disease, 2022, Ophthalmology Science
  • A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques, 2022, Science Immunology

Frequent collaborators in their work have included:

  • Natalya I. Motyka
  • Elizabeth B. Norton
  • Jacob P. Bitoun
  • Alan Sugar
  • Munira Hussain

John D. Clements has published in various established scientific venues, such as:

  • Clinical Pharmacology & Therapeutics
  • Infection and Immunity
  • Ophthalmology Science
  • Science Immunology
  • mSphere

They have been recognized with notable awards including being named a Fellow of the American Academy of Arts and Sciences in 2002 and a Fellow of the American Association for the Advancement of Science (AAAS) in 1987.

Best Publications

  • Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato.

    Carol O. Tacket;Hugh S. Mason;Genevieve Losonsky;John D. Clements

  • Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene.

    Hugh S. Mason;Tariq A. Haq;John D. Clements;Charles J. Arntzen

  • Mucosal Delivery of Inactivated Influenza Vaccine Induces B-Cell-Dependent Heterosubtypic Cross-Protection against Lethal Influenza A H5N1 Virus Infection

    Terrence M. Tumpey;Mary Renshaw;John D. Clements;Jacqueline M. Katz

  • Matrix metalloproteinases contribute to brain damage in experimental pneumococcal meningitis.

    Stephen L. Leib;David Leppert;John Clements;Martin G. Täuber

  • Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques.

    Igor M. Belyakov;Zdenek Hel;Brian Kelsall;Vladimir A. Kuznetsov

  • Characterization of a Mutant Escherichia coli Heat-Labile Toxin, LT(R192G/L211A), as a Safe and Effective Oral Adjuvant

    Elizabeth B. Norton;Louise B. Lawson;Lucy C. Freytag;John D. Clements

  • Oral Immunogenicity of Human Papillomavirus-Like Particles Expressed in Potato

    Heribert Warzecha;Hugh S. Mason;Christopher Lane;Anders Tryggvesson

  • Mechanisms for Mucosal Immunogenicity and Adjuvancy of Escherichia coli Labile Enterotoxin

    Ichiro Takahashi;Mariarosaria Marinaro;Hiroshi Kiyono;Raymond J. Jackson

  • Recombinant Norwalk Virus-Like Particles Administered Intranasally to Mice Induce Systemic and Mucosal (Fecal and Vaginal) Immune Responses

    Roberto A. Guerrero;Judith M. Ball;Sharon S. Krater;Susan E. Pacheco

  • Evidence for peripheral clearance of cerebral Aβ protein following chronic, active Aβ immunization in PSAPP mice

    Cynthia A Lemere;Edward T Spooner;John LaFrancois;Brian Malester

  • Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant.

    J. Holmgren;L. Bourgeois;N. Carlin;J. Clements

  • Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study.

    Anna Lundgren;Louis Bourgeois;Nils Carlin;John Clements

  • Construction of a nontoxic fusion peptide for immunization against Escherichia coli strains that produce heat-labile and heat-stable enterotoxins.

    J D Clements

  • Impact of vaccine-induced mucosal high-avidity CD8+CTLs in delay of AIDS viral dissemination from mucosa

    Igor M. Belyakov;Vladimir A. Kuznetsov;Brian Kelsall;Dennis Klinman

  • Bacterial Toxins as Mucosal Adjuvants

    L. C. Freytag;J. D. Clements

  • IMMUNOGENIC CONJUGATES OF E. COLI HEAT LABILE SUBUNIT B ENTEROTOXIN

    Anderson Porter W;Clements John D

  • The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT.

    John D. Clements;Elizabeth B. Norton

  • Defending the mucosa: adjuvant and carrier formulations for mucosal immunity

    Louise B Lawson;Elizabeth B Norton;John D Clements

  • CD4 T cells are the only lymphocytes needed to protect mice against rotavirus shedding after intranasal immunization with a chimeric VP6 protein and the adjuvant LT(R192G).

    Monica M. McNeal;John L. VanCott;Anthony H. C. Choi;Matili Basu

  • Antibody-Independent Protection against Rotavirus Infection of Mice Stimulated by Intranasal Immunization with Chimeric VP4 or VP6 Protein

    Anthony H.-C. Choi;Mitali Basu;Monica M. McNeal;John D. Clements

Frequent Co-Authors

Jay A. Berzofsky
Jay A. Berzofsky National Institutes of Health
Genoveffa Franchini
Genoveffa Franchini National Institutes of Health
Brian L. Kelsall
Brian L. Kelsall National Institute of Allergy and Infectious Diseases
Lauren O. Bakaletz
Lauren O. Bakaletz The Ohio State University
Charles J. Arntzen
Charles J. Arntzen Arizona State University
Igor M. Belyakov
Igor M. Belyakov University of Michigan–Ann Arbor
Warren Strober
Warren Strober National Institute of Allergy and Infectious Diseases
Phillip D. Markham
Phillip D. Markham Northrop Grumman (United States)
M. Steven Oberste
M. Steven Oberste Centers for Disease Control and Prevention
Vijay T. John
Vijay T. John Tulane University

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