World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
115
Citations
50471
World Ranking
395
National Ranking
244

Medicine

D-Index
115
Citations
51050
World Ranking
4522
National Ranking
2459

Overview

Lyle L. Moldawer is affiliated with the University of Florida in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with notable contributions in several related subfields including Epidemiology, Immunology, Critical Care and Intensive Care Medicine, Pulmonary and Respiratory Medicine, and Infectious Diseases.

The scientist's work extensively covers topics such as Sepsis Diagnosis and Treatment, Immune Response and Inflammation, Intensive Care Unit Cognitive Disorders, Inflammation biomarkers and pathways, Immune cells in cancer, COVID-19 Clinical Research Studies, and Adrenal Hormones and Disorders.

Recent significant publications include:

  • Redefining critical illness, 2022, Nature Medicine
  • Immunotherapies for COVID-19: lessons learned from sepsis, 2020, The Lancet Respiratory Medicine
  • Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness, 2021, Journal of Clinical Medicine
  • Dysregulated Immunity and Immunotherapy after Sepsis, 2021, Journal of Clinical Medicine
  • The impact of sarcopenia and acute muscle mass loss on long-term outcomes in critically ill patients with intra-abdominal sepsis, 2021, Journal of Cachexia Sarcopenia and Muscle

The network of frequent co-authors comprises Philip A. Efron, Scott C. Brakenridge, Alicia M. Mohr, Dijoia B. Darden, and Frederick A. Moore.

Moldawer's publications are often found in venues such as Shock, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, Critical Care Explorations, and Critical Care.

Best Publications

  • Genomic responses in mouse models poorly mimic human inflammatory diseases

    Seok Junhee Seok;Shaw Warren H. Shaw Warren;G. Cuenca Alex;N. Mindrinos Michael

  • A network-based analysis of systemic inflammation in humans

    Steve E. Calvano;Wenzhong Xiao;Daniel R. Richards;Ramon M. Felciano

  • Sepsis and septic shock

    Richard R.S. Hotchkiss;Lyle Linc Moldawer;Steven Opal;Konrad Reinhart

  • A genomic storm in critically injured humans

    Wenzhong Xiao;Wenzhong Xiao;Michael N. Mindrinos;Junhee Seok;Joseph Cuschieri

  • Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

    K J Van Zee;T Kohno;E Fischer;C S Rock

  • Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.

    Y Fong;K J Tracey;L L Moldawer;D G Hesse

  • Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care.

    Lori F. Gentile;Alex G. Cuenca;Philip A. Efron;Darwin Ang

  • Anti-TNF-alpha therapies: the next generation

    Michael A. Palladino;Frances Rena Bahjat;Emmanuel A. Theodorakis;Lyle L. Moldawer

  • MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis

    Matthew J Delano;Philip O. Scumpia;Jason S. Weinstein;Dominique Coco

  • Sepsis syndromes: understanding the role of innate and acquired immunity.

    Andreas Oberholzer;Caroline Oberholzer;Lyle L. Moldawer

  • Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.

    S D Wolpe;G Davatelis;B Sherry;B Beutler

  • Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome.

    Juan C Mira;Lori F Gentile;Brittany J Mathias;Philip A Efron

  • Structural basis for the proinflammatory cytokine activity of high mobility group box 1.

    Jianhua Li;Riikka Kokkola;Siamak Tabibzadeh;Runkuan Yang

  • Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins

    Y. Fong;L. L. Moldawer;M. Marano;H. Wei

  • ORGAN APOPTOSIS IS DEPENDENT ON GLUCOCORTICOIDS BUT NOT FasL EARLY AFTER BURN INJURY

    K. Fukuzuka;R. Minter;J. Rectenwald;C. K. Edwards

  • The biologic characteristics of cytokines and their implication in surgical injury.

    Y Fong;L L Moldawer;G T Shires;S F Lowry

  • The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans.

    Y M Fong;M A Marano;L L Moldawer;H Wei

  • A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia.

    Harold S. Ginsberg;Lyle L. Moldawer;Pravinkumar B. Sehgal;Miriam Redington

  • Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice.

    M Labow;D Shuster;M Zetterstrom;P Nunes

  • Cost and Mortality Associated With Postoperative Acute Kidney Injury

    Charles Hobson;Tezcan Ozrazgat-Baslanti;Adrienne Kuxhausen;Paul Thottakkara

  • IL-8 in septic shock, endotoxemia, and after IL-1 administration.

    K J Van Zee;L E DeForge;E Fischer;M A Marano

Frequent Co-Authors

Henry V. Baker
Henry V. Baker University of Florida
Frederick A. Moore
Frederick A. Moore University of Florida
Stephen F. Lowry
Stephen F. Lowry Rutgers, The State University of New Jersey
Edward M. Copeland
Edward M. Copeland University of Florida
Ronald G. Tompkins
Ronald G. Tompkins Harvard University
Christiaan Leeuwenburgh
Christiaan Leeuwenburgh University of Florida
Wenzhong Xiao
Wenzhong Xiao Harvard University
Ronald V. Maier
Ronald V. Maier University of Washington
Michael J. Clare-Salzler
Michael J. Clare-Salzler University of Florida
Michael N. Mindrinos
Michael N. Mindrinos Stanford University

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