World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
98
Citations
28242
World Ranking
801
National Ranking
452

Medicine

D-Index
98
Citations
28450
World Ranking
9028
National Ranking
4651

Alfred Ayala publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Alfred Ayala sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 457 publications — 86th percentile

86% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Alfred Ayala D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Alfred Ayala sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 98 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Alfred Ayala is affiliated with Brown University in the United States and has conducted extensive research primarily in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields, including Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Epidemiology, and Infectious Diseases.

The main topics covered in Ayala's research include:

  • Immune Response and Inflammation
  • Sepsis Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Respiratory Support and Mechanisms
  • Neonatal Respiratory Health Research
  • COVID-19 Clinical Research Studies

Recent publications by Ayala include:

  • Blockade of endothelial, but not epithelial, cell expression of PD-L1 following severe shock attenuates the development of indirect acute lung injury in mice (2020), published in American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics (2020), published in Frontiers in Immunology
  • Emerging therapeutic targets for sepsis (2021), published in Expert Opinion on Therapeutic Targets
  • SHP2 inhibitor PHPS1 ameliorates acute kidney injury by Erk1/2-STAT3 signaling in a combined murine hemorrhage followed by septic challenge model (2020), published in Molecular Medicine
  • Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival (2022), published in Frontiers in Immunology

The frequent co-authors collaborating with Ayala are:

  • Chun-Shiang Chung
  • Sean F. Monaghan
  • Alger M. Fredericks
  • William G. Fairbrother
  • Maya Cohen

The main publication venues where Ayala's research appears include:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Shock
  • Journal of Leukocyte Biology
  • Frontiers in Medicine

Ayala's research integrates multiple disciplines to address mechanisms of immune response, inflammation, and treatment approaches particularly focused on sepsis and respiratory conditions. Their publications demonstrate work on immune checkpoints, therapeutic targets, and the modulation of immune cell populations in complex disease models.

Best Publications

  • MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis

    Matthew J Delano;Philip O. Scumpia;Jason S. Weinstein;Dominique Coco

  • Effect of gender and sex hormones on immune responses following shock.

    Martin K. Angele;Martin G. Schwacha;Alfred Ayala;Irshad H. Chaudry;Irshad H. Chaudry

  • PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

    Xin Huang;Fabienne Venet;Yvonne L. Wang;Alain Lepape

  • The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients

    Nicholas S. Ward;Brian Casserly;Alfred Ayala

  • Leukocyte apoptosis and its significance in sepsis and shock.

    Doreen E. Wesche;Joanne L. Lomas-Neira;Mario Perl;Chun-Shiang Chung

  • Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males.

    Rene Zellweger;Matthias W. Wichmann;Matthias W. Wichmann;Alfred Ayala;Alfred Ayala;Susan Stein

  • Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock.

    Edwin A. Deitch;Dazhong Xu;Lisa Franko;Alfred Ayala

  • Early kidney TNF-α expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion

    Kirstan K. Donnahoo;Xianzhong Meng;Alfred Ayala;Mark P. Cain

  • Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients.

    Fabienne Venet;Chun-Shiang Chung;Hakim Kherouf;Anne Geeraert

  • Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage.

    A. Ayala;Ping Wang;Z. F. Ba;M. M. Perrin

  • The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins.

    Wolfgang Ertel;Mary H. Morrison;Ping Wang;Zheng F. Ba

  • Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators

    Alfred Ayala;Crystal D. Herdon;Donna L. Lehman;Carol A. Ayala

  • Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients

    Caroline Guignant;Alain Lepape;Xin Huang;Hakim Kherouf

  • Enhanced immune responses in females, as opposed to decreased responses in males following haemorrhagic shock and resuscitation.

    Matthias W. Wichmann;Matthias W. Wichmann;René Zellweger;Catherine M. DeMaso;Alfred Ayala;Alfred Ayala

  • The new normal: immunomodulatory agents against sepsis immune suppression

    Noelle A. Hutchins;Jacqueline Unsinger;Richard S. Hotchkiss;Alfred Ayala

  • Regulatory T cell populations in sepsis and trauma.

    Fabienne Venet;Chun-Shiang Chung;Guillaume Monneret;Xin Huang

  • Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin.

    Alfred Ayala;Michelle M Perrin;Daniel R Meldrum;Wolfgang Ertel

  • Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release

    Alfred Ayala;Donna L. Lehman;Crystal D. Herdon;Irshad H. Chaudry

  • Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone.

    Matthias W. Wichmann;René Zellweger;Catherine M. DeMaso;Alfred Ayala

  • Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS) : an international expert consensus initiative for improvement of animal modeling in sepsis

    Marcin F. Osuchowski;Alfred Ayala;Soheyl Bahrami;Michael Bauer

  • Testosterone Receptor Blockade After Hemorrhage in Males: Restoration of the Depressed Immune Functions and Improved Survival Following Subsequent Sepsis

    Martin K. Angele;Matthias W. Wichmann;Matthias W. Wichmann;Alfred Ayala;William G. Cioffi

Frequent Co-Authors

Irshad H. Chaudry
Irshad H. Chaudry University of Alabama at Birmingham
Chun-Shiang Chung
Chun-Shiang Chung Brown University
William G. Cioffi
William G. Cioffi Brown University
Ping Wang
Ping Wang Feinstein Institute for Medical Research
Kirby I. Bland
Kirby I. Bland University of Alabama at Birmingham
Fabienne Venet
Fabienne Venet Claude Bernard University Lyon 1
Daniel R. Meldrum
Daniel R. Meldrum University of Florida
Martin G. Schwacha
Martin G. Schwacha The University of Texas Health Science Center at San Antonio
Jonathan S. Reichner
Jonathan S. Reichner Brown University
Lyle L. Moldawer
Lyle L. Moldawer University of Florida

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to various healthcare and research careers. For those interested in clinical practice, pursuing nursing degrees can complement immunology knowledge and lead to patient-centered roles. Many students start by exploring the which lpn programs are easiest to get into, offering a quicker pathway into nursing with practical skills.

For non-nurses aiming to enter the field, there are excellent best online rn programs for non nurses that provide flexible access to registered nursing credentials. These programs enable students to gain critical clinical expertise that complements immunological research or patient care.

Accelerated options like easiest absn programs to get into allow fast-tracking through a Bachelor of Science in Nursing, ideal for those with prior degrees looking to pivot toward healthcare roles swiftly.

Moreover, for advanced clinical practice, exploring the accelerated np program options can help immunology graduates specialize as nurse practitioners. These careers involve diagnosing and treating diseases, highlighting the intersection between immunology studies and direct patient impact.

Best Scientists Citing Alfred Ayala

Trending Scientists

Recently Published Articles