Her main research concerns Nitric oxide, Peroxynitrite, Inflammation, Pharmacology and Biochemistry. Her Nitric oxide research is multidisciplinary, incorporating perspectives in Molecular biology, Lipopolysaccharide and Interleukin 10. Peroxynitrite is a subfield of Superoxide that Basilia Zingarelli explores.
Her Inflammation course of study focuses on Melatonin and Antioxidant and Prostacyclin. The study incorporates disciplines such as Ex vivo, Reperfusion injury, Ischemia, Endothelium and IκB kinase in addition to Pharmacology. Her studies deal with areas such as IκBα and Mononuclear cell infiltration as well as Nitrotyrosine.
Pharmacology, Nitric oxide, Internal medicine, Endocrinology and Peroxynitrite are her primary areas of study. In her research on the topic of Pharmacology, Intensive care is strongly related with Immunology. The Nitric oxide study combines topics in areas such as Inflammation, Molecular biology and Biochemistry.
Basilia Zingarelli has researched Internal medicine in several fields, including Resuscitation and Cardiology. Her research integrates issues of Interleukin 6 and Peroxisome proliferator-activated receptor, Receptor in her study of Endocrinology. She interconnects Zymosan and Pathogenesis in the investigation of issues within Peroxynitrite.
Basilia Zingarelli focuses on Sepsis, Internal medicine, Immunology, Endocrinology and Inflammation. Her research in Sepsis intersects with topics in Cancer research, Clinical trial and Intensive care medicine. Her work carried out in the field of Immunology brings together such families of science as Peritoneal fluid and Pharmacology.
Her Pharmacology study deals with Superior mesenteric artery intersecting with Barrier function. Her Endocrinology research includes themes of AMP-activated protein kinase, Interleukin 6 and Peroxisome proliferator-activated receptor. Basilia Zingarelli combines subjects such as Lung and Host response with her study of Inflammation.
Basilia Zingarelli mainly investigates Sepsis, Immunology, Inflammation, Intensive care medicine and Clinical trial. Basilia Zingarelli mostly deals with Septic shock in her studies of Sepsis. She has included themes like Peritoneal fluid and Pharmacology in her Immunology study.
She incorporates Pharmacology and Imipenem in her studies. Her studies in Inflammation integrate themes in fields like Cancer research and Matrix metalloproteinase. Her Intensive care medicine research integrates issues from Guideline, MEDLINE and Organ dysfunction.
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DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite
Csaba Szabo;Basilia Zingarelli;Michael O'Connor;Andrew L. Salzman.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide
Basilia Zingarelli;Michael O'Connor;Hector Wong;Andrew L. Salzman.
Journal of Immunology (1996)
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
Csaba Szabo;Salvatore Cuzzocrea;Basilia Zingarelli;Michael O'Connor.
Journal of Clinical Investigation (1997)
Genetic Disruption of Poly (ADP-Ribose) Synthetase Inhibits the Expression of P-Selectin and Intercellular Adhesion Molecule-1 in Myocardial Ischemia/Reperfusion Injury
Basilia Zingarelli;Andrew L. Salzman;Csaba Szabó.
Circulation Research (1998)
MELATONIN IS A SCAVENGER OF PEROXYNITRITE
Eli Gilad;Salvatore Cuzzocrea;Basilia Zingarelli;Andrew L. Salzman.
Life Sciences (1997)
Crucial Role of Endogenous Interleukin-10 Production in Myocardial Ischemia/Reperfusion Injury
Zequan Yang;Basilia Zingarelli;Csaba Szabó.
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.
Csaba Szabó;László Virág;Salvatore Cuzzocrea;Gwen S. Scott.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Salvatore Cuzzocrea;Basilia Zingarelli;Eli Gilad;Paul Hake.
Journal of Pineal Research (1997)
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFκB activation
Eli Gilad;Hector R. Wong;Basilia Zingarelli;László Virág.
The FASEB Journal (1998)
Nuclear factor-κB as a therapeutic target in critical care medicine
Basilia Zingarelli;Maeve Sheehan;Hector R. Wong.
Critical Care Medicine (2003)
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