Hector R. Wong

Overview

Best Publications

• Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children

  Scott L. Weiss;Mark J. Peters;Waleed Alhazzani;Michael S.D. Agus

  2018
  Citations

• Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

  Brendon P Scicluna;Lonneke A van Vught;Aeilko H Zwinderman;Maryse A Wiewel

  592
  Citations

• Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide

  Basilia Zingarelli;Michael O'Connor;Hector Wong;Andrew L. Salzman

  465
  Citations

• Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock.

  Derek S. Wheeler;Prasad Devarajan;Qing Ma;Kelli Harmon

  431
  Citations

• Time for a neonatal–specific consensus definition for sepsis

  James L. Wynn;Hector R. Wong;Hector R. Wong;Thomas P. Shanley;Matthew J. Bizzarro

  366
  Citations

• Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFκB activation

  Eli Gilad;Hector R. Wong;Basilia Zingarelli;László Virág

  349
  Citations

• Unsupervised analysis of transcriptomics in bacterial sepsis across multiple datasets reveals three robust clusters

  Timothy E. Sweeney;Tej D. Azad;Michele Donato;Winston A. Haynes

  334
  Citations

• Pathophysiology and Treatment of Septic Shock in Neonates

  James L. Wynn;Hector R. Wong

  318
  Citations

• A comprehensive time-course-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set

  Timothy E. Sweeney;Aaditya Shidham;Hector R. Wong;Purvesh Khatri

  312
  Citations

• Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

  Timothy E. Sweeney;Hector R. Wong;Hector R. Wong;Purvesh Khatri

  307
  Citations

• Nuclear factor-κB as a therapeutic target in critical care medicine

  Basilia Zingarelli;Maeve Sheehan;Hector R. Wong

  290
  Citations

• Developing a clinically feasible personalized medicine approach to pediatric septic shock.

  Hector R. Wong;Natalie Z. Cvijanovich;Nick Anas;Geoffrey L. Allen

  286
  Citations

• Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

  Hector R. Wong;Thomas P. Shanley;Bhuvaneswari Sakthivel;Natalie Cvijanovich

  273
  Citations

• Identification of pediatric septic shock subclasses based on genome-wide expression profiling.

  Hector R. Wong;Natalie Z Cvijanovich;Richard Lin;Geoffrey L. Allen

  267
  Citations

• Prognostic and predictive enrichment in sepsis.

  Natalja L Stanski;Hector R Wong;Hector R Wong

  261
  Citations

• The host response to sepsis and developmental impact

  James Wynn;Timothy T. Cornell;Hector R. Wong;Thomas P. Shanley

  252
  Citations

• Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children

  Rajit K. Basu;Michael Zappitelli;Lori Brunner;Yu Wang

  246
  Citations

• Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats.

  Rajesh Aneja;Paul W. Hake;Timothy J. Burroughs;Alvin G. Denenberg

  241
  Citations

• Salmonella Flagellin-Dependent Proinflammatory Responses Are Localized to the Conserved Amino and Carboxyl Regions of the Protein

  Tonyia D. Eaves-Pyles;Hector R. Wong;Kelli Odoms;Richard B. Pyles;Richard B. Pyles

  239
  Citations

• Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum*

  Hector R. Wong;Natalie Cvijanovich;Geoffrey L. Allen;Richard Lin

  234
  Citations