World's Best Scientists 2026 revealed!
Frank Claessens

Frank Claessens

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
46250
World Ranking
3788
National Ranking
62

Overview

Frank Claessens is affiliated with KU Leuven in Belgium and has an extensive research portfolio primarily focused on medicine and biochemistry, genetics, and molecular biology. Their work addresses a range of topics within the broader fields of pulmonary and respiratory medicine, endocrinology, diabetes and metabolism, genetics, and cancer research.

Their recent publications reflect an emphasis on prostate cancer, hormonal studies, and genetic analysis. Notable papers include:

  • "An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk," 2020, Nature Communications
  • "Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse," 2021, Nature Communications
  • "Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer," 2021, Nature Reviews Urology
  • "Role of sex hormone-binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology," 2022, Cellular and Molecular Life Sciences
  • "Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan," 2020, Nature Communications

Claessens has collaborated frequently with several researchers, including:

  • Wout Devlies
  • Steven Joniau
  • Dirk Vanderschueren
  • Gaëtan Devos
  • Karel David

Publications by Claessens have appeared in several venues with multiple contributions to:

  • European Urology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Endocrine Abstracts
  • Nature Communications
  • Endocrinology

The main fields of study where Claessens has made contributions are:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these domains, Claessens's work spans several subfields:

  • Pulmonary and Respiratory Medicine
  • Molecular Biology
  • Endocrinology, Diabetes and Metabolism
  • Genetics
  • Cancer Research

The primary research topics covered include:

  • Prostate Cancer Treatment and Research
  • Hormonal and reproductive studies
  • Prostate Cancer Diagnosis and Treatment
  • Sexual Differentiation and Disorders
  • Cancer, Lipids, and Metabolism
  • Estrogen and related hormone effects
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Best Publications

  • Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

    Leandra Abarca-Gómez;Ziad A Abdeen;Zargar Abdul Hamid;Niveen M Abu-Rmeileh

  • Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants

    Mariachiara Di Cesare;Mariachiara Di Cesare;James Bentham;Gretchen A Stevens;Bin Zhou

  • Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants

    Bin Zhou;Yuan Lu;Kaveh Hajifathalian;James Bentham

  • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

    Bin Zhou;Rodrigo M Carrillo-Larco;Goodarz Danaei;Leanne M Riley

  • Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

    Bin Zhou;James Bentham;Mariachiara Di Cesare;Honor Bixby

  • A century of trends in adult human height

    James Bentham;Mariachiara Di Cesare;Mariachiara Di Cesare;Gretchen A. Stevens;Bin Zhou

  • A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.

    Karel De Gendt;Johannes V. Swinnen;Philippa T. K. Saunders;Luc Schoonjans

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Honor Bixby;James Bentham;Bin Zhou;Mariachiara Di Cesare

  • Estrogens and Androgens in Skeletal Physiology and Pathophysiology.

    Maria Almeida;Michaël R. Laurent;Vanessa Dubois;Frank Claessens

  • Fracture Risk and Zoledronic Acid Therapy in Men with Osteoporosis

    Steven Boonen;Jean-Yves Reginster;Jean-Marc Kaufman;Kurt Lippuner

  • The AF1 and AF2 Domains of the Androgen Receptor Interact with Distinct Regions of SRC1

    Charlotte L. Bevan;Sue Hoare;Frank Claessens;David M. Heery

  • Structural basis of androgen receptor binding to selective androgen response elements

    Paul L. Shaffer;Arif Jivan;D. Eric Dollins;Frank Claessens

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

    Andrea Rodriguez-Martinez;Bin Zhou;Marisa K. Sophiea;James Bentham

  • Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men

    Sabine Verschueren;Evelien Gielen;T W O'Neill;S R Pye

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • The Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription

    Philippe Alen;Frank Claessens;Guido Verhoeven;Wilfried Rombauts

  • Sex Steroid Actions in Male Bone

    Dirk Vanderschueren;Michaël R. Laurent;Frank Claessens;Evelien Gielen

  • Diverse roles of androgen receptor (AR) domains in AR-mediated signaling:

    Frank Claessens;Sarah Denayer;Nora Van Tilborgh;Stefanie Kerkhofs

  • An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.

    Lang Wu;Yaohua Yang;Xingyi Guo;Xiao Ou Shu

Frequent Co-Authors

Steven Joniau
Steven Joniau KU Leuven
Steven Boonen
Steven Boonen KU Leuven
Børge G. Nordestgaard
Børge G. Nordestgaard University of Copenhagen
Frederick C. W. Wu
Frederick C. W. Wu University of Manchester
Hermann Brenner
Hermann Brenner German Cancer Research Center
David E. Neal
David E. Neal University of Cambridge
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Johanna Schleutker
Johanna Schleutker Turku University Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Frank Claessens

Trending Scientists