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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
15748
World Ranking
11802
National Ranking
305

Overview

Eric Kalkhoven is affiliated with Utrecht University in the Netherlands and has a research portfolio focused on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology. Their work spans several subfields, including molecular biology, immunology, physiology, cell biology, and surgery.

The scientific topics addressed in their research include adipose tissue and metabolism, epigenetics and DNA methylation, immune cell function and interaction, bladder and urothelial cancer treatments, peroxisome proliferator-activated receptors, endoplasmic reticulum stress and disease, and immune cells in cancer.

Recent papers authored or co-authored by Eric Kalkhoven include:

  • PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action, 2021, Frontiers in Endocrinology
  • FXR Isoforms Control Different Metabolic Functions in Liver Cells via Binding to Specific DNA Motifs, 2020, Gastroenterology
  • Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment, 2020, Frontiers in Endocrinology
  • Splice variants of metabolic nuclear receptors: Relevance for metabolic disease and therapeutic targeting, 2021, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  • PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation, 2022, Nature Communications

Frequent co-authors working with Eric Kalkhoven include Anouska Borgman, Miguel Hernández-Quiles, Imogen Morris, Robert van Es, and Harmjan R. Vos.

Eric Kalkhoven's research is commonly published in journals such as Frontiers in Endocrinology, Nature Metabolism, Gastroenterology, Nature Communications, and the International Journal of Molecular Sciences. Their contributions have appeared multiple times in Frontiers in Endocrinology and Nature Metabolism.

Best Publications

  • A signature motif in transcriptional co-activators mediates binding to nuclear receptors.

    David M. Heery;Eric Kalkhoven;Susan Hoare;Malcolm G. Parker

  • Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

    Grigorios Krey;Olivier Braissant;Fabienne L’Horset;Eric Kalkhoven

  • Negative interaction between the RelA(p65) subunit of NF-kappaB and the progesterone receptor.

    Eric Kalkhoven;Sacha Wissink;Paul T. van der Saag;Bart van der Burg

  • Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

    Jorg Van Loosdregt;Yvonne Vercoulen;Teun Guichelaar;Yoony Y J Gent

  • Adipose tissue-resident immune cells: key players in immunometabolism.

    Henk S. Schipper;Berent J. Prakken;Eric Kalkhoven;Marianne Boes

  • Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor

    Eric Kalkhoven;Janet E. Valentine;David M. Heery;Malcolm G. Parker

  • Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids

    Jeanine M.L. Roodhart;Laura G.M. Daenen;Edwin C.A. Stigter;Henk Jan Prins

  • Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity

    Jorg van Loosdregt;Veerle Fleskens;Juan Fu;Arjan B. Brenkman

  • AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors.

    P. M. A. Henttu;E. Kalkhoven;M. G. Parker

  • Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γ.

    Henner F. Farin;Wouter R. Karthaus;Pekka Kujala;Maryam Rakhshandehroo

  • Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.

    Sheril Alex;Katja Lange;Tom Amolo;Jeffrey S Grinstead;Jeffrey S Grinstead

  • Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery

    Katrin Strassburg;Annemarie M. L. Huijbrechts;Kirsten A. Kortekaas;Jan H. Lindeman

  • PPARgamma in Metabolism, Immunity, and Cancer: Unified and Diverse Mechanisms of Action.

    Miguel Hernandez-Quiles;Marjoleine F Broekema;Marjoleine F Broekema;Eric Kalkhoven

  • Natural killer T cells in adipose tissue prevent insulin resistance

    Henk S Schipper;Maryam Rakhshandehroo;Stan F J van de Graaf;Koen Venken

  • Prospective functional classification of all possible missense variants in PPARG

    Amit R. Majithia;Ben Tsuda;Maura Agostini;Keerthana Gnanapradeepan

  • Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines

    E. Kalkhoven;B. A. J. Roelen;J. P. De Winter;C. L. Mummery

  • Posttranslational Modifications of PPAR‐γ: Fine‐tuning the Metabolic Master Regulator

    Olivier van Beekum;Veerle Fleskens;Eric Kalkhoven

  • Identification of human exercise-induced myokines using secretome analysis

    Milène Catoire;Marco Mensink;Eric Kalkhoven;Patrick Schrauwen

  • Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) but not PPARα serves as a plasma free fatty acid sensor in liver.

    Linda M. Sanderson;Tatjana Degenhardt;Arjen Koppen;Eric Kalkhoven

  • Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein–Taybi syndrome

    Eric Kalkhoven;Jeroen H. Roelfsema;Hans Teunissen;Annemieke den Boer

Frequent Co-Authors

Sander Kersten
Sander Kersten Wageningen University & Research
Berent J. Prakken
Berent J. Prakken Utrecht University
Frank L.J. Visseren
Frank L.J. Visseren Utrecht University
Marianne Boes
Marianne Boes Utrecht University
Susanne Mandrup
Susanne Mandrup University of Southern Denmark
Patrick Schrauwen
Patrick Schrauwen Maastricht University
Wilco de Jager
Wilco de Jager University Medical Center Utrecht
Paul J. Coffer
Paul J. Coffer Utrecht University
Malcolm G. Parker
Malcolm G. Parker Imperial College London
Michael Müller
Michael Müller University of East Anglia

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