Per-Olof Hasselgren

Overview

Best Publications

• IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

  Dongsheng Cai;J. Daniel Frantz;J. Daniel Frantz;Nicholas E. Tawa;Nicholas E. Tawa;Peter A. Melendez;Peter A. Melendez

  1591
  Citations

• Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group.

  Fisher Cj;Dhainaut Jf;Opal Sm;Pribble Jp

  1513
  Citations

• Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat

  Aaron M Cypess;Andrew P White;Cecile Vernochet;Tim J Schulz

  740
  Citations

• Glucocorticoids and muscle catabolism.

  Per-Olof Hasselgren

  400
  Citations

• Muscle cachexia: current concepts of intracellular mechanisms and molecular regulation.

  Per-Olof Hasselgren;Josef E. Fischer

  387
  Citations

• Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle.

  Greg Tiao;Scott Hobler;Jing Jing Wang;Tory A. Meyer

  363
  Citations

• Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle.

  Greg Tiao;J. M. Fagan;N. Samuels;J. H. James

  356
  Citations

• Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

  G. Tiao;J. Fagan;V. Roegner;M. Lieberman

  348
  Citations

• Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle

  Curtis J Wray;Joshua M V Mammen;Joshua M V Mammen;Dan D. Hershko;Dan D. Hershko;Per Olof Hasselgren

  302
  Citations

• The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer

  Arthur Williams;Xiaoyan Sun;Josef E. Fischer;Per-Olof Hasselgren

  259
  Citations

• Sepsis stimulates release of myofilaments in skeletal muscle by a calcium-dependent mechanism

  Arthur B. Williams;Gabrielle M. Decourten-Myers;Josef E. Fischer;Guangju Luo

  253
  Citations

• DEXAMETHASONE AND CORTICOSTERONE INDUCE SIMILAR, BUT NOT IDENTICAL, MUSCLE WASTING RESPONSES IN CULTURED L6 AND C2C12 MYOTUBES

  Michael Menconi;Patricia Gonnella;Victoria Petkova;Stewart Lecker

  222
  Citations

• Total and myofibrillar protein breakdown in different types of rat skeletal muscle: effects of sepsis and regulation by insulin.

  P.-O. Hasselgren;J. H. James;J. H. James;D. W. Benson;D. W. Benson;M. Hall-Angeras;M. Hall-Angeras

  211
  Citations

• Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle. Implications for increased muscle lactate production in sepsis.

  J H James;C H Fang;S J Schrantz;P O Hasselgren

  200
  Citations

• Evidence that tumor necrosis factor participates in the regulation of muscle proteolysis during sepsis.

  Oded Zamir;Per Olof Hasselgren;Steven L. Kunkel;Janice Frederick

  198
  Citations

• Molecular regulation of muscle cachexia: it may be more than the proteasome.

  Per Olof Hasselgren;Per Olof Hasselgren;Curtis Wray;Joshua Mammen

  197
  Citations

• Beneficial effect of allopurinol in liver ischemia.

  G Nordström;T Seeman;P O Hasselgren

  196
  Citations

• Intestinal permeability is reduced and IL-10 levels are increased in septic IL-6 knockout mice

  Quan Wang;Cheng Hui Fang;Per-Olof Hasselgren;Per-Olof Hasselgren

  183
  Citations

• Treatment of rats with calpain inhibitors prevents sepsis-induced muscle proteolysis independent of atrogin-1/MAFbx and MuRF1 expression

  Moin U. Fareed;Amy R. Evenson;Wei Wei;Michael Menconi

  175
  Citations

• Preoperative evaluation of thyroid nodules with 18FDG-PET/CT

  Jamie C. Mitchell;Frederick Grant;Amy R. Evenson;J.A. Parker

  172
  Citations